- Original Article
- Allergy
- Nasal eosinophilia and eosinophil peroxidase in children and adolescents with rhinitis
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Yeonu Choi, Haeun Jeon, Eun Ae Yang, Jong-Seo Yoon, Hyun Hee Kim
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Clin Exp Pediatr. 2019;62(9):353-359. Published online April 24, 2019
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Background: Researchers have shown that eosinophil peroxidase (EPO) is a relatively accurate marker of eosinophilia and eosinophil activity. However, its use as a marker of eosinophilic inflammation in nasal secretions is limited because the diagnostic cutoff values of EPO for use as a one-time test for allergic diseases such as allergic rhinitis have not been established.
Purpose: To identify the correlation... |
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- The effect of rhinovirus on airway inflammation in a murine asthma model
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Eugene Kim, Huisu Lee, Hyun Sook Kim, Sulmui Won, Eu Kyoung Lee, Hwan Soo Kim, Kyongwon Bang, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Jin Tack Kim, Joon Sung Lee
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Clin Exp Pediatr. 2013;56(11):482-489. Published online November 27, 2013
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Purpose The aim of the present study was to investigate the differences in lower airway inflammatory immune responses, including cellular responses and responses in terms of inflammatory mediators in bronchoalveolar lavage fluid (BALF) and the airway, to rhinovirus (RV) infection on asthma exacerbation by comparing a control and a murine asthma model, with or without RV infection. MethodsBALB/c mice were intraperitoneally injected... |
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- Effect of respiratory syncytial virus infection on regulated on activation, normal T-cells expressed and secreted production in a murine model of asthma
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Yanghua Ju, Seung Jun Choi, Huisu Lee, Hyun Sook Kim, Sulmui Won, Yoon Hong Chun, Jong-Seo Yoon, Hyun Hee Kim, Joon Sung Lee
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Clin Exp Pediatr. 2011;54(11):456-462. Published online November 30, 2011
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Purpose Synthesis of regulated on activation, normal T-cells expressed and secreted (RANTES) in the airway has previously been shown to be elevated after respiratory syncytial virus (RSV) infection. However, since few studies have examined whether RSV-infected asthma patients express a higher level of RANTES than do normal individuals, we used a murine model of asthma to address this question. MethodsWe prepared Dermatophagoides... |
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