- Original Article
- 1828G>A polymorphism of the UDP-glucuronosyltransferase gene (UGT1A1) for neonatal hyperbilirubinemia in Koreans
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Ja Young Kim, Mi Yeoun Kim, Ji Sook Kim, Eun Ryoung Kim, Seo Hyun Yoon, Hee Jae Lee, Joo Ho Chung
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Clin Exp Pediatr. 2006;49(1):34-39. Published online January 15, 2006
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Purpose : The incidence of neonatal hyperbilirubinemia is twice as high in East Asians as in Caucasians. However, its metabolic basis has not been clearly explained. The UDP-glucuronosyltransferase gene(UGT1A1) mutation was found to be a risk factor of neonatal hyperbilirubinemia. We studied whether neonatal hyperbilirubinemia is associated with the 1828G>A(rs 10929303) polymorphism of the UGT1A1 gene, which encodes for a... |
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- Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma.
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Ja Young Kim, Moon Whan Lee, Ju Hyung Kim, Pyoung Han Hwang, Jung Soo Kim
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Clin Exp Pediatr. 1990;33(12):1735-1740. Published online December 31, 1990
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The improvement in survival for childhood cancer has been achieved through the use of multiple-
agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of
survival has been the development of second malignant neoplasm.
We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic
sarcoma after successful treatment of retinoblastoma. At 3 years of his age,... |
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- Changes of PPD-Specific Immunoglobulin in Pulmonary Tuberculosis After Treatment.
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Ja Young Kim, Mun Hwan Lee, Pyoung Han Hwang, Chan Uhng Joo, Jung Soo Kim
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Clin Exp Pediatr. 1990;33(12):1647-1655. Published online December 31, 1990
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The definite diagnosis and precise assessment of response to therapy is still a problem in childhood
tuberculosis because these patients rarely produce sputum and if obtained it may be negative. For this
reason, diagnosis rely largely on the clinical and X-ray examination, which have a low specificity and
high proportion of false positive results.
Recently immunologic diagnosis of tuberculosis using enzyme-linked immunosorbent assay (ELISA)
was... |
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