Journal of the Korean Pediatric Society 1990;33(12):1735-1740.
Published online December 31, 1990.
Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma.
Ja Young Kim, Moon Whan Lee, Ju Hyung Kim, Pyoung Han Hwang, Jung Soo Kim
Department of Pediatrics, College of Medicine, Chonbuk National University, Chonju, Korea
망막아세포종 치료후 이차성 종양으로 발생한 골육종 1례
김자영, 이문환, 김주형, 황평한, 김정수
전북대학교 의과대학 소아과학교실
Received: 5 July 1990   • Accepted: 28 September 1990
The improvement in survival for childhood cancer has been achieved through the use of multiple- agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of survival has been the development of second malignant neoplasm. We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic sarcoma after successful treatment of retinoblastoma. At 3 years of his age, he was diagnosed as retinoblastoma and managed by enucleation of left eye at a university hospital in Seoul. Ten years later, painful swelling was noted on the right ankle joint. Histopathological findings revealed osteblastic osteogenic sarcoma and metastasis to lung was detected on chest X-ray. He received multiple-agent chemotherapy for one time. Thereafter, he was lost to follow-up and expired 9 months after diagnosis of second mailgnant neoplasm.
Key Words: Second malignant neoplasm, Osteogenic sarcoma, Retinoblastoma

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