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Case Report
A pediatric case of Brugada syndrome diagnosed by fever-provoked ventricular tachycardia
Geena Kim, Ye-Chan Kyung, I-Seok Kang, Jinyoung Song, June Huh, Young Keun On
Clin Exp Pediatr. 2014;57(8):374-378.   Published online August 25, 2014

Brugada syndrome is a rare channelopathy associated with the SCN5A gene that causes fatal ventricular arrhythmias. This case of Brugada syndrome, in which ventricular tachycardia (VT) was provoked by high fever, is the first report in a Korean child. The boy had retinoblastoma of his left eye diagnosed at 16 months of age. After chemotherapy, he contracted a catheter-related infection...

Original Article
Combined chemotherapy and intra-arterial chemotherapy of retinoblastoma
Saerom Choi, Jung Woo Han, Hyosun Kim, Beom Sik Kim, Dong Joon Kim, Sung Chul Lee, Chuhl Joo Lyu
Clin Exp Pediatr. 2013;56(6):254-259.   Published online June 21, 2013
Purpose

Retinoblastoma (RB) is the most common primary malignant intraocular tumor in children. Although systemic chemotherapy has been the primary treatment, intra-arterial chemotherapy (IAC) represents a new treatment option. Here, we performed alternate systemic chemotherapy and IAC and retrospectively reviewed the efficacy and safety of this approach.

Methods

Patients diagnosed with intraocular RB between January 2000 and December 2011 at Severance Children's Hospital,...

Bilateral retinoblastoma: Long-term follow-up results from a single institution
Sang Yul Choi, Dong Hwan Kim, Kang Min Lee, Hyun Jae Lee, Mi-Sook Kim, Tai-Won Lee, Sang Wook Choi, Dong Ho Kim, Kyung Duk Park, Jun Ah Lee
Clin Exp Pediatr. 2009;52(6):674-679.   Published online June 15, 2009
Purpose : The authors aimed to analyze the long-term effects of treatments, especially external beam radiotherapy (EBRT), in bilateral retinoblastoma patients. Methods : This retrospective study analyzed the medical records of 22 bilateral retinoblastoma patients who were registered between October, 1987 and October, 1998 and followed-up for more than 10 years. They were treated by enucleation, EBRT, and systemic chemotherapy....
Effects of enucleation and chemotherapy in advanced intraocular and intraorbital retinoblastoma with or without radiotherapy
Jae Min Lee, Hyun Dong Lee, Jeong Ok Hah
Clin Exp Pediatr. 2008;51(1):84-88.   Published online January 15, 2008
Purpose : Radiotherapy is effective in local treatment for retinoblastoma. However, asymmetric facial hypoplasia after radiation is a serious late effect. This study was performed to investigate the effects of enucleation and chemotherapy with or without radiotherapy in advanced intraocular and intraorbital retinoblastoma. Methods : Between 1985 October and 2006 December, the records of thirty five patients who were diagnosed as...
Outcome after Treatment of Retinoblastoma
Hyoung Soo Choi, Ki Woong Seong, Jae Kyung Lee, Kyung Ha Yoo, Hee Young Shin, Young Suk Yu, Hyo Seop Ahn
Clin Exp Pediatr. 1997;40(4):519-530.   Published online April 15, 1997
Purpose : Current treatment in retinoblastoma aims to save life and preserve useful vision by using combined modality therapy. This study was performed to determine the outcome after treatment of retinoblastoma. Methods : Medical records of all cases of retinoblastoma seen at Seoul National University Children's Hospital from September 1986 to April 1995 were reviewed. During this period, the treatment method...
Osteogenic Sarcoma as Second Malignant Neoplasm After Treatment of Retinoblastoma.
Ja Young Kim, Moon Whan Lee, Ju Hyung Kim, Pyoung Han Hwang, Jung Soo Kim
Clin Exp Pediatr. 1990;33(12):1735-1740.   Published online December 31, 1990
The improvement in survival for childhood cancer has been achieved through the use of multiple- agent chemotherapy and radiotherapy. However, one of the limitations to quality and length of survival has been the development of second malignant neoplasm. We exprienced a case of second malignant neoplasm in 13-year-old boy who developed osteogenic sarcoma after successful treatment of retinoblastoma. At 3 years of his age,...
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