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Original Article
Prognosis of Bacterial Meningitis based on Cerebrospinal Fluid Culture
Yun Ju Lee, Won Sung Lee, Kyoung Sim Kim, Ki Bok Kim
Clin Exp Pediatr. 1998;41(5):614-621.   Published online May 15, 1998
Purpose : The present study was undertaken to assess whether the results of cerebrospinal fluid (CSF) culture are related to prognosis. Methods : Subjected to this study were 51 cases admitted to our department who had been diagnosed as bacterial meningitis. They were divided into two groups, Group Ⅰ(20) with positive CSF culture and Group Ⅱ(31) with negative outcome, then both...
Peripheral-Blood-Based PCR Assay to Identify Patients with Childhood Tuberculosis
Soo Sung Park, Byoung Moon Ahn, Eun Ryoung Kim, Il Soo Kim, Jae Jong Kim, Yu Jin Rha, Han Ho Park
Clin Exp Pediatr. 1997;40(6):841-849.   Published online June 15, 1997
Purpose : There is an urgent need for rapid and accurate diagnosis of childhood tuberculosis. Recently, developments in molecular biology have raised hopes about the possibilities of new strategies for tuberculosis diagnosis. Most of these methods have focused on the application of PCR to sputum samples from patients with suspected mycobacterial disease. We used a nested PCR to detect circuclating Mycobacterial tuberculosis DNA in...
The Therapeutic Effects of Dexamethasone Therapy in Neonate with Bacterial Meningitis
Eun Gyung Lee, Kook In Park, Min Soo Park, Moon Sung Park, Ran Namgung, Chul Lee, Dong Kwan Han
Clin Exp Pediatr. 1995;38(5):602-611.   Published online May 15, 1995
Purpose : In experimental models of meningitis and in children with meningitis, dexametha-sone has been shown to reduce meningeal inflammation and to improve the outcome of disea-se. We studied the effects of dexamethasone administration in neonates(<2 month-old) with b-acterial meningitis. Methods : We retrospectively reviewed the medical records of 30 neonates admitted to the nursery, the Yonsei University College of Medicine...
Case Report
An autopsy Case of Nonbacterial Thrombotic Endocarditis
Sun Hee Huh, Hae Yong Lee, Won Kyu Choi, Mee Kyung Namgoong, Jong Soo Kim, Mee Yon Cho
Clin Exp Pediatr. 1993;36(6):888-893.   Published online June 15, 1993
We experienced a case of nonbacterial thrombotic endocarditis in a 25-day-old male neonate, who was suffered from ASD, MR and congestive heart failure. He was died suddenly during recovery phase. The Post diagnosis was nonbacterial thrombotic endocarditis. We report with a brief review and its related literatures.
Original Article
The diagnostic significance of APR score in early detection of neonatal bacterial infection.
Ki Won Park, Kyeong Choi, Young Youn Choi, Tai Ju Hwang
Clin Exp Pediatr. 1991;34(9):1223-1230.   Published online September 30, 1991
An accurate and rapid diagnostic test is essential in the management of bacterial infection in neonates because they lack specific symptoms and the bacterial infections in neonates tends to have rapid progression and poor prognosis. As for the method, APR (acute phase reactants), a score measuring C-reactive protein (CRP), 상racid glycoprotein (이-AG) and Haptoglobin (Hp) by latex agglutination seems to be one of promising methods. In...
A clinical study on neonatal bacterial meningitis.
Yong Won Park, Jung Hwan Choi, Chong Ku Yun
Clin Exp Pediatr. 1991;34(6):763-770.   Published online June 30, 1991
Clinical courses of 12 neonates who were confirmed as neonatal bacterial meningitis by CSF culture or CSF latex agglutination test from January, 1986 to June, 1990, emphasizing on their complications and treatments, were evaluated. The results were summarized as follows; 1) The most common etiologic organism was E. coli (33.3%). 2) Two most common complications were ventriculitis (66.7%) and hydrocephalus (66.7%). 3) EVD with intraventricular antibiotics therapy was only...
A Case of Recurrent Bacterial Meningitis with CSF Rhinorrhea.
Dae Shik Kim, Jin Yong Lee, Chang Jun Coe, Jin Suk Suh
Clin Exp Pediatr. 1989;32(8):1161-1166.   Published online August 31, 1989
Recurrent bacterial meningitis is a rare disease which is associated with congenital or acquired anatomical defects of CNS and surround structures, or it may be due to parameningeal foci of infection, defects in immune response, and post-operative state of shunt procedure in hydrocephalus. We experienced the patient of recurrent bacterial meningitis with CSF rhinorrhea due to structural defect which was not defined exactly. We identified...
A Case of Recurrent Bacterial Meningitis due to Congenital Cribriform Plate Defect.
Hong Chul Lee, Jong Leam Choi, Wan Soeb Kim, Myung Ho Lee
Clin Exp Pediatr. 1989;32(3):412-417.   Published online March 31, 1989
One patient with a history of recurrent bacterial meningitis was examined with skull and sinus radiographs, routine cranial computed tomography and immunologic evaluation. None of these studies were diagnostic. Thin-section (1-2 mm) direct coronal computed cranial tomography demonstrated congenital cribriform plate defect. This patient was repaired surgically and no further meningitis has developed for 16 months
Clinical Observations of Meningitis.
Byoung Hoon Lee, Hyung Keun Nam, Myung Ik Lee, Keun Chan Sohn
Clin Exp Pediatr. 1989;32(2):180-190.   Published online February 28, 1989
The 267 cases of meningitis were observed at National Medical Center between Jan. 1st 1979 and May 31, 1986. The results were as follow; 1) In BM and TM sexual difference was not notice, but male was more in AM. 2) In BM infancy was the most common, but school age was common was AM. 3) Most cases developed during spring in BM and TM...
Cerebrospinal Fluid Lymphocytosis in Acute Bacterial Meningitis on Children.
Hong Kun Kim, Woo Gill Lee
Clin Exp Pediatr. 1988;31(6):707-714.   Published online June 30, 1988
Clinical and laboratory analysis of 78 cases of acute bacterial meningitis diagnosed by cere- brospinal (CSF) culture under 15 years old was made, retrospectively from Jan. 1973 to Dec. 1986, who were admitted to the Department of Pediatrics Hanyang University Hospital. The results analysed were as follows: 1) CSF lymphocytosis (more than 50% lymphocytes or mononuclear cells)occurred in 18 of 78 cases (23%) of bacterial meningitis. 2) There...
Case Report
A Case of Recurrent Bacterial Meningitis Secondary to the Defect of Stapes Footplate.
Soon Hee Eom, Joo Hong Cha, Byoung Soo Cho, Sa Jun Chung, Chang Il Ahn, Chang Il Cha
Clin Exp Pediatr. 1986;29(7):779-783.   Published online July 31, 1986
With the dramatic lowering the mortality rate of bacterial meningitis since the introduction of antibacterial agents, multiple attacks of bacterial meningitis no longer are a curiosity. So multiple attacks of bacterial meningitis may be the only indication of the existence of an abnormal communication between the nasopharynx or ear and the meningeal space and such a communication must be found. We...
A Case of Eosinophilic Granuloma with Recurrent Bacterial Meningitis associated with CSF Rhinorrhea.
Eung Deok Choi, Mee Kyung Namgoong, Seung Ha Yoo, Baek Keun Lim, Jong Soo Kim, Tae Seung Kim
Clin Exp Pediatr. 1986;29(2):209-214.   Published online February 28, 1986
We experienced a case of eosinophilic granuloma with multiple lesions on skull, ribs, vertebrae, tibia and pelvic bone. In addition, recurent bacterial meningitis was associated with CSF rhinorrhea probably due to osteolytic lesion of eosinophilic granuloma in the same patient. A brief review of literature was made.
Original Article
The Use of Pedialyte(R) RS(oral electrolyte solution) and Isomil(R) in the Treatment of Nonbacterial Acute Infantile Gastroenteritis.
Keun Soo Lee, Seung Jae Yang, Soo Jee Moon, Hahng Lee
Clin Exp Pediatr. 1985;28(4):330-339.   Published online April 30, 1985
40 Pediatric patients with mild to moderate dehydration due to nonbacterial acute infantile gastroenteritis were admitted to the study. On admission to the hospital, each patient was assigned at random either to the Pedialyte® RS+Isomil®(Group A), or to intravenous fluid+cow's milk-based formula (Group B). Each group consisted of 20 patients. There were no significant differences between the two group as...
A Clinical Observation on Neonatal Bacterial Meningitis.
Young Ju Lee, Bu Kwun Jung, Soon Ok Byun, Myung Hi Shin, Ji Sub Oh
Clin Exp Pediatr. 1983;26(9):872-883.   Published online September 30, 1983
A clinical observation was made on 80 cases of neonatal bacterial meningitis who were admitted to the department of Pediatrics at Wallace Memorial Baptist Hospital, Busan, Korea, during a 8 years period between Jan, 1, 1975 and Dec. 31, 1982. 1) There was no significant differences in annual incidence. The incidence of neonatal bacterial meningitis was 0.34% of total admissions in Ped. dept, and...
Clinical Study of C-Reactive Protein in Neonatal Bacterial Infections.
Kyung Shin Kim, Myung Sung Moon, Jin Choi, Keun Soo Lee
Clin Exp Pediatr. 1983;26(9):866-871.   Published online September 30, 1983
Bacterial infections, such as sepsis, meningitis, pneumonia and urinary tract infection are frequent causes of death during neonatal period. Further more clinical symptoms of neonatal infections are often quite vague and the illnesses unexpectedly progress rapidly. The causative organisms are detected with difficulty in many instances. Therefore a quick, simple and.reliable laboratory test is obviously needed for easy recognization of neonatal bacterial...
Cat-Scratch Disease.
Tai Gyu Whang, Hyun Gi Jung, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1982;25(3):283-288.   Published online March 31, 1982
We observed a case of cat-scratch disease who was an 18-month-old boy with the chief complaint of generalized enlargement of lymphnodes. Clinical manifestations and patholcgic findings of a lymphnode were presented in detail. The diagnosis of cat-scratch disease in this case was made according to the criteria proposed by Carithers et al. and Margileth. A brief review of literature was made.
Epidemiologic Study of Enterobacteriaceae Infection of Nursery Room.
Byung Zoo Choi, Hae Sook Kim, In Ho Kim, Myung Sook Lee, Churl Young Chung
Clin Exp Pediatr. 1981;24(6):525-534.   Published online June 15, 1981
We found enterobacteriaceae in throat culture of premature infants in our nursery who showed poor appetite, poor activity and irregular weight gain and was diagnosed as having respiratory distress syndrome and pneumonia from May 1980 to August 1980. At this time we also found enterobacteriaceae in throat cultures of three normal newborns whose each age was at 1 hr old,...
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