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Original Article
A Case of Congenital Hypoplastic Anemia.
Jae Wook Lee, Soon Ok Kang, Jee Sung Kim, Im Ju Kang, Seh Yoon Jeong
Clin Exp Pediatr. 1989;32(5):724-729.   Published online May 31, 1989
We observed a case of congenital hypoplastic anemia in a 6 months old female patient who was admitted because of severe anemia & failure to thrive and diagnosed through bone marrow aspiration. This patient had reticulocytopenia & increased M:E ratio (57.5:1). His hematologic improvement was followed by administration of prednisone. A brief review of related literature was made.
Cyclophosphamide-Induced Hemorrhagic Cystitis in Acute Lymphocytic Leukemia and Non-Hodgkin Lymphoma.
Young Seo Park, Il Soo Ha, Soon Ki Kim, Hae Il Jung, Yong Choi, Hyo Seop Ahn
Clin Exp Pediatr. 1989;32(5):665-669.   Published online May 31, 1989
We studied the cyclophosphamide-induced hemorrhagic cystitis in 72 cases of acute lymphocytic leukemia or Non-Hodgkin lymphoma, which had been treated at Seoul National University Children' s Hospital from June, 1985 to May, 1988 1) Among 72 cases treated with cyclophosphamide, 6 cases(12.8%) developed hemorrhagic cystitis in 47 cases of acute lymphocytic leukemia and 2 cases(8.0%) in 25 cases of Non-Hodgkin lymphoma. 2) The development of...
A Case of Congenital Megakaryoblastic Leukemia Accompanied by Down Syndrome Which was Diagnosed by Autopsy Findings.
Il Kyung Kim, Dong Beom lee, Jung Sik Min, Chang Hee Choi, Je Geun Chi
Clin Exp Pediatr. 1989;32(2):262-269.   Published online February 28, 1989
Many cases of acute megakaryonlastic leukemia have been reported in childhood or adults, but congenital form or the cases occuring in neonatal period is very rare throughout the world. In Korea only one case was reported previously by Chung et al in 1987. The authors experienced a case of congenital megakaryoblastic leukemia accompanied by Down' s syndrome, which was confirmed by autopsy and positive...
A Case of Testicular Tumor Metastasized to The Lung.
Jong Sik Kim, Dae Young Kim, Kang Ho Kim, In Kwyu Park, Young Bong Park, Chang Soo Ra
Clin Exp Pediatr. 1989;32(1):137-142.   Published online January 31, 1989
A 11/2 year old male child was admitted to the Department of Pedíatrics of Chosun University Hospital because of dyspnea and coughíng. on physical examination, intercostal and subcostal retraction were observed, and dullness and decreased breathing sound were auscultated on the right side chest. Seven months earlier, the patient developed a mass on the right side testis and has grown rapidly and was admitted to...
A Case of Child Desquamative Interstitial Pneumonia.
Woo Taek Kim, Hyoung Doo Lee, Yung Tak Lim, Hee Joo Jeon, Hee Joo Park, Chan Yung Kim
Clin Exp Pediatr. 1989;32(1):92-100.   Published online January 31, 1989
Desquamative interstitial pneumonia (DIP) is a variant of idiopathic interstitial pneumonias, but characteristicalIy has massive desquamation and proliferation of alveolar cells into the distal air space with minimal fibrosis of the alveolar wall. DIP seems to have better response to corticosteroid and benign prognosis than idiopathic interstitial pneumonia. We experienced one case of 6-year old girl who showed typical picture of DIF on lung...
Angioimmunoblastic Lymphadenopathy in a Child.
S J Lee, H S Lee, H S Kim, C M Kang, D S Kim
Clin Exp Pediatr. 1988;31(12):1669-1673.   Published online December 31, 1988
Angioimmunoblastic lymphadenopathy is a lymphoma like disorder consisting of generalized lymphadenopathy, hepatosplenomegaly, skin rashes, often associated with dysgammag- lobulinemia. We have experienced recently 3 year old female complaining of generalized lymphadenopthy, fever, hepatomegaly and hypergammaglobulinemia, and was proved as angioimmunoblastic lymphadenopathy histologically. Patient was treated with combined chemotherapy with COMP and responded well clinically in 4 months. The brief review of the literature was made.
Perforation of the Gastointestinal Tract in Infancy and Childhood.
S J Lee, Y S Kim, H D Cha, T C Kwon, C M Kang
Clin Exp Pediatr. 1988;31(12):1626-1632.   Published online December 31, 1988
Thirty-nine patients with perforations of the gastrointestinal tract proved by operation were presented. 35.9% of perforations were between the age of 6-10 year and 20.5% were Neonates. Male to female ratio was 2:1. The cardinal symptom of the perforation was abdominal pain in older child and abdominal distention in the neonates. Abdominal X-ray showed subphrenic free air shadow in 48.7% of the total cases. The subphrenic free...
The Abeominal Tuberculosis in Children.
Young Sik Kim, Jeong Hun Ha, Jeong Kee Seo
Clin Exp Pediatr. 1988;31(12):1594-1602.   Published online December 31, 1988
following results were obtained through the clinical review of 29 cases with the abdominal tuberculosis under the age of 15 years, who admitted to Seoul National University Hospital from January, 1977 to December, 1987. 1) Thirteen cases were patients with tuberculous peritonitis, 12 cases were patients with intestinal tuberculosis, and the remaining 4 cases were patients with both tuberculous peritonitis and intestinal tuberculosis. 2) The male to...
A Case of Intestinal Tuberculosis with Huge Retroperitoneal Tuberculous Lymphadenitis Simulating Neoplasm.
Yong Suk Kim, Dong Seok Choi, Keon Su Rhee, Young Hun Chung
Clin Exp Pediatr. 1988;31(10):1385-1389.   Published online October 31, 1988
Since the advent of effective antituberculous chomtherapy in the 1940s, the frequency and severity of intestinal tuberculosis have markedly decreased. But the incidence of tuberculous disease is still high in Korea. We have recently experienced a cases of intestinal tuberculosis with huge retroperitoneal tuberculous lymphadenitis simulating neoplasm in 2 year 3 month old female. The cases was reported with the brief review of literatures.
A Case of Mediastinal Tuberculous Lymphadenitis.
Hyung Ja Park, Mi Ja Yoon, Shinna Kim
Clin Exp Pediatr. 1988;31(10):1381-1384.   Published online October 31, 1988
A case of mediastinal tuberculous lymphadnitis in 5 year old male child was reported. Clinical symptoms were disappeared and chest CT findings showed very much improvement after administra- tion of Isoniazid, Rifampin and Prednisolone for 4 months. A brief review of literature was presented.
A Case of Spindle Cell Thymoma with Spinal Cord Compression.
Ki Hyeok Lee, Dong Joo Nah, Jong In Byun, Sang Min Seong, Kyung Tai Whang, Eun Deok Chang, Young Hee Jee
Clin Exp Pediatr. 1988;31(9):1237-1242.   Published online September 30, 1988
We experienced a case who presented symptoms of spinal cord compression in association with posterior mediastinal thymoma. A 2-year old female patient was admitted to the hospital for evaluation of gait difficulty and motor weakness of legs which aggravated during two weeks prior to admission. General physical, mental status examination and cranial nerve functions were within normal limits. Diffuse moderate weakness of the lower extremities...
Histiocytic Medullart Reticuloisis in Children.
Duck Kyu Kim, Jung Hyun Park, Ok Ji Hwang, Ja Ye Kim, Woo Kap Chung, Kye Sook Lee
Clin Exp Pediatr. 1988;31(9):1217-1224.   Published online September 30, 1988
Histiocytic medullary reticulosis (HMR) is a clinicopathologic syndrome characterized by its acute onset and relentless progression to death within a few months. Major clinical features are fever, wasting, generalized lymphadenopathy and hepatosplenomegaly. In the terminal stages, Jaundice, purpura, anemia and leukopenia are common. Cardinal pathologic features are diffuse proliferation of atypical, neoplastic, erythrophagocytic histiocytes and their precursors throughout the reticuloen- dothelial system. Here, we present 2...
Observation of Socail Background and Diesase Petterns of Children in an Institute for Adoption (the 2nd report).
Hong Hoon Lee, Myung Ik Lee, Soon Wha Kim, Don Hee Ahn, Keun Chan Sohn
Clin Exp Pediatr. 1988;31(9):1171-1182.   Published online September 30, 1988
A study was made to see the family background of abandonment and clinical and laboratory findings in an institute for foreign adoption. The results were compared to the previous report from the same institute. The results were as follows. 1) Girls were much more than boys in number with male to female ratio of 1:2.1 2) Concerning age distribution, the infant under one month of age was...
A Case of Acute Megakaryoblastic Leukemia in Infant with Down's Syndrome.
Jung Soon Whang, Soon hee Kim, Moon Ja Kim, Keun Lee, Je Geun Chi
Clin Exp Pediatr. 1988;31(8):1064-1070.   Published online August 31, 1988
Acute megakaryoblastic leukemia is an uncommonly recognized disorder that is characterized by rapidly progressive proliferation of atypical megakaryocytes and their precursor cells, and fatal course. Abnormalities in chromosome 21 may have a more than random relationship to acute megakaryoblastic leukemia. The authors reports a case of acute megakaryoblastic leukemia in a 2 month old female patient who was admitted for evaluation of hepatosplenomgaly. Multiple organ infiltration...
Statistical Assessment on Chromosomal Aberrations observed on Childhood.
Seong Ho Kim, Jeh Hoon Shin, Soo Jee Moon, Hahng Lee, KeunSoo Lee, Youl Hey Cho, Myung So Ryu, Young Kyun Paik
Clin Exp Pediatr. 1988;31(8):977-983.   Published online August 31, 1988
Chromosomal studies were carried out in 730 patients at the Dept, of Pediatrics and Genetics, Hanyang University Hospital, form December 1979 to April 1986. A statistical assessment was carried out in 244 cases who have chromosomal aberrations. The following results were obtained: 1) Chromosomal aberrations were observed in 244 cases among 730 cases, so the propotion of chromosomal aberrations was 33%. 2) Age distribution revealed 53% of chromosomal...
A Case of Cleidocranial Dysostosis with Leukemia.
Baik Lin eun, Si Hun Han, Young Sook Hong, Soon Kyum Kim
Clin Exp Pediatr. 1988;31(7):930-934.   Published online July 31, 1988
Cleidocranial dysostosis is a rare, inherited abnormality which affects the development of mem- bransous and cartilaginous bone. Authors report a case of cleidocranial dysostosis with leukemia in a 10 year old boy. The review of the literature was made briefly.
A Case of Mediastinal Gastroenteric Cyst.
Hong Ryang kil, Hye Suk Hong, Yang Won Lee, Jong Jin Seo, Young hun Chung, Seung Pyung Lim
Clin Exp Pediatr. 1988;31(7):924-929.   Published online July 31, 1988
Among heterogenous group of developmental anomalies known as enteric duplication, mediastinal gastroenteric cysts are rare and of outstanding diagnostic importance, because without definitive treatment they can be fatal. Unlike other mediastinal cysts they are almost never asymtomatic. The authors experienced a case of mediastinal gastroenteric cyst in 1 year 7 month-old female patient with chief complaint of abnormal mass density in chest X-ray. The...
A Case of Mucocutaneous Lymph Node Syndrome Complicated by Partial Intestinal Obstruction.
Dong Won Choi, Ki Sup Chung, Jin Suk Suh
Clin Exp Pediatr. 1988;31(6):796-802.   Published online June 30, 1988
Mucocutaneous lymph node syndrome was first described as a new clinical disease by Kawasaki in Japan in 1967. Recently, there have been numerous reports of this disease throughout the world and mucocutaneous lymph node syndrome has become familiar to the pediatrician. Complications previously described include coronary arteritis, carditis and gall bladder hydrops, aseptic meningitis and arthritis. We experienced 1 case of mucocutaneous lymph node syndrome...
Hypoplastic Left Heart Syndrome : Report of a Unique Survivor.
Hang Bo Cho, Seong Ho Kim, Ha Baik Lee, Kyu Hwang Rhee, Chong Moo Park
Clin Exp Pediatr. 1988;31(6):790-795.   Published online June 30, 1988
Hypoplastic left heart syndrome is a rare, and fatal congenital heart disease. Most of the patients with this syndrome die within the 1st month of life. Recently we experienced a hypoplastic left heart syndrome in a child who was unusually living without surgical intervention for 3 and half years. The unique clinical course might result from a number of favorable hemodynamic factors and intact...
Statistical Analysis of Pediatric Diseases in Korea.
Kyong Su Lee, Ki Sup Chung, Ki Yang Ryoo, Woo gill Lee, Sang Bum Lee, Se Jin Kang
Clin Exp Pediatr. 1988;31(6):678-690.   Published online June 30, 1988
Statistical analysis of pediatric diseases in patients admitted to the department of pediatrics in 34 hospitals having pediatric residency program for 2 years from Jan. 1985 to Dec. 1986 was underwent for the purpose of assessing the disease pattern in the pediatric aged people in Korea. The results obtained were as follows 1) Total number of inpatients was 112,309, of which 69,266 were male and...
A Case of Medistinal Lipoma.
Hung Sub Choi, Myung Ho Oh, Chang Hwi Kim, Sang Jhoo Lee, Yong Sik Lee
Clin Exp Pediatr. 1988;31(1):141-146.   Published online January 31, 1988
The mediastinal lipoma is a rare benign tumor. Since the original description by Fothergill in 1781, about 120 cases have been reported in literature. Of these, less than ten have been reported in children below the age of twelve. We experienced a case of mediastinal lipoma, in a 5 year old girl with mild dry cough. Chest X-ray showed a large, homogeneous soft tissue...
A Case of Sacrococcygeal teratoma complicated by hydronephrosis and hydroureter.
Joo Saeng Moon, Sung Ki Jin, Doo Sung Moon, Kyung Sook Cho, Jong Dae Cho, In Ki Sung, Bo Hyun Han
Clin Exp Pediatr. 1988;31(1):134-140.   Published online January 31, 1988
The authors experienced a case of benign cystic sacrococcygeal teratoma in a 2 month-old female infant. The cystic mass was located at presacral area without external presentation, causing left renal hydronephrosis and ureterectasis. Surgical excision of the mass was performed successfully. The literature regarding the subject was reviewed.
Liver Function Test in Congestive Heart Failure in Children.
Chan Yung Kim, Man Chul Ha
Clin Exp Pediatr. 1988;31(1):48-57.   Published online January 31, 1988
Clinical study was carried out on 149 congestive heart failure(CHF) cases of 873 heart disease patients admitted to the Department of Pediatics, Pusan National University Hospital from January 1980 to June 1987 and performed various diagnostic evaluations, especially liver function tests. The results obtained were as follows. 1) The congenital (CHD) and acquired (AHD) cause of heart disease were each 75.9% and 19.0% and the rest,...
A Case of Congenital Myeloblastic Leukemia Associated with Down's Syndrome.
Ho Jin Oh, Kee Hyoung Lee, Chang Sung Son, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(12):1468-1474.   Published online December 31, 1987
A 4 day old male patient was admitted to our hospital due to jaundice, poor feeding and abdominal distention. His clinical features and peripheral blood smear revealed congenital myeloblastic leuke- mia which confirmed by autopsy. Chromosome study showed 47, XY, +21 in Karyotype. We report this case with review of literatures.
A Case of Type A Niemann Pick Disease.
Hyo Nam Cho, Hong Jin Lee, Jae Won Song, Jung Hwan Choi, Hyung Ro Moon, Je Geun Ji, Myeong Hee Park
Clin Exp Pediatr. 1987;30(12):1461-1467.   Published online December 31, 1987
We experienced a case of type A Niemann Pick disease in 13 month female baby. She showed marked hepatosplenomegaly, developmental regression and apathy. Fundoscopic examination revealed a cherry red spot in the macula. Numerous foamy histiocyte were seen in bone marrow. Autopsy finding revealed that liver, spleen, thymus, lymph node, lung and brain were involved. Liver showed fatty change. Generalized muscular atrophy and patch...
A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
Clin Exp Pediatr. 1987;30(11):1282-1286.   Published online November 30, 1987
In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was associated with hypoplasia of the lungs and characteristic faces. Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter syndorme. We report a case...
A Case of Pneumocystis Carinii Pneumonia Associated with Cytomegalovirus Lung Infection.
K S Lee, Y O Lee, H J Park, M J Shin
Clin Exp Pediatr. 1987;30(11):1274-1281.   Published online November 30, 1987
Pneumocystis carinii pneumonia has been highly prevalent in prematurity, malnourished infants and immunosuppressed patients. Since 1981, it has been by far the commonest opportunistic infection in AIDS. We experienced a case of Pneumocystis carinii pneumonia associated with cytomegalovirus lung infection in a 3 months old malnourished female orphan. She had been suffered from chronic diarrhea, losing body weight 2 kg in a month prior...
A Clinical Study on Gastrointestinal Polyps in Infancy and Childhood.
Soo Kyoung Chang, Ki Sup Chung
Clin Exp Pediatr. 1987;30(10):1134-1142.   Published online October 31, 1987
Gastrointestinal polyps in infants and children are relatively rare, but they occur frequently enough to merit attention and consideration as a cause of chronic intermittent rectal bleeding of small amounts. Total 69 cases of gastrointestinal polyps under 15 years of age who had been admitted to Department of Pediatrics, Yonsei University College of Medicine for 11 years from January, 1975 to June, 1985 were...
Upper Gastrointestinal Fiberoptic Endoscopy in Children.
Dong Hyup Lee, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Il Min
Clin Exp Pediatr. 1987;30(8):868-873.   Published online August 31, 1987
We observed 63 cases ranging in age from 3 years to 15 years seen by gastrofibroscopy in Dept, of Int. Med. and Dept, of Ped. of Kyung hee Univ. Hospital from January 1980 to December 1985 and following results were obtained 1) The male to female ratio was about 1:1.17. The frequency of the age distribution was 1.6% below 5 years, 25.4% in 6-10 years...
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
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