Clinical and Experimental Pediatrics

Original Article

Myocardial atrophy in children with mitochondrial disease and Duchenne muscular dystrophy

Tae Ho Lee, Lucy Youngmin Eun, Jae Young Choi, Hye Eun Kwon, Young-Mock Lee, Heung Dong Kim, Seong-Woong Kang

Clin Exp Pediatr. 2014;57(5):232-239. Published online May 31, 2014

Purpose

Mitochondrial disease (MD) and Duchenne muscular dystrophy (DMD) are often associated with cardiomyopathy, but the myocardial variability has not been isolated to a specific characteristic. We evaluated the left ventricular (LV) mass by echocardiography to identify the general distribution and functional changes of the myocardium in patients with MD or DMD.

Methods

We retrospectively evaluated the echocardiographic data of 90 children with...

DOI: https://doi.org/10.3345/kjp.2014.57.5.232

Case Report

Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction

Ji Hyeun Song, Yeo Hyang Kim, Chun Soo Kim, Sang Lak Lee, Tae Chan Kwon

Clin Exp Pediatr. 2009;52(1):129-132. Published online January 15, 2009

We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiomegaly, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered...

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Original Article

Clinical Features of Isolated Noncompaction of the Ventricular Myocardium

Eun-Kyoung Moon, Hoon-Young Lee, Mea-Young Chang, Hong-Ryang Kil, Yong-Hun Chung

Clin Exp Pediatr. 2002;45(12):1528-1533. Published online December 15, 2002

Purpose : Isolated noncompaction of the ventricular myocardium(INVM) is one of the unclassified cardiomyopathies that is characterized by numerous, excessively prominent trabeculations, and deep intertrabecular recesses. We performed this study to evaluate the clinical features of INVM in children. Methods : The medical records of 10 patients with INVM were reviewed. We analyzed the clinical manifestations, hemodynamics, pattern of inheritance,...

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The Influence of the Preoperative Chronic Cyanosis on the Cardiac Troponin I in the Pediatric Cardiac Operation

Jinyoung Song, Sungkyu Lee, Jaeyoung Lee, Soojin Kim, Wooseup Shim

Clin Exp Pediatr. 2002;45(4):498-504. Published online April 15, 2002

Purpose : The purpose of this study was to evaluate the perioperative myocardial damage in pediatric congenital heart disease with the cardiac specific protein of cardiac troponin I(cTpn-I). Methods : All 25 pediatric patients who were diagnosed with tetralogy of Fallot or double outlet right ventricle were classified as group A(acyanotic, SaO2 >90%), group B(mildly cyanotic, SaO2 >80-90%) and group C(moderately...

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