| The Influence of the Preoperative Chronic Cyanosis on the
Cardiac Troponin I in the Pediatric Cardiac Operation |
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Jinyoung Song, Sungkyu Lee, Jaeyoung Lee, Soojin Kim, Wooseup Shim |
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Department of Pediatric, Sejong General Hospital, Pucheon, Korea |
| 지속적인 청색증에 노출된 선천성 심장병에서 수술 후 Cardiac Troponin I의 농도 변화 |
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송진영, 이성규, 이재영, 김수진, 심우섭 |
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부천세종병원 소아과 |
Correspondence:
Jinyoung Song, Email: amyjys@hanmail.net
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| Abstract |
Purpose
: The purpose of this study was to evaluate the perioperative myocardial damage in pediatric congenital heart disease with the cardiac specific protein of cardiac troponin I(cTpn-I).
Methods
: All 25 pediatric patients who were diagnosed with tetralogy of Fallot or double outlet right ventricle were classified as group A(acyanotic, SaO2 >90%), group B(mildly cyanotic, SaO2 >80-90%) and group C(moderately cyanotic, SaO2 <80%). The control group D was consisted of 10 patients with ventricular septal defects who were operated in the same period. We measured preoperative hemoglobin, preoperative and postoperative(24 and 72 hour) arterial oxygen saturation, cTpn-I and creatine kinase(CK-MB).
Results
: Total 25 patients were subdivided into 6 of group A, 12 of group B and 7 of group C. The concentrations of preoperative cTpn-I were 0.23?.12 ng/mL in group A, 0.25?.12 ng/mL in group B, 0.26?.13 ng/mL in group C. And the concentrations of cTpn-I in postoperative 24 hour were 10.04?.28 ng/mL in group A, 12.50?.86 ng/mL in group B, 12.55?.90 ng/mL in group C. Which revealed cTpn-I in group C was higher than that of the another less cyanotic groups. In addition, the concentration of cTpn-I of group C in postoperative 72 hour was higher than any other groups. The concentration of cTpn-I in postoperative 72 hour was statistically correlated with that in postoperative 24 hour and preoperative arterial oxygen saturation(P=0.001).
Conclusion
: Preoperative chronic cyanosis can influence on the postoperative concentration of cTpn-I in pediatric cardiac patients, which means impairment on the postoperative myocardial recovery. |
| Key Words:
Cyanosis, Cardiac Troponin I, Myocardium, Cardiac operation |
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