Korean Journal of Pediatrics 2009;52(1):129-132.
Published online January 15, 2009.
Changes in N-terminal pro-B-type natriuretic peptide in a neonate with symptomatic isolated left ventricular noncompaction
Ji Hyeun Song1, Yeo Hyang Kim1, Chun Soo Kim1, Sang Lak Lee1, Tae Chan Kwon1
1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
1Department of Pediatrics, Keimyung University School of Medicine, Daegu, Korea
신생아기에 발견된 단독 심실 비치밀화증 1예에서 관찰된 NT pro-BNP의 변화
송지현1, 김여향1, 김천수1, 이상락1, 권태찬1
1계명대학교 의과대학 소아과학교실
1계명대학교 의과대학 소아과학교실
1계명대학교 의과대학 소아과학교실
1계명대학교 의과대학 소아과학교실
1계명대학교 의과대학 소아과학교실
Correspondence: 
Yeo Hyang Kim, Email: kimyhped@hanmail.net
Abstract
We describe here our experience with a neonate presenting with cyanosis, grunting, and cardiomegaly, who was diagnosed with isolated left ventricular noncompaction (IVNC) by echocardiography. The patient had high levels of N-terminal pro-B-type natriuretic peptide (NT pro-BNP) and symptoms of heart failure including poor feeding and tachypnea. During the period in which NT pro-BNP levels steadily increased, the patient suffered sudden cardiac arrest despite heart failure management. Following cardiopulmonary resuscitation, cardiac arrest was resolved, NT pro-BNP levels decreased, and all symptoms showed improvement. We consider that assessment of NT pro-BNP with cardiac functional analysis using echocardiography could help in the prediction of disease progress in IVNC.
Key Words: Newborn, Myocardium, Natriuretic peptide, Brain


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