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Immunohistochemical Studies on Neuroendocrine Markers in Malignant Neuronal Tumors (Neuroblastoma and Ganglioneuroblastoma) in Children

Woo Yeong Chung, Sun Kyung Lee

Clin Exp Pediatr. 1992;35(10):1377-1388. Published online October 15, 1992

The authors studied 24 cases of malignant neuronal tumors, 14 neuroblastomas and 10 ganglioneuroblastomas, immunohistochemically, using antibodies to neuroendocrine markers including neuron specific enolase (NSE), somatostatin, chromogranin, β-endorphin, and adrenocorticotrophic hormone (ACTH). The tissue specimens were obtained by biopsy or autopsy at Pusan National University Hopital and Pusan Paik Hospital from 1980 to 1989. The positive reactivity of markers in...

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