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Sobhy E. Kotb (Kotb SE)

1 Article

Original Article

Gastroenterology

Thyroid disturbances in children treated with combined pegylated interferon-alpha and ribavirin for chronic hepatitis C

Yasser K. Rashed, Fatma A. Khalaf, Sobhy E. Kotb

Clin Exp Pediatr. 2020;63(2):52-55. Published online September 27, 2019

Web of Science 4 Crossref 4

Background: Immunomodulatory properties of interferon (IFN) have been documented. It may induce autoimmune diseases such as autoimmune thyroiditis with hypo- or hyperthyroidism. In addition, it may impair thyroid hormone synthesis through affecting iodide organification in thyroid gland.
Purpose: The aim of this study was to describe thyroid function tests disturbances in children with chronic hepatitis C (CHC) receiving pegylated interferon-alpha (PEG...

DOI: https://doi.org/10.3345/kjp.2018.07150

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