Clinical and Experimental Pediatrics

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So-ra Lee (Lee SR)

2 Articles

Case Report

A Case of Mosaic Tetraploidy

Ji-hwan Choi, Ju-a Lee, So-ra Lee, Yeon-kyun Oh, Hee-sub Rhee, Jeong-joong Kim, See-sung Choi

Clin Exp Pediatr. 2000;43(9):1274-1278. Published online September 15, 2000

Tetraploidy of human chromosome(92, XXYY) has been described very rarely. Liveborn infant with tetraploidy was reported in only 17 cases(complete 7 cases, mosaicism 10 cases) in the world, and no cases have been reported in Korea. The diploid-tetraploid mosaicism could arise during the early mitosis of the zygote : In one blastomeric cell, the chromosomes replicate but the cytoplasm does...

Original Article

The Protective Effect of Vitamin E and Desferrioxamine on Cultured Cerebral Neurons of Neonatal Mouse Damaged by Ischemic Condition

So-ra Lee, Yeon-kyun Oh, Seung-taek Park

Clin Exp Pediatr. 1999;42(10):1426-1433. Published online October 15, 1999

Purpose : Perinatal asphyxia is an important cause of neurologic morbidity. Experiments in animal models of hypoxic-ischemic brain injury demonstrate that brain damage starts during hypoxia-ischemia. In order to evaluate the ischemic condition-induced neurotoxic effect in view of oxi- dative stress, we examined the cytotoxic effect in cultured cerebral neurons of neonatal mouse. Methods : Dissociated cell cultures were prepared...

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