- Original Article
- The usefulness of soluble transferrin receptor in the diagnosis and treatment of iron deficiency anemia in children
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Se Hoon Yoon, Dong Sup Kim, Seung Taek Yu, Sae Ron Shin, Du Young Choi
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Clin Exp Pediatr. 2015;58(1):15-19. Published online January 31, 2015
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Purpose Soluble transferrin receptor (sTfR) is a truncated extracellular form of the membrane transferrin receptor produced by proteolysis. Concentrations of serum sTfR are related to iron status and erythropoiesis in the body. We investigated whether serum sTfR levels can aid in diagnosis and treatment of iron deficiency anemia (IDA) in children. MethodsNinety-eight patients with IDA were enrolled and were classified according to... |
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- Relationship between iron deficiency anemia and febrile convulsion in infants
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Youn Soo Jun, Ho Il Bang, Seung Taek Yu, Sae Ron Shin, Du Young Choi
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Clin Exp Pediatr. 2010;53(3):392-396. Published online March 15, 2010
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Purpose : The association between iron deficiency anemia and febrile convulsion in infants has been examined in several studies with conflicting results. Therefore, the authors aimed to evaluate the precise relationship involved.
Methods : In this case-control study, the authors assessed 100 children with a diagnosis of febrile convulsion, aged between 9 months and 2 years, during January 2007 to... |
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- Anti-tumor effect of new compound, 127, through the induction of apoptosis
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Ki Hwan Baek, A Lum Han, Sae Ron Shin, Chun Mae Jin, Young Wook Yoon, Seung Taek Yu, Jong Duk Kim, Du Young Choi
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Clin Exp Pediatr. 2009;52(6):696-700. Published online June 15, 2009
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Purpose : We screened more than 350 compounds with an endoperoxide ring structure in search of an anti-leukemic drug and found that compound 127 (c-127) could induce significant cytotoxicity in HL-60 cells. In this study, we investigated the molecular mechanisms of compound 127-induced antitumor activity on HL-60 cells.
Methods : HL-60 cells were cultured in Rosewell Park Memorial Institute 1640... |
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- Clinical features of vaccination-associated thrombocytopenic purpura in children
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Wan Soo Lee, Seung Taek Yu, Sae Ron Shin, Du Young Choi
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Clin Exp Pediatr. 2008;51(6):610-615. Published online June 15, 2008
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Purpose : Idiopathic thrombocytopenic purpura (ITP) is a relatively common hematological disease in children. It generally occurs after exposure to a common viral infection episode; however, it may occasionally follow immunization with measles, measles-mumps-rubella (MMR), hepatitis B (HBV), influenza, diphtheria tetanus-pertussis (DTP), or chickenpox vaccines. In this study, the incidence, clinical characteristics, and treatment outcome of vaccination-associated ITP were investigated... |
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