Clinical and Experimental Pediatrics

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Kyung Shin Lee (Lee KS)

1 Article

Original Article

Allele Distribution and Frequency of Human Surfactant Protein-A1 in Korean Neonates

Kyung Shin Lee, Young Hee Kim, Jung Su Suk, Jung Ho Ko, Ook Joon Yoo, In Kyu Lee, Myung Ho Oh, Chong Woo Bae

Clin Exp Pediatr. 2002;45(12):1497-1502. Published online December 15, 2002

Purpose : We evaluated allele frequencies and distribution of surfactant protein A1(SP-A1) in Korean neonates in order to estimate prevalence of RDS to find out new SP-A alleles, and to establish new steroid therapy. Methods : Genomic DNA was extracted from 100 neonates and served as a template in PCR for genotype analysis. SP-A gene-specific amplications and gene-specific allele determinations were...

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