- Editorial
- Neurobehavior
- Impact of coronavirus disease 2019 on children’s health
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Joon Won Kang
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Clin Exp Pediatr. 2022;65(10):498-499. Published online September 16, 2022
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· Coronavirus disease 2019 (COVID-19) has had an enormous impact on mental health and other aspects of children’s health.
· The prevalence of anxiety, depression, and posttraumatic stress disorder in children and adolescents have increased in the COVID-19 era.
· Cooperation among parents, guardians, academic societies, and the government is needed to maintain the mental health of children and adolescents. |
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- Review Article
- Neurology
- Is it really a seizure? The challenge of paroxysmal nonepileptic events in young infants
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Seung Yeon Jung, Joon Won Kang
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Clin Exp Pediatr. 2021;64(8):384-392. Published online September 18, 2020
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Paroxysmal nonepileptic events (PNE) comprise of a variety of nonepileptic behaviors and are divided into various types. A more accurate diagnosis is possible by examining the video clip provided by the caregiver. In infants, physiologic PNE accounts for the majority of the PNE. It is important to exclude epilepsy, for which blood tests, electroencephalography, and imaging tests can facilitate differential... |
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- Original Article
- Neurology
- Outcome of ultrasonographic imaging in infants with sacral dimple
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Jin Hyuk Choi, Taekwan Lee, Hyeok Hee Kwon, Sun Kyoung You, Joon Won Kang
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Clin Exp Pediatr. 2018;61(6):194-199. Published online June 25, 2018
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Purpose Sacral dimples are a common cutaneous anomaly in infants. Spine ultrasonography (USG) is an effective and safe screening tool for patients with a sacral dimple. The aim of this study was to determine the clinical manifestations in patients with an isolated sacral dimple and to review the management of spinal cord abnormalities identified with USG. MethodsWe reviewed clinical records and collected... |
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- Long-term prenatal stress increases susceptibility of N-methyl-D-aspartic acid-induced spasms in infant rats
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Hyeok Hee Kwon, Taekwan Lee, Jinpyo Hong, Dong Woon Kim, Joon Won Kang
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Clin Exp Pediatr. 2018;61(5):150-155. Published online May 28, 2018
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Purpose Infantile spasms, also known as West syndrome, is an age-specific epileptic seizure. Most patients with this condition also exhibit delayed development. This study aimed to determine the effect of long-term prenatal stress on susceptibility to infantile spasms. MethodsWe subjected pregnant rats to acute or chronic immobilization stress. Resulting offspring received N-methyl-D-aspartic acid (15 mg/kg, intraperitoneally) on postnatal day 15, and their... |
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- Clinical manifestations of headache in children younger than 7 years
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Bu Seon Kang, Jinsun Lee, Jin Hyuk Choi, Hyeok Hee Kwon, Joon Won Kang
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Clin Exp Pediatr. 2018;61(11):355-361. Published online September 16, 2018
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Purpose: Headache is a common symptom during childhood. It is usually persistent and requires special care. This study aimed to identify the characteristics of headache in children <7 years of age.
Methods: We reviewed 3 years of clinical files on children <7 years of age with a chief complaint of headache.
Results: This study included 146 children (66 males, 80 females; mean... |
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- Case Report
- Chronic inflammatory demyelinating polyneuropathy in children: a report of four patients with variable relapsing courses
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Soo Jin Chang, Ji Hyun Lee, Shin Hye Kim, Joon Soo Lee, Heung Dong Kim, Joon Won Kang, Young Mock Lee, Hoon-Chul Kang
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Clin Exp Pediatr. 2015;58(5):194-198. Published online May 22, 2015
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Chronic inflammatory demyelinating polyneuropathy (CIDP) is a chronically progressive or relapsing symmetric sensorimotor disorder presumed to occur because of immunologic antibody-mediated reactions. To understand the clinical courses of CIDP, we report variable CIDP courses in children with respect to initial presentation, responsiveness to medical treatment, and recurrence interval. Four patients who were diagnosed with acute-onset and relapsing CIDP courses at... |
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- Original Article
- Efficacy of levetiracetam in refractory childhood epilepsy
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Keon Su Lee, Joon Won Kang
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Clin Exp Pediatr. 2010;53(4):571-578. Published online April 15, 2010
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Purpose : To evaluate the efficacy and safety of levetiracetam adjunctive therapy for reducing the rate of seizure frequency in children with intractable pediatric epilepsy.
Methods : We reviewed the medical records of 86 patients with intractable pediatric epilepsy who visited our hospital between March 1989 and February 2009. Levetiracetam was included in the previous anticonvulsant regimen for at least 6... |
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- Clinical significance of loss of p16 protein by immunohistochemical
staining in acute lymphoblastic leukemia
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Hye Young Jin, Kyoung In Kang, Sun Young Kim, You Sook Youn, Joon Won Kang, Deog Yeon Jo, Kye Chul Kwon, Kyung Duk Park
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Clin Exp Pediatr. 2008;51(1):73-77. Published online January 15, 2008
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Purpose : p16 gene, mapped to the 9p21 chromosomal region, has emerged as a candidate tumor suppressor gene in human neoplasm. It is an inhibitor of cyclin-dependent kinase and inhibits Rb phosphorylation. In a variety of tumors including childhood acute lymphoblastic leukemia (ALL), deletion and/or mutation of the p16 gene has been found. Despite their high frequency, the prognostic importance... |
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- Effect of intravenous deferoxamine in multiply transfused patients
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Sang Min Oh, Joon Won Kang, Sun Young Kim
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Clin Exp Pediatr. 2007;50(12):1225-1230. Published online December 15, 2007
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Purpose : Multiple transfusions in patients with chronic anemia can result in excessive iron deposition in tissues and organs. Effective iron chelation therapy in chronically transfused patients can only be achieved when iron chelators remove sufficient amounts of iron equivalent to those accumulated in the body from transfusions, thus leading to maintain body iron load at a non-toxic level. This... |
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