Clinical and Experimental Pediatrics

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Jinpyo Hong (Hong J)

1 Article

Original Article

Neurology

Long-term prenatal stress increases susceptibility of N-methyl-D-aspartic acid-induced spasms in infant rats

Hyeok Hee Kwon, Taekwan Lee, Jinpyo Hong, Dong Woon Kim, Joon Won Kang

Clin Exp Pediatr. 2018;61(5):150-155. Published online May 28, 2018

Crossref 3

Purpose

Infantile spasms, also known as West syndrome, is an age-specific epileptic seizure. Most patients with this condition also exhibit delayed development. This study aimed to determine the effect of long-term prenatal stress on susceptibility to infantile spasms.

Methods

We subjected pregnant rats to acute or chronic immobilization stress. Resulting offspring received N-methyl-D-aspartic acid (15 mg/kg, intraperitoneally) on postnatal day 15, and their...

DOI: https://doi.org/10.3345/kjp.2018.61.5.150

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