- Guideline
- Endocrinology
- 2017 Clinical practice guidelines for dyslipidemia of Korean children and adolescents
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Jung Sub Lim, Eun Young Kim, Jae Hyun Kim, Jae-Ho Yoo, Kyung Hee Yi, Hyun Wook Chae, Jin-Ho Choi, Ji Young Kim, Il Tae Hwang; the Committee of Dyslipidemia of Korean Children and Adolescents on behalf of Korean Society of Pediatric Endocrinology (KSPE)
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Clin Exp Pediatr. 2020;63(12):454-462. Published online November 25, 2020
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Question: How are children and adolescents with dyslipidemia treated and managed in Korea?
Finding: 2017 guidelines recommend to measure nonfasting non-HDL-C as a screening test and introduce new diet methods: Cardiovascular Health Integrated Lifestyle Diet (CHILD)-1, CHILD-2-low-density lipoprotein cholesterol, and CHILD-2-triglyceride. Statin is the only drug approved in children older than 10 years.
Meaning: New clinical practice guidelines for treating and managing dyslipidemia of Korean children and adolescents are provided. |
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- The relationship between adiponectin, leptin, insulin, insulin-like growth factor and IGF binding protein-3 in cord blood and neonatal anthropometric parameters
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Hai Jung Cho, Ji Young Kim, Me Jin Kim, Il Tae Hwang, Hae Ran Lee
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Clin Exp Pediatr. 2008;51(7):722-728. Published online July 15, 2008
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Purpose : This study was designed to examine the effects of adiponectin, leptin, insulin, insulin-like growth factor (IGF)-I and IGF binding protein (BP)-3 levels in cord blood on weight, length, and adiposity at birth in healthy term infants. In addition, we evaluated the mechanism to change the hormone levels in appropriate for gestational age (AGA) during the first month.
Methods :... |
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- Relationship between cord blood level of IL-12 in
preterm newborns and development of wheezing
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Hyo Jung Yu, Eun Ae Park, Ji Young Kim, Soo Jin Cho, Young Ju Kim, Hye Sook Park, Eun Hee Ha
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Clin Exp Pediatr. 2008;51(7):754-759. Published online July 15, 2008
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Purpose : Abnormal activation patterns of Th1/Th2-cells have been suggested to increase the prevalence of allergic diseases. Prevention is regarded as an important corner stone in the management of allergic diseases. In this study, we have investigated the relationship between cord blood levels of IL-4, IL-10, and IL-12 in preterm newborns and the development of allergic respiratory diseases in infancy
Methods... |
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- Leptin, adiponectin, interleukin-6 and
tumor necrosis factor- in obese adolescents
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Joo Hyun Gil, Jung Ah Lee, Ji Young Kim, Young Mi Hong
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Clin Exp Pediatr. 2008;51(6):597-603. Published online June 15, 2008
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Purpose : Obesity is associated with insulin resistance. Insulin resistance and the presence of pro-inflammatory mediators are thought to cause a state of vascular endothelial dysfunction, an abnormal lipid profile, hypertension, and vascular inflammation. These chronic inflammatory responses, which are characterized by abnormal cytokine production, lead to activation of a pro-inflammatory signaling pathway. Leptin is an important mediator of inflammatory... |
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- The neuroprotective effect of mycophenolic acid via anti-apoptosis in perinatal hypoxic-ischemic brain injury
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Ji Young Kim, Seung Ho Yang, Sun Hwa Cha, Ji Yeun Kim, Young Chae Jang, Kwan Kyu Park, Jin Kyung Kim, Hai Lee Chung, Eok Su Seo, Woo Taek Kim
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Clin Exp Pediatr. 2007;50(7):686-693. Published online July 15, 2007
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Purpose : Mycophenolic acid (MPA), the active metabolite of mycophenolate mofetil (MMF), is a potent inhibitor of inosine-monophosphate dehydrogenase (IMPDH), a new immunosuppressive drug used. It was reported that MPA protected neurons after excitotoxic injury, induced apoptosis in microglial cells. However, the effects of MPA on hypoxic-ischemic (HI) brain injury has not been yet evaluated. Therefore, we examined whether MPA... |
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- Cord blood IL-10, IL-12 in preterm newborns as predictors of
respiratory distress syndrome and bronchopulmonary dysplasia
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Jee Yoon Park,, Ji Young Kim, Soo Jin Cho, Young Ju Kim, Hye sook Park, Eun Hee Ha, Eun Ae Park
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Clin Exp Pediatr. 2007;50(3):248-254. Published online March 15, 2007
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Purpose : Inflammation plays a major role in the pathogenesis of RDS and BPD in the immature lung. We investigated the possible role of IL-10 and IL-12 in the cord blood of preterm newborns with RDS or BPD.
Methods : Forty preterm newborns whose mothers received antenatal care at Ewha Womans University Mokdong Hospital between January 2003 to June 2005, and... |
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- Pulmonary Function Test and Body Composition Analysis in Obese Children
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Jee Seon Shin, Ji Hye Park, Ji Young Kim, Su Jung Kim, Young Mi Hong
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Clin Exp Pediatr. 2005;48(6):588-593. Published online June 15, 2005
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Purpose : Obesity is associated with disturbances of ventilatory functions in adults. But few studies have evaluated the pulmonary complications of obesity in the pediatric population. The purpose of this study is to clarify the effects of obesity on pulmonary function and body composition in obese children.
Methods : Forty seven obese children whose ages ranged from nine to twelve... |
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- Chest X-ray Findings and Serum Tumor Necrosis Factor-α Levels in Patients with Kawasaki Disease
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Ji Young Kim, Jung Hyun Kwon, Kyung Hyo Kim, Jung Hyun Yu, Young Mi Hong
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Clin Exp Pediatr. 2005;48(5):534-538. Published online May 15, 2005
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Purpose : Kawasaki disease(KD) is a multisystemic inflammatory vasculitis of unknown etiology. Many complications other than cardiovascular involvement have been recognized in KD. However, there have been few reports published concerning involvement of the lungs in this disease. The purpose of this study was to examine the relationship between serum TNF-α, the degree of coronary artery dilatation and chest X-ray(CXR)... |
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- Smoking Adolescents' Acquisition of Cigarettes and Status of Proof of Age
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Hee Ra Kim, Ji Young Kim, Gee Hyung Lee, Ji Tae Choung, Sang Hee Park
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Clin Exp Pediatr. 2005;48(4):363-368. Published online April 15, 2005
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Purpose : The aim of this study is to identify where and how adolescents acquire cigarettes and how many were asked for identification while purchasing cigarettes.
Methods : This study was conducted in 2003; participants were 2,200 students in middle and high schools, aged from 13 to 18 years old(males 1,098; females 1,102) in Ansan, Korea. The questionnaire assured them of... |
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- The Effectiveness of Intravenous Immunoglobulin for Clinically Suspected Neonatal Sepsis
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Hyun Jung Na, Ji Young Kim, Gyeong Hoon Lee, Jun Hwa Lee, Eun Jin Choi, Jin Kyung Kim, Hai Lee Chung, Woo Taek Kim
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Clin Exp Pediatr. 2005;48(11):1187-1192. Published online November 15, 2005
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Purpose : The purpose of this study is to determine the effectiveness of intravenous immunoglobuin (IVIG) administration in fullterm neonates having clinically suspected neonatal sepsis.
Methods : Forty full-term neonates admitted to the neonatal intensive care unit with clinically suspected neonatal sepsis, who had at least two positive diagnostic criteria were enrolled. Twenty neonates were enrolled into the IVIG arm and... |
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- Applicability of the "Questionnaire on Risk Factors Associated with Obesity in Adolescents" in School-Based Screening to Prevent Life Style Disease as a Result of Complicated Adolescent Obesity
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Yoon Hee Shim, Ji Young Kim, Soo Jeung Lee, Su Jin Cho, Whaan Kuck Yeong, Young Mi Hong
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Clin Exp Pediatr. 2004;47(12):1266-1272. Published online December 15, 2004
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Purpose: The prevalence of obesity and complications related to obesity among Korean adolescents were reviewed. To prevent obesity related complications in adolescents, the applicability of the "Questionnaire on risk factors associated with obesity in adolescents" as an assessment and management guideline was evaluated.
Methods: Weight, height, blood pressure and serum lipid and glucose level of 7,265 high school students in Seoul... |
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- Case Report
- A Case of Pseudohypoparathyroidism in a Premature Infant
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Jong Il Yang, Jang Won Seo, Ji Young Kim
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Clin Exp Pediatr. 2003;46(10):1032-1035. Published online October 15, 2003
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In pseudohypoparathyroidism as reported by Albright in 1942, the parathyroid gland can normally synthesize and secrete parathyroid hormone(PTH). Pseudohypoparathyroidism has a similar biochemical finding with hypoparathyroidisms like hypocalcemia and hyperphosphatemia due to target tissue resistance to PTH. Administered PTH does not raise the serum levels of calcium and urinary phosphate. PTH activates G-protein in peripheral tissue and adenylate cyclase through... |
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- Original Article
- The Effect of Angiotensin Converting Enzyme Gene Polymorphism in Children with
Henoch-Schonlein Purpura Nephritis
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Chang Woo Ha, Ji Young Kim, Jeong Nyeo Lee, Jeong Hwa Lee, Woo Yeong Chung
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Clin Exp Pediatr. 2002;45(7):884-890. Published online July 15, 2002
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Purpose : Henoch-Schonlein purpura(HSP) nephritis has been reported to vary from 25 to 50% among HSP patients and is a common cause of chronic glomerulonephritis in children. In our study, we evaluated the distribution and the association of the Insertion/Deletion(I/D) polymorphism of angiotensin converting enzyme(ACE) gene with clinical manifestations, particularly proteinuria in children with HSP nephritis, compared with that in... |
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- Renal Anomalies in Children with Turner Syndrome
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Ji Young Kim, Sun Young Hong, Young Mi Park, Yong Hoon Park, Woo Yeong Chung
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Clin Exp Pediatr. 2002;45(7):891-895. Published online July 15, 2002
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Purpose : The prevalence of renal anomalies in Turner syndrome(TS) has been reported to vary from 33% to 60%. The purpose of this study was to clarify the true incidence of renal malformations in Korean TS.
Methods : We evaluated 33 patients with Turner syndrome diagnosed by karyotype in Inje University Busan Paik hospital and Youngnam University from January 1995.... |
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- A Clinical Study of Antithrombin Ⅲ Therapy for Disseminated Intravascular Coagulation in Neonates
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Ji Young Kim, Cheong Nyen Kim, Myoung Jae Chey, Cheol Young Cheong
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Clin Exp Pediatr. 1998;41(5):593-598. Published online May 15, 1998
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Purpose : The purpose of this study is to evaluate the clinical effect of antithrombin Ⅲ concentrates in disseminated intravascular coagulation(DIC) of neonates.
Methods : We reviewed the clinical records of 11 newborn patients who had been admitted and diagnosed as DIC at the neonatal intensive care unit of Sanggye Paik Hospital from November, 1995 to September, 1996.
Results : There were... |
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