- Editorial
- Neonatology (Perinatology)
- Impacts of maternal COVID-19 during pregnancy on neonatal health and epidemiology
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Jae Woo Lim
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Clin Exp Pediatr. 2024;67(3):149-151. Published online December 28, 2023
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Newborns born to mothers infected with coronavirus disease 2019 (COVID-19) should be closely monitored for respiratory disorders, such as transient tachypnea of the newborn, regardless of their COVID-19 test results. Further research is required of the development of infants born to mothers with COVID-19. The trends in Korea's birth rate and infant mortality rates have not been significantly affected by COVID-19. |
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- Original Article
- Neonatology (Perinatology)
- Mortality of very low birth weight infants by neonatal intensive care unit workload and regional group status
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Sung-Hoon Chung, Chae Young Kim, Yong-Sung Choi, Myung Hee Lee, Jae Woo Lim, Byong Sop Lee, Ki-Soo Kim; the Korean Neonatal Network
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Clin Exp Pediatr. 2024;67(11):619-627. Published online September 12, 2024
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Question: How do structural and staffing characteristics of neonatal intensive care units (NICUs) influence the mortality rates of very low birth weight infants (VLBWIs)?
Findings: NICUs with higher staffing levels, particularly with more neonatologists, and those offering advanced care levels were associated with lower mortality rates. Additionally, regional disparities were observed, with some areas demon-strating significantly higher survival rates.
Meaning: Adequate staffing and equitable regional distribution of medical resources are crucial for improving survival outcomes in VLBWIs. Efforts to enhance NICU staffing and address regional healthcare disparities are essential for optimizing care quality and reducing mortality in this vulnerable population. |
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- Gastroenterology
- Clinical manifestation of Campylobacter enteritis in children
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Joon Yeol Bae, Dong Hyuk Lee, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Young Hwa Song, Jung Min Yoon
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Clin Exp Pediatr. 2018;61(3):84-89. Published online February 28, 2018
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Purpose Timely antibiotic therapy in selected cases of diarrhea associated with bacterial infections can reduce the duration and severity of illness and prevent complications. The availability of a predictive index before identification of causative bacteria would aid in the choice of a therapeutic agent. MethodsThe study included patients admitted to the pediatrics unit at Konyang University Hospital for acute inflammatory diarrhea from... |
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- Cardiology
- The improvement of right ventricular function after adenotonsillectomy in children with obstructive sleep apnea
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Dong Yeop Kim, Kyung Ok Ko, Jae Woo Lim, Jung Min Yoon, Young Hwa Song, Eun Jeong Cheon
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Clin Exp Pediatr. 2018;61(12):392-396. Published online October 26, 2018
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Purpose: Adenotonsillar hypertrophy (ATH) that causes upper airway obstruction might lead to chronic hypoxemic pulmonary vasoconstriction and right ventricular (RV) dysfunction. We aimed to evaluate whether adenotonsillectomy (T&A) in children suffering from obstructive sleep apnea (OSA) due to severe ATH could improve RV function.
Methods: Thirty-seven children (boy:girl=21:16; mean age, 9.52±2.20 years), who underwent T&A forsleep apnea due to ATH, were... |
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- Case Report
- Genetics and Metabolism
- Interstitial deletion of 5q33.3q35.1 in a boy with severe mental retardation
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Jin Hwan Lee, Hyo Jeong Kim, Jung Min Yoon, Eun Jung Cheon, Jae Woo Lim, Kyong Og Ko, Gyung Min Lee
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Clin Exp Pediatr. 2016;59(Suppl 1):S19-S24. Published online November 30, 2016
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Constitutional interstitial deletions of the long arm of chromosome 5 (5q) are quite rare, and the corresponding phenotype is not yet clearly delineated. Severe mental retardation has been described in most patients who present 5q deletions. Specifically, the interstitial deletion of chromosome 5q33.3q35.1, an extremely rare chromosomal aberration, is characterized by mental retardation, developmental delay, and facial dysmorphism. Although the... |
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- Gastroenterology
- Granular cell tumor of the esophagus in an adolescent
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Ji Sun Lee, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Young Jin Kim, Jang Sin Son, Jung Min Yoon
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Clin Exp Pediatr. 2016;59(Suppl 1):S88-S91. Published online November 30, 2016
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Esophageal granular cell tumor (GCT) is a rare neoplasm originating from the Schwann cells of the submucosal neuronal plexus. Histology is the gold standard for its diagnosis. Endoscopic resection or surgical excision should be considered, depending on the potential for malignancy. Here, we report a case of an esophageal GCT in an adolescent. A 12-year-old boy presented with a 1-year... |
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- Original Article
- Cardiology
- Age-adjusted plasma N-terminal pro-brain natriuretic peptide level in Kawasaki disease
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Heul Jun, Kyung Ok Ko, Jae Woo Lim, Jung Min Yoon, Gyung Min Lee, Eun Jung Cheon
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Clin Exp Pediatr. 2016;59(7):298-302. Published online July 31, 2016
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Purpose Recent reports showed that plasma N-terminal pro-brain natriuretic peptide (NT-proBNP) could be a useful biomarker of intravenous immunoglobulin (IVIG) unresponsiveness and coronary artery lesion (CAL) development in Kawasaki disease (KD). The levels of these peptides are critically influenced by age; hence, the normal range and upper limits for infants and children are different. We performed an age-adjusted analysis of plasma... |
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- Fecal calprotectin concentration in neonatal necrotizing enterocolitis
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Jung Min Yoon, Ju Yi Park, Kyung Ok Ko, Jae Woo Lim, Eun Jeong Cheon, Hyo Jeong Kim
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Clin Exp Pediatr. 2014;57(8):351-356. Published online August 25, 2014
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Purpose Among the many factors associated with acute intestinal mucosal infection, numerous studies have proposed the usefulness of fecal calprotectin. The aim of this study was to evaluate the usefulness of fecal calprotectin in the diagnosis of necrotizing enterocolitis (NEC). MethodsWe collected 154 stool samples from 16 very low birth weight and premature newborns at the Konyang University Hospital neonatal intensive care... |
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- Case Report
- A pediatric case of Bickerstaff's brainstem encephalitis
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Ju Yi Park, Kyong Og Ko, Jae Woo Lim, Eun Jung Cheon, Jung Min Yoon, Hyo Jeong Kim
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Clin Exp Pediatr. 2014;57(12):542-545. Published online December 31, 2014
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Bickerstaff's brainstem encephalitis is characterized by ophthalmoplegia, ataxia, and disturbance of consciousness. It is similar to Miller Fisher syndrome, a variant of Guillain-Barre syndrome, in that they share features such as ophthalmoplegia and ataxia. The difference is that patients with Bickerstaff's brainstem encephalitis have impaired consciousness, whereas patients with Miller Fisher syndrome have alert consciousness and areflexia. Here, we report... |
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- Original Article
- Effect of adenotonsillar hypertrophy on right ventricle function in children
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Jin Hwan Lee, Jung Min Yoon, Jae Woo Lim, Kyung Og Ko, Seong Jun Choi, Jong-Yeup Kim, Eun Jung Cheon
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Clin Exp Pediatr. 2014;57(11):484-488. Published online November 30, 2014
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Purpose Chronic upper airway obstruction causes hypoxemic pulmonary vasoconstriction, which may lead to right ventricle (RV) dysfunction. Adenotonsillar hypertrophy (ATH) is the most common cause of upper airway obstruction in children. Therefore, we aimed to evaluate RV function in children with ATH. MethodsTwenty-one children (male/female, 15/6; mean age, 92.3¡¾39.0 months; age range, 4-15 years) with ATH and 21 healthy age- and gender-matched... |
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- Effect of early postnatal neutropenia in very low birth weight infants born to mothers with pregnancy-induced hypertension
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Yang Hee Park, Gyung Min Lee, Jung Min Yoon, Enn Jung Cheon, Kyung Ok Ko, Yung Hyuk Lee, Jae Woo Lim
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Clin Exp Pediatr. 2012;55(12):462-469. Published online December 20, 2012
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Purpose In this study, we aimed to investigate the perinatal clinical conditions of very low birth weight (VLBW) infants born to mothers with pregnancy-induced hypertension (PIH) focusing on the effects of early postnatal neutropenia. MethodsWe reviewed the medical records of 191 VLBW infants who were born at Konyang University Hospital, between March 2003 and May 2011. We retrospectively analyzed the clinical characteristics... |
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- Review Article
- The changing trends in live birth statistics in Korea, 1970 to 2010
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Jae Woo Lim
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Clin Exp Pediatr. 2011;54(11):429-435. Published online November 30, 2011
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Although Korean population has been growing steadily during the past four decades, the nation is rapidly becoming an aging society because of its declining birth rate combined with an increasing life expectancy. In addition, Korea has one of the lowest fertility rates in the world due to fewer married couples, advanced maternal age, and falling birth rate. The prevalence of... |
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- Development and language problems in children of immigrant marriages
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Jae Woo Lim
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Clin Exp Pediatr. 2009;52(4):417-421. Published online April 15, 2009
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The number of international marriages in South Korea has drastically increased since the year 2000, and among these, the proportion of couples with a Korean husband and foreign wife accounts for more than 70%. At the same time, the number of children resulting from an international marriage has also risen dramatically; this tendency is especially evident in preschool children below... |
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- Case Report
- A case of Kawasaki disease preceding a retropharyngeal abscess
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Hee Ok Park, Jae Woo Lim, Eun Jung Cheon, Kyung Ok Ko
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Clin Exp Pediatr. 2008;51(5):542-545. Published online May 15, 2008
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Epidural hematoma (EDH) is relatively rare in newborn infants and frequently associated with instrumental deliveries or other complications during labor and delivery. Although surgical evacuation has been the most common therapy, many other procedures have been suggested. Although many epidural hematomas require surgical evacuation rather than non-surgical management, the conservatiob or aspiration of hematoma have been attempted. In the case... |
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- Original Article
- Association of apolipoprotein E polymorphisms with serum lipid
profiles in obese adolescent
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Jung Min Yoon, Jae Woo Lim, Eun Jung Cheon, Kyoung Og Ko
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Clin Exp Pediatr. 2008;51(1):42-46. Published online January 15, 2008
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Purpose : Apolipoprotein E (Apo E) plays a major role in lipoprotein metabolism and lipid transport. Many investigators have described that Apo E polymorphisms is one of the most important genetic determinants for cardiovascular disease. The purpose of this study was to evaluate the association between Apo E polymorphisms and serum lipid profiles in obese adolescent.
Methods : We measured... |
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- Correlation of inhalant MAST on chronically coughing children
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Jung Min Yun, Eui Jung Roh, Jae Woo Lim, Eun Jung Choen, Kyoung Og Ko, Young Hyuk Lee
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Clin Exp Pediatr. 2006;49(6):643-647. Published online June 15, 2006
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Purpose : Recently, incidences of chronic cough with allergic disease have been increased. The identification of specific allergens for chronically coughing children is significant for diagnosis, proper treatment and prevention. The aim of this study was to identify significant contributors for sensitization in chronically coughing children.
Methods : A total of 106 children, aged 1-6 years, visiting for chronic cough(>3 weeks),... |
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- Change of early atherosclerotic markers in obese children
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Eui Jung Roh, Jung Min Yoon, Jae Woo Lim, Eun Jung Cheon, Kyoung Og Ko
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Clin Exp Pediatr. 2006;49(4):368-374. Published online April 15, 2006
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Purpose : The prevalence of obesity in children is increasing rapidly. Epidemiologic studies suggest that obesity induced atherosclerosis may start in childhood. We investigated whether obese children show early abnormalities of the arterial wall and endothelial dysfunction.
Methods : Thirty-eight obese children(14-16 years old of age, male, body mass index 29.40¡¾3.18 kg/m2) and forty-five age and sex-matched healthy control children(body... |
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- Original Article
- The Effect of Massage on Premature Infants
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Hee Sook Son, Jae Woo Lim, Kyuchul Choeh, Chang Soo Ra, Hark Hee Kim
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Clin Exp Pediatr. 2000;43(8):1046-1051. Published online August 15, 2000
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Purpose : To determine the effects of massage therapy on growth, development, hormones, immune
function, hepatic function, hematopoietic function and sleep pattern of preterm infants.
Methods : Thirty-one preterm infants of less than 35 weeks gestational age, who were admitted
to Eulji Medical College Hospital Neonatal Intensive Care Unit between August 1998 and May
1999, and were in the state without mechanical ventilation or... |
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- Infantile Hypertrophic Pyloric Stenosis Treated with Intravenous Atropine Sulfate
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Jae Woo Lim, Hee Sook Son, Kye Shik Shim, Kyu Chul Choeh, Tae Il Han
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Clin Exp Pediatr. 2000;43(6):763-768. Published online June 15, 2000
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Purpose : The pharmacologic effect of atropine on HPS can be considered to control pyloric muscle spasm. Therefore, we studied the effects of intravenous atropine sulfate on the clinical course of HPS, and periodically observed the ultrasonographic appearance of the pyloric muscles after atropine treatment.
Methods : From April 1998 to May 1999, 14 infants who were diagnosed with HPS were... |
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- Case Report
- A Case of Megacystis Microcolon Intestinal Hypoperistalsis Syndrome
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Jae Woo Lim, Jong Su Shin, Kyuchul Choeh, Chang Su Na, Tae Il Han
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Clin Exp Pediatr. 2000;43(2):278-282. Published online February 15, 2000
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Megacystis Microcolon Intestinal Hypoperistalsis(MMIH) Syndrome is a rare cause of functional neonatal bowel obstruction, characterized by hypoperistalsis, narrow distal ileum and colon, and bladder distension. We report a case of MMIH syndrome and review the literature. The patient was born after 34 weeks of gestation with marked abdominal distension. Her birth weight was 2,830g with 276ml of urine drained by... |
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