- Case Report
- A Successful Transplant of HLA-3 Loci
Mismatched Umbilical Cord Blood into a Patient with
Acute Myeloid Leukemia from an Unrelated Donor
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Byoung Chul Kwon, Kyung Mi Shin, Sung Chul Won, Chuhl Joo Lyu, Chang Hyun Yang, Hyun Ok Kim
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Clin Exp Pediatr. 2002;45(7):912-916. Published online July 15, 2002
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Cord blood is a useful source of allogeneic hematopoietic stem cells for bone marrow reconstitution. The number of umbilical cord blood transplants is increasing worldwide. In this a case 15- month-old boy with acute myeloid leukemia was treated with umbilical cord blood transplant from an HLA-3 loci mismatched unrelated donor. Granulocyte recovery greater than 500/mm3 occurred at day 49, and... |
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- A Case of Neonatal Alloimmune Thrombocytopenia Related to HLA Antibody
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Mi Seon Lee, Hyeon-Soo Lee, Hyun Ok Kim
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Clin Exp Pediatr. 2001;44(12):1454-1458. Published online December 15, 2001
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Neonatal alloimmune thrombocytopenia(NAIT) is a very rare disease caused by maternal alloantibodies` response to neonatal platelet antigens. Because the most common cause of NAIT is incompatibility for platelet-specific antigens, NAIT cases due to anti-HLA antibodies are very exceptional. The patient was a second born female. She had no petechia or purpura at birth. But her platelet count was 55,000/mm3 and... |
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- Original Article
- The Effects of RU 41.740, a Glycoprotein Extract from Klebsiella pneumoniae, on Peripheral Blood Mononuclear Cells
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Moon Kyu Kim, Dong Soo Kim, Hyun Ok Kim
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Clin Exp Pediatr. 1992;35(8):1066-1072. Published online August 15, 1992
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RU 41.740 is extract of Klebsiella pneumoniae K2O1 stain with immunomodulatory properties. It was composed of two glycoproteins, each being 31 KD and 33 KD in their molecular weight, on SDS-PAGE analysis. RU 41.740 was observed to augment cell mediated immunity of human peripheral blood mononulear cells measured by tritiated thymidine uptake method. Maximal augmentation was observed after 72 hours... |
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