- Original Article
- Immunology
- Serum bactericidal activity against meningococcus in patients with systemic lupus erythematosus
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Soyoung Lee, Kyung-Hyo Kim, Ji Hyen Lee, Han Wool Kim
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Clin Exp Pediatr. 2025;68(5):362-369. Published online January 13, 2025
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Question: What is the level of immunity against meningococcal infections in patients with systemic lupus erythematosus (SLE) under the age of 19, and is vaccination against meningococcus necessary for these patients, given their susceptibility to infections due to immunosuppressive treatments and disease characteristics?
Finding: Although some of our study patients exhibited serum bactericidal activity against meningococci, most remained seronegative.
Meaning: These findings suggest that patients with SLE who are at risk of meningococcal infection receive appropriate vaccinations. |
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- Editorial
- Infection
- Beyond COVID-19: meeting the challenge of evolving pediatric invasive group A streptococcal disease
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Han Wool Kim
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Clin Exp Pediatr. 2025;68(12):971-973. Published online November 26, 2025
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Pediatric for invasive group A Streptococcus has resurged globally with increasing severity and toxin-mediated presentations. Beta-lactams remain the first-line treatment, but linezolid has emerged as a safe alternative in cases refractory to β-lactams. Early intravenous immunoglobulin use may improve outcomes in severe streptococcal toxic shock syndrome cases, while C-reactive protein and procalcitonin aid early risk stratification. Integrating global surveillance and individualized therapy is crucial in the postpandemic era. |
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- Review Article
- Infection
- Epidemiology and clinical features of coronavirus disease 2019 in children
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Soo-Han Choi, Han Wool Kim, Ji-Man Kang, Dong Hyun Kim, Eun Young Cho
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Clin Exp Pediatr. 2020;63(4):125-132. Published online April 6, 2020
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Coronavirus disease-2019 (COVID-19), which started in Wuhan, China, in December 2019 and declared a worldwide pandemic on March 11, 2020, is a novel infectious disease that causes respiratory illness and death. Pediatric COVID-19 accounts for a small percentage of patients and is often milder than that in adults; however, it can progress to severe disease in some cases. Even neonates... |
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- Original Article
- Body composition by bioelectrical impedance analysis in children below 7 years old
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Jiyoung Jung, Han Wool Kim, Tae Hyun Kim, Young Mi Hong
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Clin Exp Pediatr. 2010;53(3):341-348. Published online March 15, 2010
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Purpose : Body composition is important to define and manage obesity and undernutrition. Obesity is a significant health problem with medical and psychological consequences for children and adolescents. Body composition analysis (BIA) is a simple, rapid, noninvasive, and reproducible technique. However, comparative analysis of body composition has not been done in young children below 7 years old. The aim of... |
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