- Case Report
- Immunology
- A novel BTK gene mutation, c.82delC (p.Arg28 Alafs*5), in a Korean family with X-linked agammaglobulinemia
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Jeongeun Lee, Minhee Rhee, Taek Ki Min, Hae In Bang, Mi-Ae Jang, Eun-Suk Kang, Hee-Jin Kim, Hyeon-Jong Yang, Bok Yang Pyun
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Clin Exp Pediatr. 2016;59(Suppl 1):S49-S52. Published online November 30, 2016
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X-linked agammaglobulinemia (XLA) is a hereditary humoral immunodeficiency that results from Bruton’s tyrosine kinase (BTK) gene mutations. These mutations cause defects in B-cell development, resulting in the virtual absence of these lymphocytes from the peripheral circulation. Consequently, this absence leads to a profound deficiency of lg all isotypes, and an increased susceptibility to encapsulated bacterial infections. A 15-month-old Korean boy... |
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- Original Article
- Serogroup and Antimicrobial Resistance of
Streptococcus pneumoniae Isolated from Oropharynx in
Children Attending Day Care Center
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Kyung Hyo Kim, Jong Eun Lee, Il Tae Whang, Kyung Ha Ryu, Young Mi Hong, Gyoung Hee Kim, Keun Lee, Eun-Suk Kang, Ki-Sook Hong
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Clin Exp Pediatr. 2002;45(3):346-353. Published online March 15, 2002
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Purpose : Penicillin- and multidrug-resistant S. pneumoniae poses a serious threat to clinicians because the rate of resistance of S. pneumoniae to penicillin in Korea has surged up to the world's highest level. This study was performed to assess the carriage rate, serogroups and antimicrobial susceptibility of S. pneumoniae isolated from oropharynx in children.
Methods : From March to July 1998,... |
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