- Original Article
- Statistical Analysis of 1,000 Cases of Kawasaki Disease Patients Diagnosed at a Single Institute
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Dae Hwan Hwang, Kyoung Mi Sin, Kyong Min Choi, Jae Young Choi, Jun Hee Sul, Dong Soo Kim
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Clin Exp Pediatr. 2005;48(4):416-424. Published online April 15, 2005
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Purpose : To find the risk factors associated with coronory artery lesions, non-responsiveness to intravenous immunoglobulin(IVIG) treatment, and recurrences in Kawasaki disease patients.
Methods : We retrospectively analyzed 1,000 Kawasaki disease patients who were admitted to Yonsei University Medical Center from September 1990 to December 2003. We compared between responder and non-responder groups to IVIG treatment as well as between relapsed... |
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- Expression of Toll-like Receptor-2 on the Peripheral Blood Monocytes in Kawasaki Disease Patients
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Dae Hwan Hwang, Jung Woo Han, Kyung Min Choi, Kyung Mi Shin, Dong Soo Kim
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Clin Exp Pediatr. 2005;48(3):315-320. Published online March 15, 2005
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Objective : Toll like receptor(TLR) is known to be involved in innate immunity. Many microbial antigens stimulate TLR, and as a result of intracellular signal transduction, they activate nuclear factor-kB which produces diverse inflammtory cytokines. Until now, many research topics in Kawasaki disease focused on cytokine increasement. In this study, we aim to reveal TLR increasement which might be associated... |
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- Effect of a Flavon Extracted from Artemisia absinthium on Collagen Induced Arthritis in Mice
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Kyong Min Choi, Dae Hwan Hwang, Kyung Mi Shin, Do-Young Yoon, Dong Soo Kim
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Clin Exp Pediatr. 2004;47(6):677-684. Published online June 15, 2004
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Purpose : In this study, a possible suppressive effect of a flavon extracted from Artemisia absinthium on a mouse collagen-induced arthritis (CIA) model was investigated.
Methods : DBA/1 mice were injected intradermally with emulsified chicken type II collagen. Three weeks after immunization, a flavon was introduced p.o. everyday. Clinical incidences of arthritis and arthritis index were measured. Measurement of anti-collagen antibodies... |
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