Clinical and Experimental Pediatrics

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2 Articles

Original Article

Association between macrophage migration inhibitory factor gene and growth differentiation factor 15 gene polymorphisms and circulating levels with respiratory distress syndrome among preterm neonates

Ali Helmi Bakri, Mohammed H. Hassan, Khaled Abdalla Abd-Elbaseer, Mahmoud Abo -Alhassan Sayed, Ahmed Alamir Mahmoud Abdallah, Eman Ahmed Abd-Elmawgood

Background: In preterm newborns, neonatal respiratory distress syndrome (RDS) is among the main causes of respiratory failure and mortality. However, the effect of macrophage migration inhibitory factor (MIF) on neonatal developmental lung disease is not well documented in the literature. Moreover, little is known about the effects of growth differentiation factor-15 (GDF-15) on lung maturity in preterm infants.
Purpose: To evaluate...

DOI: https://doi.org/10.3345/cep.2025.00416 [Accepted]

Adenosine deaminase and interleukin-1 receptor antagonist genetic polymorphisms among obese children with versus without metabolic dysfunction–associated fatty liver disease

Hala M. Sakhr, Mohammed H. Hassan, Azza Mohamed Taha, Ali Helmi Bakri

Background: Metabolic disorder–associated fatty liver disease (MAFLD) in children is an emerging global health concern, particularly in terms of obesity and metabolic disturbances. Inflammation plays a crucial role in the pathogenesis of MAFLD, with adenosine deaminase (ADA) and interleukin-1 receptor antagonist (IL-1Ra) being potential contributors.
Purpose: This study aimed to assess the association between ADA G22A and IL-1Ra single...

DOI: https://doi.org/10.3345/cep.2025.00731 [Accepted]

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Treatment targeting pediatric inflammatory bowel disease-associated anemia: experience from a single tertiary center

Role of neutrophil elastase in predicting infection among children with chemotherapy-induced febrile neutropenia

Artificial Intelligence in Pediatric Healthcare: current applications, potentials and implementation considerations

Effect of postoperative enteral protein supplementation on nitrogen balance in critically ill children

Adenosine deaminase and interleukin-1 receptor antagonist genetic polymorphisms among obese children with versus without metabolic dysfunction–associated fatty liver disease

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