Clinical and Experimental Pediatrics

Original Article

Adolescence Medicine

Relationship between inflammatory biomarkers and insulin resistance in excess-weight Latin children

Mariano Nicolás Aleman, María Constanza Luciardi, Emilce Romina Albornoz, María Cristina Bazán, Adela Victoria Abregú

Clin Exp Pediatr. 2024;67(1):37-45. Published online December 21, 2023

Question: What is the prevalence of insulin resistance (IR) in excess-weight Latin children, and can proinflammatory biomarkers predict it?
Finding: IR prevalence was elevated and tumor necrosis factor- α, interleukin-6, monocyte chemoattractant protein- 1, soluble CD40 ligand, and high-sensitivity C-reactive protein levels were increased in excess-weight Latin children. However, none predicted IR status.
Meaning: These inflammatory biomarkers were unable to predict IR status. Therefore, further investigations are necessary.

DOI: https://doi.org/10.3345/cep.2022.01382

Review Article

Adolescence Medicine

The impacts of exercise on pediatric obesity

Ronald J. Headid III, Song-Young Park

Clin Exp Pediatr. 2021;64(5):196-207. Published online August 4, 2020

Web of Science 17 Crossref 17

Pediatric obesity contributes to the development of vascular dysfunction and metabolic and cardiovascular diseases which have all been shown to track into adulthood, increasing the risk of early mortality. Early exercise intervention is critical for combating obesity-related comorbidities and the optimal exercise prescription has yet to be well documented. Exercise prescriptions to combat pediatric obesity should incorporate both aerobic and muscle-strengthening exercises with an emphasis on long-term adherence.

DOI: https://doi.org/10.3345/cep.2020.00997

Original Article

Adolescence Medicine

Serum alanine aminotransferase levels are closely associated with metabolic disturbances in apparently healthy young adolescents independent of obesity

Ki Eun Kim, Kyung Suk Baek, Sol Han, Jung Hyun Kim, Youn Ho Shin

Clin Exp Pediatr. 2019;62(2):48-54. Published online November 23, 2018

Crossref 2

Purpose: Liver metabolism plays a pivotal role in the development of metabolic disorders. We aimed to investigate the clinical and laboratory risk factors associated with alanine aminotransferase (ALT) levels in young adolescents from an urban population in Korea. Methods: A population of 120 apparently healthy adolescents aged 12–13 years was included in the cross-sectional design study; 58 were overweight or obese...

DOI: https://doi.org/10.3345/kjp.2018.06639

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