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Original Article
A Case of Thrombotic Thrombocytopenic Purpura in Childhood.
Dong Kun Hyun, Jung Bae Lee, Chang Hyun Yang, Kir Young Kim
Clin Exp Pediatr. 1988;31(4):511-518.   Published online April 30, 1988
Thrombotic thrombocytopenic purpura is clinically characterized by microangiopathic hemolytic anemia, thrombocytopenia, fever, renal disorder and transient bizarre neurological symptoms. Its essential histological lesion consists of numerous complete or, more often, incomplete occlusions of the arterioles and capillaries by hyaline material. We have experienced a case of thrombotic thrombocytopenic purpura in infancy. The patient was a one year and 4 month-old who complains petechiae on the...
A Clinical and histopathological Studies of congenital Extrahepatic Biliary Atresia.
Kweon Ha Son, Ki Sup Chung, Euh Ho Whang, Chan Il Park
Clin Exp Pediatr. 1988;31(4):436-445.   Published online April 30, 1988
A clinical assessment of the 30 patients with extrahepatic biliary atresia who were admitted to the Department of Pediatrics and pediatric Surgery, Yonsei University College of Medicine from January, 1979 to January, 1987 was performed. In 21 patients who underwent hepatic portoenterostomy, the relationship between outcome and surgery was analyzed. Finally, collelations between lonterm prognosis and the histopathology of biopsied liver tissue, postoperative bile...
A Case of Acute Hepatic Porphyria.
Young Cheal Han, Sin Hang Joo, Jin Han Kang, Byung Churl Lee
Clin Exp Pediatr. 1988;31(2):253-257.   Published online February 28, 1988
Acute hepatic porphyria may be an inborn error of metabolism characterized biochemically by the excessive hapatic over-production and urinary excretion of porphyrin precursors and clinically by episode of acute neuro-visceral dysfunction. Acute porphyria is very rare in childhood. We experienced a case of acute hepatic porphyria in childhood age, confirmed by characterized clinical features of neuro-visceral dysfunction and biochemical findings in blood and urine...
A Study on Minimal Change Nephrotic Syndrome in Children.
Yong Choi, Hong Jin Lee, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1988;31(2):220-226.   Published online February 28, 1988
To assess the clinical significance of histopathologic variants of minimal change nephrotic syn- drome (MCNS) by light microscopic findings, 148 biopsy proven MCNS patients, who were admitted to Seoul National University Hospital between the period from January 1976 to December 1986, were analyzed according to clinical findings, steroid responsiveness, and follow up status in relation to the pathologic variants. The followings are summary and conclusion. 1) Significantly...
A Case of Sacrococcygeal teratoma complicated by hydronephrosis and hydroureter.
Joo Saeng Moon, Sung Ki Jin, Doo Sung Moon, Kyung Sook Cho, Jong Dae Cho, In Ki Sung, Bo Hyun Han
Clin Exp Pediatr. 1988;31(1):134-140.   Published online January 31, 1988
The authors experienced a case of benign cystic sacrococcygeal teratoma in a 2 month-old female infant. The cystic mass was located at presacral area without external presentation, causing left renal hydronephrosis and ureterectasis. Surgical excision of the mass was performed successfully. The literature regarding the subject was reviewed.
A Case of Congenital Subglottic Stenosis.
Ho Taek Kim, Pyung Kil Kim, Ki Hyun Park
Clin Exp Pediatr. 1988;31(1):119-123.   Published online January 31, 1988
We experienced a case of congenital subglottic stenosis in a male baby of 2 month old. He surffered from respiratory difficulties since 40 days after birth. Initially, he had been considered as a stridor because of the symptom of upper airway obstruction did not improved for 4 months, so we started to assess the lesion of subglottic area since 15 days after admission,...
Non-Hemolytic Hereditary Ellitocytosis born of Asymptomatic Carrier state of Hereditary Elliticytosis.
Hae Joon Park, In Soon Ahn, Baek Keun Lim, Young Uh, Kyung Won Lee
Clin Exp Pediatr. 1988;31(1):113-118.   Published online January 31, 1988
Hereditary elliptocytosis is characterized by elliptically shaped erythrocytes in peripheral blood and known to be transmitted as an autosomal dominant trait, but in some cases, inherited recessively. The clinical and hematologic expressions are variable range from healthy person with normal red cell morphology to severe hemolytic anemia. Recently, the authors experienced all three offsprings shown non-hemolytic hereditary el- liptocytosis, whose parents were healthy persons with...
A Case of Congenital Myeloblastic Leukemia Associated with Down's Syndrome.
Ho Jin Oh, Kee Hyoung Lee, Chang Sung Son, Hyun Keum Lee
Clin Exp Pediatr. 1987;30(12):1468-1474.   Published online December 31, 1987
A 4 day old male patient was admitted to our hospital due to jaundice, poor feeding and abdominal distention. His clinical features and peripheral blood smear revealed congenital myeloblastic leuke- mia which confirmed by autopsy. Chromosome study showed 47, XY, +21 in Karyotype. We report this case with review of literatures.
A Case of Congenital Hepatic Fibrosis with Hypersplenism.
Hye Suk Hong, Yang Won Lee, Keon su Rhee, Young Hun Chung
Clin Exp Pediatr. 1987;30(12):1456-1460.   Published online December 31, 1987
Congenital hepatic fibrosis is a relatively rare disease of liver in children and young adults, manifesting a heredofamilial tendency, that is characterized by hepatosplenomegaly, protal hypertension and frequent renal involvement. A generalized portal and interlobular fibrosis of liver are characteristic finding on microscopy, with relative preservation of hepatocyte and liver function. Recently, we have experienced a case of congenital hepatic fibrosis in a...
Clinical Bacteriologic Study of Serratia Marcescens Septicemia.
Hyo Sook Hong, Wan Seob Kim, Oh Kyung Lee, Myung Ho Lee
Clin Exp Pediatr. 1987;30(12):1409-1418.   Published online December 31, 1987
We experienced an outbreak of Serratia marcescens septicemia during a 2-month-10-day period (Apirl the 10th, 1985-June the 6th, 1985) in the Chonju Presbyterian medical center, pediatric ward. The clinical and bacteriological features of 22 patients with septicemia were described. There were 25 bacterial isolates from 22 patients. Twenty cases of 22 patients recovered, while 2 patients died, both premature infants. This indicated the seriousness...
A Case of Potter Syndrome with Bilateral Polycystic Kidneys.
Chun Hwa Lee, Jung Hwan Choi, Yong Choi, Chong Ku Yun, Yeon Lim Suh, Je G Chi, Son Moon Shin
Clin Exp Pediatr. 1987;30(11):1282-1286.   Published online November 30, 1987
In 1946, Potter described a series of 20 cases of infants in whom bilateral absence of the kidneys was associated with hypoplasia of the lungs and characteristic faces. Afterwards it has been known that any condition that causes significant reduction in urine formation or excretion will result in oligohydramnios accounts for many of the nonrenal features of Potter syndorme. We report a case...
A Case of Mucocutaneous Lymph Node Syndrome Complicated by Aseptic Meningitis, Hydrops of the Gallbladeder and Dilatation of the Coronary Arteries.
Ho Jin Lee, Sung Sook Cho, Hyung Sik Moon, Hong Kue Lee, Soon Il Lee, Young Seok Lee
Clin Exp Pediatr. 1987;30(11):1259-1264.   Published online November 30, 1987
We experienced 1 case of mucocutaneous lymph node syndrome complicated by aseptic meningitis, hydrops of the gallbladder and dilatation of the coronary arteries in 2 year 8 month old female infant. Her clinical synptoms, laboratory data and clinical courses were presented with brief review of the literatures. This baby admitted because of high fever and vomiting for 6 days. She had injection of...
The Effect of Hepatitis B Vaccination on Newborns of Hepatitis B Carrier Mothers.
Ho Taek Kom, Pyung Kil Kim, Chang Ho Hong, Chul Lee
Clin Exp Pediatr. 1987;30(11):1228-1235.   Published online November 30, 1987
The transmission of hepatitis B virus (HBV) from carrier mothers to their infants is a serious problem in many countries and the transmission rate is reported to be as high as 60%. The best preventive method of perinatal transmission is hepatitis B immune globulin (HBIG) which confers a passive immunity and HB vaccine which confers an active immunity. However, the exact dosage and the...
Plasma Renin Acivity in Children with Acute Glomerulonephritis and Nephrotic Syndrome.
Oh Kyun Kwon, Young Hun Chung
Clin Exp Pediatr. 1987;30(11):1213-1220.   Published online November 30, 1987
This is a study on plasma renin acitivity (PRA) which was obtanined from the patients with acute glomerulonephritis or nephrotic syndrome and normotensive control group admitted in Chungnam National University Hospital from Oct. 1985 to Aug. 1986 to confirm any differences of PRA between groups and to establish their influencing factors. The results were as follows; 1) PRA of noimal children in preschool age (3.49 ±0.98...
Clinical Observation and Study for Cerebrospinal Fluid Protein Levels in Aseptic Meningitis.
D H Chee, M I Lee, S H Kim, K C Sohn
Clin Exp Pediatr. 1987;30(10):1107-1114.   Published online October 31, 1987
Observation for clinical findings and laboratory findings, especially for cerebrosipinal fluid protein level has been done in 57 cases of aseptic meningitis who had been admitted to pediatric dept, of National Medical Center from Jan. ’81 to May ’85. The results were as follows; 1) The ratio of male to female was 1.7:1, and the cases were distributed relatively evenly through ...
Case Report
A Case of Autoimmune Hemolytic Anemia Associated with Acute Viral Hepatitis B.
Chong Kyu Woo, Eun Kyung Choi, Hae Ryung Chung, Dong Heuk Keum
Clin Exp Pediatr. 1987;30(9):1034-1039.   Published online September 30, 1987
We experienced a case of autoimmune hemolytic anemia in 3-year-old male patient associated with acute viral hepatitis B. Characteristic findings of this disease are pallor, fever, tachycardia, jaundice, hemoglobinuria, of which the onset is acute or chronic. Although the pathogenic mechanism of this disease is uncertain, it can be associated with pneumonia, measles, varicella, viral hepatitis (50%) and underlying autoinunune deficiency (32%). Diagnosis...
Original Article
Syndrome of Inappropriate Secretion of Antidiuretic Hormone(SIADH) in Acute Respiratory Diseases.
Young Jee KIm, Young Yull Koh, Jeong Kee Seo, Hung Ko Moon
Clin Exp Pediatr. 1987;30(9):1021-1028.   Published online September 30, 1987
The SIADH incidence and relevant factors in acute respiratory diseases were evaluated in 461 children with over 28 days old, hospitalized for bronchiolitis, viral pneumonia, bacterial pneumonia, mycoplasma pneumonia and asthma, without other causes of electrolyte imbalance. The overall incidence of SIADH in acute respiratory diseases was 11.93%. The incidence in mycoplasma pneumonia (19.05%) was highest and incidence in bacterial pneumonia (17.42%), viral pneumonia (9.17%),...
Clinical Value of Urinary β₂ -Microglobulin in Patients with Urianry Tract Infection.
Nak Uk Sung, Chang Ryul Kim, Jeh Hoon Shin, Woo Gill Lee
Clin Exp Pediatr. 1987;30(9):1014-1020.   Published online September 30, 1987
Urinary tract infection (UTI) in children is relatively common infectious disease and it may be the forerunner of severe renal diseases in adulthood. The site of infection is an important factor in the evaluation of the clinical course, treatment and prognosis of patients with UTI, because patients with bacteriuria of renal origin (pyelonephritis) are probably at risk of developing the renal parenchymal reduction seen...
Diagnosis and Hydrostatic Reduction of 5 Cases of Intussusception Under Ultrasound Guidance.
Hee Kyung Park, Moon Hae Bang, Jae Ock Park, Sang Jhoo Lee
Clin Exp Pediatr. 1987;30(8):901-906.   Published online August 31, 1987
I nt ussuscept i on is the condition of invagination of one part of intestinal loop into the contiguous distal segment. During infancy and early childhood, intussusception is the most common cause of acquired intestinal obstruction, and it requires emergency treatment. Recently, the use of ultrasound as a diagnostic and therapeutic tool of intussusception is now becoming a well-established method because it is simple,...
Upper Gastrointestinal Fiberoptic Endoscopy in Children.
Dong Hyup Lee, Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Young Il Min
Clin Exp Pediatr. 1987;30(8):868-873.   Published online August 31, 1987
We observed 63 cases ranging in age from 3 years to 15 years seen by gastrofibroscopy in Dept, of Int. Med. and Dept, of Ped. of Kyung hee Univ. Hospital from January 1980 to December 1985 and following results were obtained 1) The male to female ratio was about 1:1.17. The frequency of the age distribution was 1.6% below 5 years, 25.4% in 6-10 years...
Case Report
A Case of Williams Elfin Facies Syndrome.
Kyung Jin Shin, Heon Seob Song, Byung Sook Park, In Soo Choi, Chan Uhng Joo, Jung Ku Jo
Clin Exp Pediatr. 1987;30(6):684-690.   Published online June 30, 1987
Williams elfin facies syndrome is a disorder which has previously designated as the pecular facies, mental retardation and supravalvular aortic stenosis. Supravalvular aortic stenosis is the least form of left ventricular outflow obstruction, originating at superior margin of sinuses of Valsalva just above the level of the coronary arteries. We had experienced a case of Williams elfin facies syndrome who had characteristic face, mental retardation...
Original Article
Idiopathic Thrombocytopenic Purpura in Children.
Kyu Chul Choi, Sang Ho Park, Yong Mook Choi
Clin Exp Pediatr. 1987;30(6):664-670.   Published online June 30, 1987
Forty four children with idiopathic thrombocytopenic purpura (ITP) were analyzed retrospectively and the following prognostic factors were obtained in response to treatments and clinical courses. And 73.5% of all cases were recovered within 6 months after onset (acute ITP). The patients who were admitted within 1st or 2nd week after onset showed more favorable prognosis with significance (p<0.05 and p< 0.005, respectively). The patients...
Clinico-Hematologic Observation of Neonatal Hemolytic Disease due to Minor Blood Group Isoimmunization.
Chong Woo Bae, Yong Mook Choi, Chang Il Ahn, Hyun sok Chi
Clin Exp Pediatr. 1987;30(5):504-510.   Published online May 31, 1987
The isoimmune hemolytic diseases of the newborn due to minor blood group are characterized by the abnormal titer of minor group antibody in mother’s serum and neonatal progressive jaundice caused by isoimmune hemolytic anemia. This report present the clinico-hematologic features of six cases of hemolytic diseases of newborn due to minor blood group isoimmunization who were admitted to the Kyung Hee university Hospital and presented...
A Case of Congenital Anterior Urethral Diverticulum.
Young Ho Lee, Gyu Jeon Song, Woo Yeong Chung, Moo Young Oh, Soon Yong Lee
Clin Exp Pediatr. 1987;30(4):431-434.   Published online April 30, 1987
Recently, we experienced a case of congenital anterior urethral diverticulum in 8-month-old male infant. He had recurrent fever and urinary dribbling for 3 months. The diagnosis was based on radiologic and cystoscopic findings, and anterior urethral diverticulectomy was performed. A review of literatures was also presented briefly.
Statistical Observations for Pediatric Inpatients.
Byung Cheol Han, Hack Ki Kim, Byung Churl Lee, Kyong Su Lee, Sung Hoon Cho, Du Bong Lee
Clin Exp Pediatr. 1987;30(4):385-392.   Published online April 30, 1987
We observed the patients admitted to the department of pediatrics of St. Mary*s Hospital, Catholic Medical College during the past 20 years from Jan. 1966 to Dec. 1985 and classified them by year and disease according to the International Classification of Disease by W.H.O. (1965 Revision). The results were as follows: 1) The total number of pediatric inpatients during 20 years was 18,686, of which...
A Prospective Study ot Neonatal Acute Renal Failure: The Significance of Various Diagnostic Indices.
Kyung Hyo Kim, Seung Joo Lee, Keun Lee
Clin Exp Pediatr. 1987;30(4):378-384.   Published online April 30, 1987
Acute renal failure is defined as a sudden decrease in renal function resulting in progressive retention of nitrogenous waste products. Acute renal failure should be suspected in any infant who has a sustained decrease in urine output to less than 1 ml per kg per hour, a blood urea nitrogen level above 20 mg per dl, a serum creatinine level greater than 1.0...
Chlorambucil Treatment in Chidren with Frequently Relapsing Minimal Lesion Nephrotic Syndrome.
Myung Hee Chung, Hae Woon Chang, Haeng Mi Kim, Ja Hoo Koo
Clin Exp Pediatr. 1987;30(4):370-377.   Published online April 30, 1987
A clinical study was conducted on children with frequently relapsing nephrotic syndrome to see the therapeutic effectiveness of chlorambucil therapy. Study population consisted of 21 children with biopsy-proven minimal lesion nephrotic syndrome, in whom chlorambucil therapy was given to control their frequent relapses and/or steroid dependency. Eleven patients were frequent relapser and 10 were steroid dependant. Study period extended from December 1980 to August...
Clinical Study on the Hypoplastic Right Heart Syndrome.
Sejung Sohn, Soon Ung Kang, Chung Il Noh, Jung Yun Choi, Yong Soo Yun, Chang Yee Hong, Dug Ha Kim, Jong Lin Rhi
Clin Exp Pediatr. 1987;30(3):281-290.   Published online March 31, 1987
A clinical observation was made on 12 cases of the hypoplastic right heart syndrome who were admitted to the department of Pediatrics, Seoul National University Hospital from January 1978 to May 1986. The -results were as follows; 1) The ratio of female to male was 1:1 and, according to the anatomic classification by Khoury, 6 cases were in type 1, 4 cases in type II...
The Evaluation for the Immunotherapy to Bronchial Asthmatics.
Jung Woo Shin
Clin Exp Pediatr. 1987;30(3):247-252.   Published online March 31, 1987
The changes of skin-test reactivities, total and specific serum IgE levels, and peripheral eosinophil counts were observed periodically in 20 bronchial asthmatics. The immunotherapy was performed with the Specific desensitization Vaccine(Bencard), i. e. mixture of multiple allergens specific for each patients, and scheduled reach the maintenance doses within 6 months. The skin-test reactivity index, i. e. the ratio of the average diameter of the wheal...
A Retrospective Study on the Effect of Cyclophosphamide in Children with Minmal Change Nephrotic Syndrome.
Il Soo Ha, Kwang Wook Ko, Yong Il Kim
Clin Exp Pediatr. 1987;30(2):158-174.   Published online February 28, 1987
Thirty one children associated with biopsy-proven minimal change nephrotic syndrome with frequent relapse, were placed on cyclophosphamide, and its effect was analyzed. Cyclophosphamide was given with the dosage of 2.46±0.42 mg/kg/day for 58±7 days along with the alternate day corticosteroid. Sixty three percent of the patients showed complete remission and twenty seven percent of the patients resulted in partial remission after the treatment. Those...
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