Clinical Observation and Study for Cerebrospinal Fluid Protein Levels in Aseptic Meningitis. |
D H Chee, M I Lee, S H Kim, K C Sohn |
Department of Pediatrics, National Medical Center, Seoul, Korea |
무균성 뇌막염의 임상 및 척수액 단백량에 대한 고찰 |
지동현, 이명익, 김순화, 손근찬 |
국립의료원 소아과 |
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Abstract |
Observation for clinical findings and laboratory findings, especially for cerebrosipinal fluid protein
level has been done in 57 cases of aseptic meningitis who had been admitted to pediatric dept, of
National Medical Center from Jan. ’81 to May ’85.
The results were as follows;
1) The ratio of male to female was 1.7:1, and the cases were distributed relatively evenly through
all pediatric age.
2) The monthly distribution showed peak incidence in summertime.
3) Vomiting (66.7%), headache (52.6%) and fever (49.1%) were chiefly complained and definite neck
stiffness was observed in 47% of cases
4) Leukocytosis and elevation of erythrocyte sedimentation rate in peripheral blood were not so marked.
5) On cerebrospinal fluid examination, WBC counts were less than 500/mm3 in 91% of cases and
glucose concentrations were more than 40 mg/dl in 94.2% and protein concentrations were less than
60 mg/dl in 52% of cases. Significant correlations was noted between CSF WBC counts and protein levels.
6) In acute phase of aseptic meningitis, the mean of CSF protein level was 62.36±35.81 mg/dl, and
it showed significant difference as compared with that of control group (39.95 ±51.17 mg/dl). In
convalescent phase of aseptic meningitis, the mean of CSF protein level was 39.40 ±25.24 mg/dl with
singificant decrease from that of acute phase.
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Key Words:
Aseptic meningitis, CSF protein level
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