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Original Article
A Case of Esophageal Variceal Bleeding in a Child Secondary to Portal Hypertension Associated with Cavernous Transformation of the Portal Vein Suggesting Extrahepatic Portal Obstruction.
Sun Yang Hong, Tae Won Oh, Jeong Kook Lee, Hahng Lee, Keun Soo Lee, Seok Chol Jeon, Heung Suk Seo
Clin Exp Pediatr. 1990;33(10):1406-1412.   Published online October 31, 1990
Esophageal variceal bleeding is a rare manifestation in childhood and it usually occurs secondary to portal hypertension. We experienced a case of esophageal variceal bleeding secondary to portal hypertension associated with portal obstruction but with no evidence of liver cirrhosis in a 4-year- and-10-month-old boy who was hospitalized due to hematemesis. He was a product of fullterm normal spontaneous delivery at home unattended by...
A Case of Hypertrophic Cardiomyopathy in Identical Twin.
Wea Kyoung Shin, Hae Young Lee, Hwang Min Kim, Jae Seung Yang, Baek Keun Lim, Jone Soo Kim
Clin Exp Pediatr. 1990;33(10):1399-1405.   Published online October 31, 1990
Hypertrophic cardiomyopathy is a common genetically transmitted disorder characterized by asymmetric septal hypertrophy and systolic anterior motion of the mitral valve. We have recently experienced identical twin with the hypertrophic cardiomyopathy confirmed by M-mode and 2-D echocardiography. It is the first report of hypertrophic cardiomyopathy in identical twin in Korea. So presented this case with a review of referential literatures.
Clinical Characteristics and Prognosis of Fulminant Hepatic Failure in Infants and Children.
Keum Cheon Kim, Ki Sup Chung
Clin Exp Pediatr. 1990;33(10):1362-1373.   Published online October 31, 1990
29 patients admitted into Department of Pediatrics, Severance Hospital, Yonsei University, college of medicine during 16 years period from 1974 to 1989 with the diagnosis of fulminant hepatic failure were divided into 2 groups, live and expired groups. These patients were compared with sex, age distribution and etiology and in order to find the factors responsible for death platelet counts, prothrombin time, SGOT, SGPT,...
A Case of Autoimmune Hemolytic Anemia Associated with Chronic Hepatitis in Children.
Kwan Mo Choi, Kyeong Hun Cha, Eun Yeong Kwak, Kyung Rae Moon, Yeong Bong Park
Clin Exp Pediatr. 1990;33(9):1288-1293.   Published online September 30, 1990
Recently, We experienced a case of autoimmune hemolytic anemia in a 13 year old female patient associated with chronic hepatitis. This female child manifested severe pallor, jaundice, abdominal pain and fever. This diagnosis was made on the bases of typical clinical features, C.B.C., blood chemistry, coombs test, warm antibody, immunoelectrophoresis, peripheral blood smear and bone marrow examination. The patient improved with steroid therapy. We report this...
IgA Nephropathy in Childhood.
Yong Choi, Dong Woo Son, Ja Wook Koo, Dong Kyu Jin, Hae Il Cheong, Kwang Wook Ko, Hyun Soon Lee, Yong Il Kim
Clin Exp Pediatr. 1990;33(9):1237-1243.   Published online September 30, 1990
In this study we compared between the patients with recurrent gross hematuria (group 1, n=45) and * with nephrotic range proteinuria (group 2, n=21) in IgA nephropathy who were admitted to Seoul National University Children’s Hospital during the period from January, 1980 to December, 1989. The results of the study were as follows. 1) Age of onset and sex ratio were not different between the...
Relationship between anaphylactoid purpura and Beta-Hemolytic Streptococcal Infection.
Ji Eun Lee, Young Sook Kang, Joon Sik Kim, Sung Ho Kim, Chin Moo Kang
Clin Exp Pediatr. 1990;33(9):1231-1236.   Published online September 30, 1990
Relationship between anaphylactoid purpura and beta-hemolytic streptococcal infection was obser- ved and analyzed through clinical manifestation and labortory findings in 146 cases of allergic purpura, hospitalized at Dongsan hospital, Keimyung University during the period from January, 1981 to May, 1987. The following results were obtained. 1) The age distribution of anaphylactoid purpura showed a peak incidence between 2 to 7 years of age and male preponderance was...
A Case of Adrenal Cortical Carcinoma.
Ho Won Kang, Hong Ja Kang, Hong Bae Kim, Ji Sub Oh
Clin Exp Pediatr. 1990;33(8):1159-1165.   Published online August 31, 1990
This is a case report of adrenal cortical carcinoma in a 2 year 7 month old male patient who was diagnosed by clinical features, endocrinologic studies, radiologic studies and pathologic examina- tions. Cushing syndrome and virilization caused by adrenal cortical carcinoma were found. Left total adrenalectomy was performed. No evidence of metastasis was found at the time of operation. 3 months later, lung metastases...
A Case of Hemolytic Uremic Syndrome.
Seung Cheol Lee, Chong Guk Lee, Seong Hwan Kim, Sang Woo Kim, Hyun Soon Lee
Clin Exp Pediatr. 1990;33(8):1140-1147.   Published online August 31, 1990
A female child aged 7 months was admitted because of high fever, vomiting and stuporous conciousness and revealed to have hemolytic uremic syndrome. Anuria persisted 13 days and required peritoneal dialysis 4 times a day during the anuric period. Her kidney function recovered somewhat after dialysis but neurologic complications of marked hydrocephalus and brain atrophy remained.
A Clinical Study on the Posterior Subcapsular Cataracts in Childhood Nephrotic Syndrome.
Dong Kyu Jin, Ja Wook Koo, Hae Il Cheong, Yong Choi, Kwang Wook Ko, Jong Hoon Lee, Young Suk Yu
Clin Exp Pediatr. 1990;33(8):1097-1103.   Published online August 31, 1990
A clinical study was carried out in 73 children with nephrotic syndrome who had had regular ophthalmologic examination annually at Seoul National University Children’s Hospital from March 1976 to February 1990 with the aim of finding the relationship between the posterior subcapsular cataract (PSC) and the effect of corticosteroids. The results were summarized as follows: 1) The number of patients with PSC were 23 cases...
Total Protein, Albumin and IgG Analysis of Serum and Cerebrospinal Fluid in Control and Aseptic Meningitis.
Nak Won Choi, Myung Ja Yoon, Hae Rung Chung, Dong Hyuk Kum
Clin Exp Pediatr. 1990;33(8):1057-1064.   Published online August 31, 1990
Determination of proteins in CSF and serum demonstrates two pathological conditions of CNS, namely a blood brain barrier (B.B.B.) damage and a selective elevation of IgG due to synthesis within CSF CNS. -Q albumin ratio is a sensitiv eand adequate parameter for demonstration of B.B.B. Serum CSF . „ / s^IgGratl0\ I pep \ damage and IgG Index = I Serum ) albumin ratio is a better measurement for local production of IgG...
Statistical Observation on Neonate.
Hong Ja Kang, Nam Hyuk Joo, Soon Ok Byun, Ji Sub Oh
Clin Exp Pediatr. 1990;33(8):1037-1047.   Published online August 31, 1990
Statistical observation was performed on 11,857 cases of neonates which were seen in the nursery, Pusan, Wallace Memorial Baptist Hospital, during the past 5 years from Jul. 1983 to Jun. 1988. The results were as follows: 1) Among 11,857 neonates, the percentage distribution by birth weight was 6.1% for 2,500 gm or less, 3.7% for 4,001 gm or more and the sex ratio of male...
A Case of Cold Urticaria.
Chul Ho Lee, Sung Ik Chang, Jin Han Kang, Joon Sung Lee
Clin Exp Pediatr. 1990;33(7):1012-1017.   Published online July 31, 1990
Cold urticaria is one of the most common forms of physical urticaria characterized by pruritus, hive formation, redness, swelling, angioedema and occasionally symptoms of hypotension after cold exposure. Usually the diagnosis can be ascertained with the use of an ice cube test or an ice water immersion test, in which a wheal reaction appears oh the exposed skin in 10 〜 20 minutes....
Clinical Analysis of Children with Nephrotic Syndrome.
Ki Young Cheong, Keon Su Rhee
Clin Exp Pediatr. 1990;33(7):959-969.   Published online July 31, 1990
A clinical analysis was made on 51 cases with nephrotic syndrome who were admitted to Pediatric Department of Chung Nam National University Hospital from January 1st, 1984 to December 31st, 1988. Clinical manifestation, response to the inital continuous steroid therapy, relapsing patterns, factors affecting response to steroid therapy, pathologic findings and difference in laboratory findings between relapser and nonrelapser were evaluated. Results were as follows; 1) Among...
Diaphragmatic Movements in Neonates.
Hee Shang Youn, Han Wook Yoo, Moon Hong Do, Jung Hyun Cho
Clin Exp Pediatr. 1990;33(7):901-906.   Published online July 31, 1990
Right diaphrgmatic movement was recorded in 25 neontes when asleeping or in quietly awake state. Using 5-MHz transducer of Aloka 860 color echocardiography we measured those in the supine flat, supine head up, supine head down and prone flat positions. Results were as follows: 1) Normative data of right hemidiaphragmatic movement of 25 neonates were obtained in the positions. 2) Deaphragmatic movement of posterior third was significantly greater...
A Case of Aplastic Anemia Following hepatitis.
Gae Soon Yeo, Doo Kweon Kim, Chul Ho Kim, Soon Yong Lee
Clin Exp Pediatr. 1990;33(6):864-869.   Published online June 30, 1990
We experienced a case of aplastic anemia following hepatitis in a 4-year-old girl. Pancytopenia was developed during the convalescent period of hepatitis, and it was getting worse, while serial data of liver function test showed improvement. We tried a methylprednisolone pulse therapy, and about 7 months after treatment the CBC findings returned completely normal. She has enjoyed her healthy life during follow-up of over 2...
Transsphenoidal Meningoencephalocele in Association with Hypopituitarism ans Congenital Dysplastic Optic Disc: A Case Report.
Chang Gee Kang, Jung Wan You, Sung Chul Shin, Myung Goo Min, Duk Hi Kim, Jin Guk Kim, Oh Wong Kwon, Tae Sub Chung
Clin Exp Pediatr. 1990;33(6):842-847.   Published online June 30, 1990
Transsphenoidal meningoencephalocele is congenital defects in the sphenoid bone through which meninges and brain tissue have herniated; the defect, located in the midline of the base of the skull, was first reported by Richter in 1813. The nine cases of transsphenoidal meningoencephalocele have been reported. Patients with transsphenoidal meningoencephalocele also may have other midline craniocerebral and midfacial anomalies, including additional meningoencephalocele hypertelorism, cleft palate, and abnormalities...
Treatment of Congenital Pulmonary Arteriovenous Fistula with Therapeutic Embolization in a Child.
Byung Hee Kim, Young Soo Chun, Jin Soo Choi, Jae Sook Ma, Tai Ju Hwang, Jae Kyu Kim
Clin Exp Pediatr. 1990;33(6):835-841.   Published online June 30, 1990
Congential pulmonary arteriovenous fistula is an uncommon malformation which has an abnormal connection between the pulmonary capillary bed, in which venous blood in the pulmonary artery is shunted through the fistula into the pulmonary vein without exposure to alveolar air, enters the left heart, and results in systemic arterial unsaturation, polycythemia, cyanosis and clubbing. Death often results from cerebral abscess and rupture of the...
A Case of Congenital Cystic Adenomatoid Malformation (Type1) of the Lung.
Dong Sik Kim, Hwang Min Kim, Jae Seung Yang, Baek Keun Kim, Jong Soo Kim, Dong Hwan Shin
Clin Exp Pediatr. 1990;33(6):830-834.   Published online June 30, 1990
A rare form of congenital cystic lung disease, characterized by the presence of one or usually multiple interconnecting cyst, is called congenital cystic adenomatoid malformation of the lung. This disease almost invariably presents either in live premature or stillborn infants, and death in those infants bom alive usually occurs within a few hours of birth. Infants with congenital cystic adenomatoid malformation usually have tachypnea,...
Clinical Study of Status Epilepticus in Children.
Se Chang Hamm, Chan Young Kim
Clin Exp Pediatr. 1990;33(6):790-798.   Published online June 30, 1990
The authors analyzed the causes, clinical manifestations, courses and outcomes in 29 children with status epilepticus who were admitted at Pusan National University Hospital between January 1980 and June 1989. The results were summarized as follows: 1) In sezure disorder, the incidence of status epilepticus was 7.1%. Status epilepticus was occured throughout childhood without age prevalence and the incidence male to female ratio was 3.1:1. 2) The causes...
Statistical Analysis of Patients in Seoul National University Children's Hospital (1985~1988).
Kyung Mo Kim, Kwang Wook Ko
Clin Exp Pediatr. 1990;33(6):744-753.   Published online June 30, 1990
Statistical analysis of outpatients and inpatients from 1985 to 1988 was assessed with aims to have an overal grasp of patterns and trends of childhood diseases at Seoul National University Children, s Hospital. 1) Number of outpatient visits were totally 458,390 with annual number of visits of 144,754 and average daily number of 461, including 241 visits in Department of Pediatrics. 2) Number of patients at Eemergency...
A Case of Epidermolytic Hyperkeratosis.
M J Na, E W Park, W H Choi, K W Kim, D W Kim
Clin Exp Pediatr. 1990;33(5):721-726.   Published online May 31, 1990
Epidermolytic hyperkeratosis is a type of ichthyosis. We present a case of epidermolytic hyperker- atosis in 7 months old male infant who developed generalized erythematous hyperkeratosis & vesicles at birth. Later, the skin lesions progressed to characteristic thick, grayish dark brown scales affecting flexural & intertriginous areas. Histological examination revealed hyperkeratosis, vacuolation of Malpighian cells & markedly thickening of granular layer containing many keratohyaline granules.
A Clinical Study on Hematological Findings in Children with Cyanotic Congenital Heart Disease.
Seong Ho Kim, Heung Jae Lee, Hahng Lee
Clin Exp Pediatr. 1990;33(5):642-650.   Published online May 31, 1990
Children with cyanotic congenital heart disease (CCHD) and secondary polycythemia exhibit increased susceptibility to hemorrhage or thrombosis. The hemostatic disorder manifests itself by the occurrence of excessive hemorrhage after surgery, and by increased incidence of cerebrovascular accident of a thrombotic nature during life. To assess whether the severity of polycythemia in children with CCHD is correlated with coagula- tion abnormalities, hematologic studies with preoperative and...
A case of Endobronchial Metastatic Malignant Melanoma.
Sang Hee Kim, Young Kyoo Shin, Kwang Chul Lee, Chang Sung Son, Pyung Hwa Choe
Clin Exp Pediatr. 1990;33(4):573-578.   Published online April 30, 1990
Metastatic malignant melanoma is a rare neoplasm in child. We experienced a case of endobron- chial metastatic malignant melanoma developed in a 5 year-8month-old boy, who was admitted because of dyspnea and productive cough. Diagnosis was made by endobrochia 1 biopsy and histopathologic findings. He was treated with radiation as a palliative therapy. The result was good. Tumor size decreased and symptoms im- proved. The...
A Case of Retroperitoneal Lymphangioma.
Gyu Jin Oh, Jin Hyeon Park, Hee Jung Kwon, In Sil Lee, Kui Won Park, Je Geun Chi
Clin Exp Pediatr. 1990;33(3):422-428.   Published online March 31, 1990
Cystic lymphangioma, or cystic hygroma, is a true, benign, congenital multic-ystic tumor arising from sequestration of embryonic lymphatic tissue. Most often it occurs at birth or early in life, and it was found most commonly in the neck, but rarely in the retroperitoneum and its distribution coincides with that of the primitive lymph sac. We have experienced a case of retroperitoneal cystic lymphangioma in...
A case of congenital dyserythropoietic Anemia.
Sang Oh Na, Seong Hoon Ha, Hong Hoe Koo, Hee Young Shin, Il Soo Ha, Hyo Seop Ahn, Doek Ja Oh, Myoung Hee Park
Clin Exp Pediatr. 1990;33(3):410-415.   Published online March 31, 1990
The congenital dyserythropoietic anemia refers to a group of hereditary disorders of erythropoiesis characterized by ineffective erythropoiesis, multinuclearity of erythroblasts, and secondary hemo- chromatosis. The authors report a case of anemia in a 4 month-old girl whose bone marrow showed dyserythropoietic features. A brief review of referential literatures was made.
A Case of Chronic Relepsing Pancreatitis with Calcification in Childhood.
Yo Han Kim, Min Sik Kim, Moo Young Song, Eun Ryoung Kim, Jong Duk Lee, Soon Jai Lee
Clin Exp Pediatr. 1990;33(3):398-403.   Published online March 31, 1990
A 9-vear-old girl presented with recurrent abdominal pain. Investigations failed to show any of the demonstrable causes of pancreatitis, but she was found to have pancreatic calcifications with the help of the plain abdominal x-ray, abdominal ultrasound and abdominal C—T scan. Pancreatic calcifications are virtually pathognomonic of chronic pancreatitis. We report this case and review related literatures briefly.
A Case of Congenital Cysitic Adenomatoid Malformation of Lung.
Youe Kawn Kim, Deuk Hwan Jun, Bae Young Kim, Won Il Park, Kyung Ja Lee
Clin Exp Pediatr. 1990;33(2):225-228.   Published online February 28, 1990
Congenital cystic adenomatoid malformation is a rare variant of pulmonary cystic disease char- acterized by a mass of cysts lined by proliferating bronchial or cuboidal epithelium. The onset of symptoms, which are cyanosis, and tachypnea, usually occurs during the first week of life. We have experienced a case of congenital cystic adenomatoid malformation in a 9 month-old female. The diagnosis was mady by chest...
Immunomodulation Therapy in Children with Aplastic Anemia.
Won Suk Suh, Ki Sik Min, Woo Gun Choi, Hack Ki Kim, Kyoung Sn Lee, Soon Yong Lee
Clin Exp Pediatr. 1990;33(2):170-177.   Published online February 28, 1990
Thirty patients with aplastic anemia(fifteen severe aplastic anemia and fifteen moderate aplastic anemia) treated with antilymphocyte globulin and cyclosporin A as a kind of immunomodulation therapy were studied by analysing hematologic reseponses and complications. The results were as follows; 1) Nineteen out of thirty patients (63.3%) treated with anti lymphocyte globulin plus cyclosporin A showed responses (complete response of 33.3%, partial response of 30.0%). 2) Hematologic responses according...
A Clinical Study of Hereditary Spherocytosis.
Ki Ho Kim, Kun Soo Lee, Haeng Mi Kim, Doo Hong Ahn
Clin Exp Pediatr. 1990;33(1):81-87.   Published online January 31, 1990
The following results were obtained from eight cases of hereditary spherocytosis (HS) who were admitted at the Department of Pediatrics, Kyung-pook National University Hospital from July 1984 to January 1989. The percentage of HS among the pediatric hematology patients during the same period was 2.6%. Male amd female were one and seven respectively. The mean age at the diagnosis and at onset of symptom was...
Clinical Studies on Congenital Heart Diseases.
Hee Young Chun, Dae Churl Chung, In Kyung Sung, Kyong Su Lee, Du Bong Lee
Clin Exp Pediatr. 1990;33(1):66-74.   Published online January 31, 1990
A retrospective study of 10 years* experience with surgical treatment of congenital heart disease in the St. Mary’s Hospital from 1978 to 1987 was made. Data were analyzed on 188 children with congenital heart disease who had received corrective heart surgery under the age of 18 years. The results were as follows: 1) Out of 188 patients, ventricular septal defect(54.2% of all) was the most...
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