Clinical and Experimental Pediatrics

Original Article

Cardiology

Influence of atrial septal defect on mitral valve growth after repair of coarctation of the aorta or an interrupted aortic arch in infants

Yi-Chia Wang, Heng-Wen Chou, Chi-Hsiang Huang, Hsing-Hao Huang, Yih-Sharng Chen, En-Ting Wu, Shyh-Jye Chen, Ming-Tai Lin, Shuenn-Nan Chiu, Shu-Chien Huang

Clin Exp Pediatr. 2026;69(4):322-329. Published online January 13, 2026

Web of Science 1 Crossref 1

Question: Does atrial septal defect (ASD) physiology affect postrepair mitral valve growth in patients with coarctation of the aorta or an interrupted aortic arch?
Finding: Mitral valve growth occurred after biventricular repair but not single-ventricle palliation, particularly in patients with small valves and low ASD pressure gradients.
Meaning: The ASD pressure gradient determines mitral valve growth and should guide surgical strategies in patients with borderline hypoplastic left heart syndrome.

DOI: https://doi.org/10.3345/cep.2025.02110

Pulmonology

The changes of prevalence and etiology of pediatric pneumonia from National Emergency Department Information System in Korea, between 2007 and 2014

Eun Ju Shin, Yunsun Kim, Jin-Young Jeong, Yu Mi Jung, Mi-Hee Lee, Eun Hee Chung

Clin Exp Pediatr. 2018;61(9):291-300. Published online September 15, 2018

Crossref 14

Purpose: Understanding changes in pathogen and pneumonia prevalence among pediatric pneumonia patients is important for the prevention of infectious diseases. Methods: We retrospectively analyzed data of children younger than 18 years diagnosed with pneumonia at 117 Emergency Departments in Korea between 2007 and 2014. Results: Over the study period, 329,380 pediatric cases of pneumonia were identified. The most frequent age group was...

DOI: https://doi.org/10.3345/kjp.2017.06100

A Clinical Study of Interrupted Aortic Arch

Myoung Dong Shin, Tae Hun Kang, Hyoung Doo Lee, Si Chan Sung

Clin Exp Pediatr. 1995;38(10):1349-1355. Published online October 15, 1995

Purpose : We conducted this study to determine the clinical manifestations and prognostic factors of interrupted aortic arch(IAA). Methods : We performed retrospective clinical study with chart review in 9 infants who were diagnosed as IAA between January, 1993 and December, 1994. Results : Infants with IA were from 7 days to 92 days of age. Among them, 6 cases were type...

A Case of Interrupted Aortic Arch.

Yeong Sook Kang, Sun Hee Jung, Tae Chan Kwon, Chin Moo Kang, Seok Kil Zeon, Kwang Sook Lee, Yeong Sun Yoo

Clin Exp Pediatr. 1990;33(11):1579-1585. Published online November 30, 1990

Interrupted aortic arch is a congenital anomaly in which discontinuity is present between ascending and descending aorta, and is associated frequently with ventricular septal defect and patent ductus arteriosus. Authors experienced a case of interrupted aortic arch in a 4 year old boy associated with a ventriculalr septal defect and patent ductus arteriosus. Diagnostic confirmation was made by 2-D echocardiography, cardiac cathetrization and angiogra- phy. Direct closure...

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Truncus Arteriosus Associated with Interrupted Aortic Arch.

Chang Hyun Yang, Jae Seung Yang, Jun Hee Sul, Dong Soo Kim, Sung Kyu Lee, Dong Shik Chin

Clin Exp Pediatr. 1988;31(6):779-783. Published online June 30, 1988

We experienced a case of truncus arteriousus associated with interrupted aortic arch, ventricular septal defect and patent ductus arteriosus. A 5 month old boy had complained of rapid respiration and feeding difficulty since birth. There was no visible cyanosis or clubbing toes and nails. There was a grade 2 〜3 ejection systolic murmur with maximum intensity at the left lower sternal border. Diagnosis was...

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Case Report

A Successful Repair of Interrupted Aortic Arch.

Dong Su Kim, Du Yung Lee, Jun Hee Sul, Sung Kyu Lee, Kyu Ok Choi, Bum Koo Cho, Dong Sik Chin

Clin Exp Pediatr. 1983;26(4):386-391. Published online April 30, 1983

This is a case report of Interrupted aortic arch combined with large ventricular septaldefect and patent ductus arteriosus. This 5 years old girl, she was complained of frequent upper respiratory infections, exertional dyspnea from 6 months age. The diagnosis was confirmed by cardiac catheterization and angiocardiography. Pressure of main pulmonary artery was 80/50 (63) mmHg, and that of descending aorta was 75/45(60)mmHg (Qp...

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