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Allergy

Update on pediatric allergic rhinitis: narrative review based on guideline updates

Jung Yeon Shim

Clin Exp Pediatr. 2026;69(6):473-483. Published online May 28, 2026

Intranasal corticosteroids remain the cornerstone treatment for moderate to severe allergic rhinitis. The 2024–2025 Allergic Rhinitis and its Impact on Asthma guideline update suggests that fixed intranasal antihistamine–intranasal corticosteroid combinations may provide greater symptom control in allergic rhinitis than either agent alone. A control-based patient-centered approach that incorporates real-world evidence is essential for optimizing treatment outcomes in children.

DOI: https://doi.org/10.3345/cep.2026.00444

Evidence for adverse effect of perinatal glucocorticoid use on the developing brain

Young Pyo Chang

Clin Exp Pediatr. 2014;57(3):101-109. Published online March 31, 2014

Crossref 22

The use of glucocorticoids (GCs) in the perinatal period is suspected of being associated with adverse effects on long-term neurodevelopmental outcomes for preterm infants. Repeated administration of antenatal GCs to mothers at risk of preterm birth may adversely affect fetal growth and head circumference. Fetal exposure to excess GCs during critical periods of brain development may profoundly modify the limbic...

DOI: https://doi.org/10.3345/kjp.2014.57.3.101

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