Clinical and Experimental Pediatrics

Review Article

Gastroenterology

Ingestion of foreign bodies and caustic substances in children: a narrative review on clinical evaluation and management update

Maria Rogalidou

Clin Exp Pediatr. 2026;69(1):11-21. Published online December 10, 2025

Foreign body and caustic substance ingestion in children aged 1–5 years can feature to severe and, sometimes life-threatening complications. High-risk items include batteries, magnets, and corrosive chemicals. Severity depends on object type, location, and ingestion timing. Prompt diagnosis and early endoscopic intervention are crucial. Individualized management, high clinical suspicion, and parental education are essential to improving outcomes and preventing immediate and long-term complications affecting a child’s quality of life.

DOI: https://doi.org/10.3345/cep.2025.01823

Upper gastrointestinal tract involvement of Crohn disease: clinical implications in children and adolescents

Eun Sil Kim, Mi Jin Kim

Clin Exp Pediatr. 2022;65(1):21-28. Published online September 10, 2021

Web of Science 8 Crossref 11

· Clinical manifestations of upper gastrointestinal (UGI) tract involvement in Crohn's disease (CD) are common but often clinically underestimated.
· Diagnosing CD by confirming inflammation of the UGI tract histologically is challenging because macroscopic and microscopic findings overlap with those of other diseases.
· Ongoing efforts are needed to enable a standardized assessment of UGI CD in the future.

DOI: https://doi.org/10.3345/cep.2021.00661

Original Article

Therapeutic Effect of Helicobacter pylori Eradication in Children with Recurrent Abdominal Pain Associated with H. pylori

Ji Hyun Uhm, Ki Sup Chung

Clin Exp Pediatr. 2004;47(5):547-554. Published online May 15, 2004

Purpose : In order to clarify the role of Helicobacter pylori(H. pylori) in recurrent abdominal pain, we investigated prospectively the effect of eradication of H. pylori based on symptom improvement in children with recurrent abdominal pain. Methods : Children with recurrent abdominal pain were evaluated with diagnostic upper gastrointestinal endoscopy to rule out peptic ulcer disease, etc. During endoscopy, biopsies were...

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Foreign Body in the Upper Gastrointestinal Tract in Infants and Children

Sang Heui Song, Ki Sup Chung

Clin Exp Pediatr. 1993;36(1):17-24. Published online January 15, 1993

The accidental swallowing of foreign bodies by infants and children is a common problem. The proper methods of therapy must be carefully selected according to the age of the patient, the type of foreign body, the location of impaction, the duration of ingestion, and the available medical resoruces and skills. This report reviews 41 cases of ingested foreign bodies in...

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Perforation of the Gastointestinal Tract in Infancy and Childhood.

S J Lee, Y S Kim, H D Cha, T C Kwon, C M Kang

Clin Exp Pediatr. 1988;31(12):1626-1632. Published online December 31, 1988

Thirty-nine patients with perforations of the gastrointestinal tract proved by operation were presented. 35.9% of perforations were between the age of 6-10 year and 20.5% were Neonates. Male to female ratio was 2:1. The cardinal symptom of the perforation was abdominal pain in older child and abdominal distention in the neonates. Abdominal X-ray showed subphrenic free air shadow in 48.7% of the total cases. The subphrenic free...

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Case Report

A Case of Blue Rubber Bleb Nevus Syndrome.

Kwang Soo Oh, Soon Kook Choi, San Ho Kim, Bock Keun Kee, Hyung Sun Sohn, Seok Don Park

Clin Exp Pediatr. 1986;29(12):1372-1376. Published online December 31, 1986

The Blue Rubber Bleb Nevus Syndrome is defined as rarely occuring hemangioma of the skin and gastrointestinal tract, with intestinal hemorrhage. Bean in 1958 gave the name Blue Rubber Bleb Nevus (BRBN) to a variant of bluish hemangiomas of the gastrointestinal tract which causes bleeding, which had been described for the first time by Gascoyen. We experienced a case of Blue Rubber Bleb Nevus...

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