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Review Article

The management and treatment of chronic hepatitis B in Korean children

Byung-Ho Choe

Clin Exp Pediatr. 2007;50(9):823-834. Published online September 15, 2007

Interferon (IFN) alpha has been the first line therapy of chronic hepatitis B in children, but HBeAg seroconversion occurred in 26% of treated children compared to 11% of controls in multinational randomized controlled study. Recently, lamivudine was shown to be a potent inhibitor of Hepatitis B virus (HBV) reproduction both in HBeAg positive and in HBeAg negative (the pre-core mutant...

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