Clinical and Experimental Pediatrics

Original Article

Mycoplasma pneumoniae pneumonia in Korean children, from 1979 to 2006-a meta-analysis

Jin Woo Kim, Hyun Kyong Seo, Eun Gyong Yoo, Sung Jin Park, So Hwa Yoon, Hye Young Jung, Manyong Han

Clin Exp Pediatr. 2009;52(3):315-323. Published online March 15, 2009

Purpose : This study aimed to perform a systematic review of the reports on Mycoplasma pneumoniae pneumonia in the last 30 years (1980-2006) to investigate the intervals between outbreaks, change in the peak incidence age, and diagnostic methods. We also aimed to validate the proper diagnostic criteria for M. pneumoniae pneumonia. Methods : We reviewed 62 original articles on M. pneumoniae...

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Review Article

The management of sinusitis in children

Manyong Han

Clin Exp Pediatr. 2007;50(4):328-334. Published online April 15, 2007

Sinusitis is a common medical problem in children. The prevalence of penicillin-resistant S. pneumoniae infection has been increased during the last decade. The medical management is based on the choice of antimicrobial agents. This article reviews current literatures on the management of acute bacterial sinusitis and chronic sinusitis, with an emphasis on penicillin-resistant S. pneumoniae infection. This article also explores...

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Medical Lecture Course

Helper T Cell Polarizing Through Dendritic Cells

Manyong Han

Clin Exp Pediatr. 2005;48(1):6-12. Published online January 15, 2005

In the last few years, a spectrum of dendritic cells(DCs), including toll like receptors(TLRs), might play a critical role in regulating allergy and asthma. DC plays a central role in initiating immune responses, linking innate and adaptive responses to pathogen. Human peripheral blood has three non- overlapping dendritic subset that expressed various 11 TLRs. These dendritic subsets and TLR contribute...

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