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The Variability of Growth Hormone(GH) Response to Growth Hormone-Releasing Hormone(GHRH) according to the intrinsic Growth Hormone Secretory Rhythm in Children with Normal Growth Hormone Reserve
Sei Won Yang, Hyung Ro Moon
Clin Exp Pediatr. 1993;36(3):312-319.   Published online March 15, 1993
The diagnostic value of GHRH in assenssing GH secretion in biochemical GH suficient short children was examined. GHRH(1㎍/kg i.v bolus) was given to three groups (upslope, trough, downslope) arbitrarily classified according to the basal pulsatile GH secretory pattern before GHRH administration. Cmax following GHRH administration were variable and overlapping. Two children in downslope group, three children in though group, and one...
Urinary Vitamin C Loading Test and Therapeutic Effect of Vitamin C in Children with Idiopathic Recurrent Epistaxis
In Soon Park, Woo Yeong Chung, Soon Yong Lee
Clin Exp Pediatr. 1993;36(2):266-272.   Published online February 15, 1993
Recurrent epistaxis is not one of rare symptoms in children, the well-known causes of which are anatomical abnormalities of nasal cavity and systemic bleeding tendency. But, in the majority of cases of recurrent epistasix, it is usually very difficult to find out their underlying causes, so that the treatment is only symptomatic control of nasal bleeding whenever epistaxis occurs, but...
Surfactant Replacement Therapy in Neonates with Respiratory Distress Syndrome: A Collective Evaluation of Trials from 16 Hospitals
CW Bae, YD Kwon, SJ Ko, KS Kim, HM Kim, WS Park, SH Byun, CS Son, HS Ahn, SG Lee, YP Chang, YJ Chung, KS Cho, KH Cho, KC Choeh, MJ Chey, JH Choi, JK Yoon, CI Ahn, S Chida, T Fujiwara
Clin Exp Pediatr. 1993;36(2):244-265.   Published online February 15, 1993
Surfactant replacement therapy in neonates with respiratory distress syndrome (RDS) has been introduced in our country since May 1990. The purpose of this study was to assess the effect and short-term outcome of surfactant replacement for neonatal RDS using collective data of uncontrolled trials from different hospitals in Korea. For the period May 1990 to Dec. 1991, a total of 68...
The Secular Trend of Menarcheal Age in Korea
Chang-Ho Hong, Hyung Rae Cho, Kye Suk Park
Clin Exp Pediatr. 1993;36(2):239-243.   Published online February 15, 1993
The age of puberty represents a very critical time in the life history of every young woman. The menarche stands as primary indicator of the onset of sexual maturation in females. According to 13.5 years of age in 1980s. This findings show a pronounced secular trend to earlier maturation. The purpose of this study is to determine (1)the average age at...
Systolic Pressure Amplification of the Aortic Pressure in Children with Congenital Heart Disease
Chan Uhng Joo, Byoung Geun Lee, Sun Jun Kim, Jung Soo Kim
Clin Exp Pediatr. 1993;36(2):232-238.   Published online February 15, 1993
Direct intraarterial measurement of blood pressure is an important diagnostic procedure in critical patients and premature baby care. Direct measurement was more accepted and confident method in physician than the indirect methods. But the presence of a significant amplification of systolic pressure in peripheral artery may lead to important error. So we have investigated the degree of the systolic pressure...
Childhood Infection-associated Hypocalcemia
Mi Reong Kim, Seoung Hwan Kim, Hee-Shang Youn, Chong-Hwa Kim
Clin Exp Pediatr. 1993;36(2):223-231.   Published online February 15, 1993
The causes of hypocalcemia in patients suffering from severe infection including sepsis are largely uncertain. So we measured serum albumin, total protein, cholesterol, PTH, and calcitonin of the infection-associated hypocalcemic chlidren and compared with those of normocalcemic children department of pediatrics of Gyeongsang National University Hospital. Hypocalcemic patients were compared to the decreased amount of serum albumin in the hypocalcemic...
Serial Doppler Echocardiographic Evaluation of Anthracycline Induced Left Ventricular Dysfunction in Children
Nam Geun Heo, Myung Chul Hyun, Kun Soo Lee, Sang Bum Lee
Clin Exp Pediatr. 1993;36(2):214-222.   Published online February 15, 1993
Anthracycline drugs are chemoterapeutic agents highly effective against a wide range of neoplasms. However, its administration may be complicated by cardiotoxic reactions. There is a continuum of increasing risk with increasing total dose of drug rather than an absolute cutoff point for total dose drug of that should not be exceeded under any circumstances. At the present time it appears that a...
Percutaneous Transluminal Angioplasty in Takayasu's Arteritis
Yong Soo Yun
Clin Exp Pediatr. 1993;36(2):208-213.   Published online February 15, 1993
1)Among the 24 involved vessels, 5 renal arteries and one left suclavian artery were occulded totally and they were not candidate for angioplasty. 2)Four brachiocepholic branches, three renal artery, and two abdominal aorta were short segmental narrowing in nature and they were feasible for balloon dilatation, 3)Eight sites of thoracic or abdominal aorta in 5 patients were involved in diffuse long segment...
A Study on the Relationship between Juvenile Delinquency and Family Environment
Duk Jin Yun, Jung Kyoo Park, Jong Bok Chung, Jung Mo Nam, Jong Yun Park
Clin Exp Pediatr. 1993;36(2):195-207.   Published online February 15, 1993
This study was conducted to find out an appropriate means for preventing the juvenile delinquecy(JD), which is supposed to be greatly realted to family environment. The data were collected through a questionnaire survey with a means of writing by themself, to 257 middle and high school students and 309 juvenile delinquetns who were in confinement. The question-naire was consisted of 27...
The Effect of Long-Term Corticosteroid Treatment on Height Velocity in Childhood
Byung Mun Lee, Chan Yung Kim
Clin Exp Pediatr. 1993;36(2):185-194.   Published online February 15, 1993
The auther analysed 29 patients who were treated with prednisolone, including nephrotic syndrome(13 cases). Acute leukemia (10 cases), bronchial asthma(2 cases), juvenile rheumatoid arthritis(2 cases) and ulcerative colitis(1 cases) patients in childhood, after remission induction, prolonged alternate or interrupted treatment was used. The auther observed patterns of height velocity of these patients from 1.6 to 10.3 years. The results were as...
A Study on the Atlantoaxial Instability in Children with Down syndrome
Sa Young Kim, Chan Yung Kim
Clin Exp Pediatr. 1993;36(2):179-184.   Published online February 15, 1993
To evaluate the atlantoaxial instability in children with Down syndrome, the authors analyzed the 97 children with Down syndrome attending to 2 schools for handicaped children in Pusan. The results of study were as follows; 1) The incidence of atlantoaxial instability in 97 individuals with Down syndrome was 8(8.3%) in neutral position and in 10(10.3%) in flexion, respectively. 2) The mean atlantoaxial gap...
Analysis of Foreign Body in the Children's Airway and Follow-up Study
Jae Hong Park, Chan Yung Kim
Clin Exp Pediatr. 1993;36(2):169-178.   Published online February 15, 1993
The autor analysed foreign body in the airway, divided into two groups vegetable foreign body group(VFBG) and non-vegetable foreign body group(N-VFBG), according to the nature, in 88 patients aged from 5 months to 15years who were diagnosed and treated under ventilating bronchos copy at Department of Pediatrics and Otolaryngology, Pusan National University Hospital from 1980 to 1990. Of the 88...
Study on the Frequency of Right Bundle Branch Block After Surgical Closure of Ventricular Septal Defect
Ho Joon Im, Jin Nyoung Park, Nam Su Kim, Jeh Hoon Shin, In Joon Seol, Soo Ji Moon
Clin Exp Pediatr. 1993;36(1):88-93.   Published online January 15, 1993
The purpose of this study is to evaluate the ventricular conduction abnormalities, especially RNNN, observed electrocardiographically after sugical closure of VSD. The present study population consists of 92 patients with VSD who were surgically corrected at the Hanyang University Hospital during 6 years period from Jan. 1985 to Dec. 1990. We reviewed their clinical records including surgical notes and EKG findings...
Statistical Analysis of the Prevalence and Trend of Obesity in Elementary School Children in Kwangju
Kyung Rae Moon, Young Bong Park
Clin Exp Pediatr. 1993;36(1):81-87.   Published online January 15, 1993
To estimate the prevalence and trend of obesity in primary school-age children, obesity survey was performed in children aged 6 to 12 years (5,226 boys and 5,048 girls) in Kwangju in 1991. Obesity was defined as overweight if more than 20 per cent above the median weight for height and age (relative weight>120%). The following results were obtained: 1) The prevalence of...
The Study of Serum Lipids in Grossly Obese Elementary School Students in Seoul
Seong Hang Choi, Kyoung Bum Kim, Se Geun Park, Ji Tae Chung, Chang Sung Son, Young Chang Tockgo
Clin Exp Pediatr. 1993;36(1):73-80.   Published online January 15, 1993
Our study surveyed 418 obese first grade elementary school children (279 male and 139 female), in seoul, and measured levels of serum total cholesterol, HDL Cholesterol, LDL cholesterol, triglyceride were measured in addition to the measurement of body weight and height. The following results were obtained. 1) Obesity index was catergorized into mild, moderate, and severe, and the percentage of mild was...
Evaluation of the Serum Erythropoietin Levels in Neonates
Soo Young Kweon, Gyoung Hee Kim
Clin Exp Pediatr. 1993;36(1):67-72.   Published online January 15, 1993
Erythropoietin is the major hormonal regulator of erythropoiesis. It is controlled by many factors induct=ing hypoxia in tissue. The serum erythropoietin levels of neonates have shown gradual decrease untill 1 month of age. Which they are reactivated in the period of pysiologic anemia. This change is exaggerated if the neonates are born prematurely, and the levels of erythropoietin respond to...
Neurosonographic Diagnosis of Periventricular-Intaventricular Hemorrhage in Low Birth Weiht Infants
Hee Seok Koh, Dong Kyun Ryu, Young Tack Jang, Oh Kyung Lee, Jin Ok Choi
Clin Exp Pediatr. 1993;36(1):57-66.   Published online January 15, 1993
Periventricular-intraventricular hemorrhage (PV-IVH) is one of the most important neurologic lesion of the low birth weight infants. Serial neurosonographic examinations were performed in 113 low birth weight infants who were admitted to the neonatal internsive care unit of Presbyterian Medical Center from November 1, 1990 to July 31, 1991. The results were summarized as follows: 1) The incidence of PV-IVH in he study...
A Clinical Study on Early Diagnosis in Neonatal Sepsis
Jong Kwang Lee, Hae Won Cheon, Jee Hee Park, Jung Hwa Lee, Joo Won Lee, Soon Kyum Kim
Clin Exp Pediatr. 1993;36(1):49-56.   Published online January 15, 1993
Neonatal sepsis is a major contributing factor for increased mortality and morbidity in the newborn and its successful outcome depends on early detection and prompt institution of an effective antimicrobial therapy. Accurate diagnosis of the neonatal septicemia, however, is quite difficult because its early signs and symptoms are rather subtle. This study was conducted in an attempt to search for useful...
Evaluation of the Development of High Risk Low Birth Weight Infants Using Bayley Developmental Test
Chul Lee, Yil Seob Lee, Hyung Rae Cho, Dong Kwan Han
Clin Exp Pediatr. 1993;36(1):38-48.   Published online January 15, 1993
Forty two high risk low birth weight infants who had been admitted in neonatal intensive care unit at Yongdong Severance Hospital from August 1987 to July 1990 and followed up in the high risk infants follow-up clinic were studied for evaluation of their development using the Bayley developmental test at the age of 9 month (corrected age). The results obtained were...
Normal Predicted Values of Pulmonary Function Test Korean School-Aged Children
Kyung Ae Yoon, Hyung Suk Lim, Young Yull Koh, Heon Kim
Clin Exp Pediatr. 1993;36(1):25-37.   Published online January 15, 1993
In recent years pulmonary function tests have had a wide application in clinical pulmonary diseases. By combining a number of different pulmonary function tests, abnormality present in a particular patient can be defined. This narrows the list of possible diagnosis and allows to determine accurately the degree of impairment and assess the response to therapy. To assess the pulmonary function in...
Foreign Body in the Upper Gastrointestinal Tract in Infants and Children
Sang Heui Song, Ki Sup Chung
Clin Exp Pediatr. 1993;36(1):17-24.   Published online January 15, 1993
The accidental swallowing of foreign bodies by infants and children is a common problem. The proper methods of therapy must be carefully selected according to the age of the patient, the type of foreign body, the location of impaction, the duration of ingestion, and the available medical resoruces and skills. This report reviews 41 cases of ingested foreign bodies in...
Acute Megakaryoblastic Leukemia in Children
Hong Hoe Koo, Sang Kyu Park, Eun Sil Dong, Hye Jung Park, Hee Young Shin, Hyo Seop Ahn
Clin Exp Pediatr. 1993;36(1):9-16.   Published online January 15, 1993
We analyzed the clinical and laboratory features of ten children with acute megakaryoblastic leukemia (M7) and compared the findings with those reported in the literature. The diagnosis was supported by ultrastructural examination of platelet peroxidase or immunophenotyping for glycoprotein Iib/IIIa. Of the ten children, five were girls and five were boys. The median age at diagnosis was 13 months. Two...
Clinical Study on Spinal Muscular Atrophies
Soo Ahn Chae, Yong Seung Hwang
Clin Exp Pediatr. 1992;35(12):1728-1736.   Published online December 15, 1992
Spinal muscular atrophies (SMA) are degenerative diseases of motor neurons that begin in fetal life and continue to be progressive in infancy and childhood. Since Werdnig's description of Type 1 SMA in 1891, numerous clinical and experimental studies have been carried out in America and Europe. Few cases were reported about these diseases in Korea but there was no systemic...
Clinical Study and Availability of Ultrasonography in Hemorrhagic Cystitis
Jin Park, Chi Hyung Park, Chong Woo Bae, Sung Ho Cha, Byoung Soo Cho, Chang Il Ahn, Young Tae Ko, Sun Wha Lee
Clin Exp Pediatr. 1992;35(12):1722-1727.   Published online December 15, 1992
Acute hemorrhagic cystitis characterized by gross hematuria and symptoms of bladder irritation occurs in children as a self-limited disease that must be differentiated from serious renal disease. We analyzed 22 cases of hemorrhagic cystitis which were managed in the Dept. of pediatrics, Kyung Hee university hospital and present the availability of bladder sonography for diagnosis of hemorrhagic cystitis and for follow-up. The...
Follow up Study of Urinary Tract Infection Associated with Vesicoureteral Reflux
Kyung Hee Kim, Young Jin Hong, Soon Wha Kim, Don Hee Ahn
Clin Exp Pediatr. 1992;35(12):1713-1721.   Published online December 15, 1992
The authors studied 25 cases with urinary tract infection associated with vesicoureteral reflux who were admitted to department of pediatrics, National Medical Center. The patients were managed medically or surgically and followed up. The results were summarized as follows; 1) There were no difference in age and sex distributions of the 25 cases with vesicoureteral reflux. 2) The degree of reflux classified by International...
A Cause of Transient Systolic Murmur in Neonates Physiologic Pulmonary Artery Stenosis
Hyun Joo Kwak, Phil Seob Sim, Kwang Chul Lee, Chang Sung Sohn, Joo Won Lee, Young Chang Tockgo
Clin Exp Pediatr. 1992;35(12):1696-1701.   Published online December 15, 1992
A transient heart murmur is frequently heard in normal newborn who has no congenital heart disease. The cause of this murmur remains unclear but was speculated as hypoplasia of the pulmonary arterial branches or unusual alignment of the main pulmonary artery with its branches. Pulsed Doppler and two-dimensional echocardiographic studies were undertaken in 19 newborn infants with a transient murmur and...
Statistical Study on the Incidence and Mortality Rate of Low Birth Weight Infant
Sun-ae Kang, Jae-Kag Choi, Yeon-Kyun Oh
Clin Exp Pediatr. 1992;35(12):1690-1695.   Published online December 15, 1992
A statistical study on the icidence and mortality rate of low birth weight infant (LBW) was done on 11,406 newborns delivered at Wonkwang University Hospital during 9 years from Jan. 1,983 to Dec. 1,991. The results were as follows, 1) The incidence of LBW was 10.2%. 2) The incidence of LBW was higher than that of other hospital delivery (p<0.005). 3) Mortality rate of...
Screening of urinary Tract Infection in High-Risk Neonates
Hyeon Joo Choi, Seung Joo Lee
Clin Exp Pediatr. 1992;35(12):1683-1679.   Published online December 15, 1992
Since the urinary tract infection (UTI) in neonates is often associated with major urologic anomalies, early diagnosis is essential. In the screening of UTI by urine bag, contamination is a commonly encountered problem. Suprapubic bladder puncture has therefore been recommended as the best method to confirm UTI. The purpose of this study is to assess the frequency and characteristics of...
Clinical Application of APR score in the Detection of Neonatal Infections; Comparison of Fullterm and Premature
Sei-Joon Ko, Sang Mi Ha, Mi Kyeung Lee, Soon Il Lee
Clin Exp Pediatr. 1992;35(12):1674-1682.   Published online December 15, 1992
We measured APR scores for the 100 newborns of having suspected systemic infection prospectively, and evaluated the clinical significance of the results of the APR scores; in fullterm babies and in premature babies. The percentage of high APR score group (≥2) was 81% in fullterm and 66% in premature babies. When the results of the APR scores were compared to the...
The Relationship Between Neonatal Hypoglycemia and Newborn Iron Status in Hypoglycemic Large-for-Gestational Age Infants
Myung Ja Yun, In Ho Song, Hye Lim Jung, Dong Hyuck Kum
Clin Exp Pediatr. 1992;35(12):1667-1673.   Published online December 15, 1992
We assessed the relationship between neonatal hypoglycemia and newborn iron status in hypoglycemic large-for-gestational age, euglycemic large for gestational age and euglycemic appropriate for gestational age infants that were admitted to the department of Pediatrics, Koryo General Hospital from July 1989 to June 1990. The results are as follows; 1) The incidence of large for gestational age infants was 3.3% (32...
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