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Original Article
Colon Perforation during Air Enema Reduction of Intussusception
Yong Kuk Kim, Hae Ra Im, Gwang Hoon Lee, Soo Jin Han, Yong Han Sun, Eell Ryoo, Kang Ho Cho, Hann Tchah, Hak Soo Lee
Clin Exp Pediatr. 2003;46(1):37-41.   Published online January 15, 2003
Purpose : Although air enema reduction has been known as a good method of diagnosis and treatment of intussusception, it could develop colon perforation. However, there have been few studies about this complication. So we analyzed the risk factors of colon perforation during air enema reduction in patients with intussusception. Methods : We reviewed the charts of 12 colon perforation patients...
A Comparative Study of Measles According to Age
Eun-Sung Eun, Sang-Lim Choi, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(1):33-36.   Published online January 15, 2003
Purpose : We evaluated clinical manifestations and laboratory findings in patients with measles according to age distribution. Methods : Retrospective analyses were performed using medical records of patients with measles admitted to The Catholic University of Korea, Daejon St. Mary's Hospital from October 2000 to May 2001. We divided the patients with measles into three age groups, i.e., those who were...
Associated-Genes and Virulence Factors of Staphylococcus aureus Isolated from Nasal Cavity of Neonates
Yung Bu Kim, Ji Young Moon, Jae Hong Park
Clin Exp Pediatr. 2003;46(1):24-32.   Published online January 15, 2003
Purpose : Nosocomial infection with Staphylococcus aureus, especially methicillin resistant S. aureus, has become a serious concern in the neonatal intensive care unit. The aim of this study is to investigate the virulence factors, and the relationship between the antibiotic resistance and the associated genes of Staphylococcus aureus isolated from nasal cavity of neonates. Methods : Fifty one isolates of S....
Total Parenteral Nutrition-associated Cholestasis in Premature Infants
Kyung Pil Park, Se Young Kim, Heng Mi Kim
Clin Exp Pediatr. 2003;46(1):17-23.   Published online January 15, 2003
Purpose : Cholestasis is a major complication in prolonged use of TPN, especially in the neonatal period, but there are few long-term reviews examining the clinical course in premature infants. Thus, in this study, we reviewed premature infants with TPN-associated cholestasis(TPNAC) to determine the incidence, clinical courses and possible risk factors. Methods : Retrospective review of 66 premature infants less than...
Nutritional Assessment and the Effectiveness of Dietary Counseling in Infants and Young Children with Iron Deficiency Anemia
Ja Kyoung Kim, Eun Young Ko, Yu Jin Lee, Yong Hun Jun, Soon Ki Kim
Clin Exp Pediatr. 2003;46(1):11-16.   Published online January 15, 2003
Purpose : Iron deficiency is still the most common nutrient deficient disorder despite the improvement in general health and nutrition. This study is designed to evaluate the dietary history of infants and young children with iron deficiency anemia(IDA) and the effects of nutritional counseling. Methods : This study was conducted on 120 children from 6 to 36 months of age with...
Blood Eosinophil and Serum Eosinophil Cationic Protein as a Marker of Bronchial Hyperresponsiveness in Children with Suspected Asthma
Yang Park, Hee Kang, Eun Kyeong Kang, Young Yull Koh
Clin Exp Pediatr. 2002;45(12):1577-1584.   Published online December 15, 2002
Purpose : Airway inflammation is considered to be a characteristic feature of asthma, and eosinophils are recognized as the most important inflammatory cells. This study aims to assess the importance of blood eosinophil count and serum eosinophil cationic protein(ECP) levels as a non- invasive marker of bronchial hyperresponsiveness(BHR) in children with suspected asthma. Methods : This study used data from 87...
Corticosteroids Add-on Therapy in the Acute Phase of Kawasaki Disease
Seon-Mi Kang, Eun-Kyung Moon, Su-Mi In, Hong-Ryang Kil
Clin Exp Pediatr. 2002;45(12):1571-1576.   Published online December 15, 2002
Purpose : Recently, clinical trials of steroid add-on therapy were reported with variable results in Kawasaki disease. We analyzed the clinical outcomes of patients at high risk of with Kawasaki disease(≥4 points of Harada score) treated by three commonly used different treatment regimens, with or without corticosteroids. Methods : Medical records of 96 children with Kawasaki disease treated with one of...
A Follow-Up Study after Discontinuation of Antiepileptic Drug Therapy in Children with Well-Controlled Epilepsy : The Factors that Influence Recurrence
Sa Jun Chung, Hye Jeon Chung, Young Mi Choi, Eu Hyun Cho
Clin Exp Pediatr. 2002;45(12):1559-1570.   Published online December 15, 2002
Purpose : There has been no exact answer to the question of when to discontinue antiepileptic drugs(AEDs) in children with well-controlled epilepsy for a long period. This study is about the risk factors of relapse after withdrawal of AEDs in seizure(Sz)-free patients to show a guideline for discontinuation of AEDs. Methods : One hundred and sixty-nine children were diagnosed as epileptic...
The Morphologic Changes of Parvalbumin- Immunoreactive Interneurons of the Dentate Gyrus in Kainate-Treated Mouse Hippocampal Slice Culture Epilepsy Model
Hee Sun Chung, Mi-Young Shin, Young-Hoon Kim, In-Goo Lee, Kyung-Tai Whang, Myung-Suk Kim
Clin Exp Pediatr. 2002;45(12):1551-1558.   Published online December 15, 2002
Purpose : Loss of hippocampal interneurons in dentate gyrus has been reported in patients with severe temporal lobe epilepsy and in animals treated with kainic acid(KA). Interneurons contain Ca2＋- binding protein parvalbumin(PV). The effects of kainic acid on parvalbumin-immunoreactive (PV-IR) interneurons in dentate gyrus were investigated in organotypic hippocampal slice cultures. Methods : Cultured hippocampal slices from postnatal day nine...
Assessment of the Relationship between Vigabatrin and Visual Field Defect in Children
Sa Jun Chung, Yong Hwan Chung, Eu Hyun Cho
Clin Exp Pediatr. 2002;45(12):1546-1550.   Published online December 15, 2002
Purpose : The authors carried out this study to determine the relationship between vigabatrin (VGB) and visual field defect.. Methods : Seventy eight patients older than 8 years who had epilepsy which had developed and been diagnosed, and were receiving add-on therapy, were the subjects of this study. If suspicious results were obtained from the initial test with the Humphrey automatic...
Incidence of Vesicoureteral Reflux in Asymptomatic Siblings of Patients with Reflux
Jong Shik Kim, Ja Wook Koo
Clin Exp Pediatr. 2002;45(12):1540-1545.   Published online December 15, 2002
Purpose : Vesicoureteral reflux(VUR) is defined as a retrograde flow of urine from the bladder into the upper urinary tract. It has been shown to predispose patients to hypertension, renal scarring, and end-stage renal failure if not recognized and treated. The observation that VUR occurs in siblings of children with reflux at a significantly higher rate than the general pediatric...
The Role of Neoadjuvant Chemotherapy for Advanced Stage Wilms Tumor
Chang Kyu Kang, Kwang Bin Moon, Keon Hee Yoo, Hong Hoe Koo, Hye Kyung Yoon, Kwan Hyun Park
Clin Exp Pediatr. 2002;45(12):1534-1539.   Published online December 15, 2002
Purpose : This study was designed to exclude radiation in advanced(stage 3, 4) Wilms tumor (WT) by increasing the chance of complete surgical removal with preceding neoadjuvant chemotherapy, thereby reducing the incidence of late effects. Methods : Between December 1998 and July 2002, we conducted neoadjuvant chemotherapy after needle aspiration biopsy on patients who had advanced WT. If needle...
Clinical Features of Isolated Noncompaction of the Ventricular Myocardium
Eun-Kyoung Moon, Hoon-Young Lee, Mea-Young Chang, Hong-Ryang Kil, Yong-Hun Chung
Clin Exp Pediatr. 2002;45(12):1528-1533.   Published online December 15, 2002
Purpose : Isolated noncompaction of the ventricular myocardium(INVM) is one of the unclassified cardiomyopathies that is characterized by numerous, excessively prominent trabeculations, and deep intertrabecular recesses. We performed this study to evaluate the clinical features of INVM in children. Methods : The medical records of 10 patients with INVM were reviewed. We analyzed the clinical manifestations, hemodynamics, pattern of inheritance,...
Clinical Analysis of Acute Respiratory Tract Infections by Influenza Virus in Children
Min Kyoung Kwon, Mi Ran Kim, Eun Young Park, Kon Hee Lee, Hae Sun Yoon, Kwang Nam Kim, Kyu Man Lee
Clin Exp Pediatr. 2002;45(12):1519-1527.   Published online December 15, 2002
Purpose : Although influenza virus is one of the most important causes of acute respiratory tract infections(ARTIs) in children, virus isolation is not popular and there are only a few clinical studies on influenza in Korea. We evaluated the epidemiologic and clinical features of ARTIs by influenza virus in children. Methods : From February 1995 to August 2001, nasopharyngeal aspirations were...
Effects of Single Fetal Death on Mother and Live Co-twin in Twin Pregnancy
So Youn Kim, Hae Yul Chung, Hee Jo Back, Ic Sun Choi, Chang Yee Cho, Young Youn Choi
Clin Exp Pediatr. 2002;45(12):1512-1518.   Published online December 15, 2002
Purpose : Twins have a higher mortality and morbidity than singletons. Co-twin with one fetal death is particularly at risk. We investigated the neonatal outcome of live co-twins when one fetus had died after the 20th gestational week, and associated risk factors. Methods : A retrospective study was performed in fifteen cases of twin pregnancy with single intrauterine fetal deaths...
Comparison of Rehospitalization during the First Year of Life in Normal and Low Birth Weight Infants Discharged from NICU
Sae Ah Min, Myung Won Jeon, Sun Hee Yu, Oh Kyung Lee
Clin Exp Pediatr. 2002;45(12):1503-1511.   Published online December 15, 2002
Purpose : Although the short- and long-term outcomes of low birth weight(LBW) neonatal intensive care unit(NICU) survivors have been extensively studied, much less information is available for normal birth weight(NBW) infants(greater than 2,500 gm) who require NICU care. Methods : We retrospectively examined the neonatal hospitalizations and one year health status of 302 NBW and 131 LBW admissions to our...
Allele Distribution and Frequency of Human Surfactant Protein-A1 in Korean Neonates
Kyung Shin Lee, Young Hee Kim, Jung Su Suk, Jung Ho Ko, Ook Joon Yoo, In Kyu Lee, Myung Ho Oh, Chong Woo Bae
Clin Exp Pediatr. 2002;45(12):1497-1502.   Published online December 15, 2002
Purpose : We evaluated allele frequencies and distribution of surfactant protein A1(SP-A1) in Korean neonates in order to estimate prevalence of RDS to find out new SP-A alleles, and to establish new steroid therapy. Methods : Genomic DNA was extracted from 100 neonates and served as a template in PCR for genotype analysis. SP-A gene-specific amplications and gene-specific allele determinations were...
A Study on Awareness and Knowledge of Obesity, Life Style, and Eating Habits According to Body Mass Index in High School Students
Mi Jung Kim, Kwang Hae Choi, Kyeong Soo Lee
Clin Exp Pediatr. 2002;45(12):1491-1496.   Published online December 15, 2002
Purpose : This study was performed to investigate the level of obesity awareness and to help to prevent and to treat obesity by examining the relationship between knowledge of obesity and life style. Methods : Of the students who were surveyed, 1514 answered seriously and were accepted as subjects for the study. The questionaire was anonymous and was filled in by...
The Prevalent Rates of Abnormal Serum Aminotransferase Levels and Total Cholesterol Levels among Adolescents with Obesity
Hyun Oh Jang, Chong Guk Lee, Yun Ju Kang
Clin Exp Pediatr. 2002;45(12):1484-1490.   Published online December 15, 2002
Purpose : The purpose of this study was to look at prevalences of abnormal serum aminotransferase levels and abnormal serum total cholesterol levels among adolescents with obesity in Seoul area. Methods : Body mass index[BMI(kg/m2)], serum aspartate aminotransferase(AST) alanine aminotransferase(ALT), and total cholesterol levels were measured in 26,876 adolescents(male : 13,287, female : 13,589) of first grade of high school in...
Clinical Characteristics in Patients with Kawasaki Disease Who Received Intravenous Gamma-globulin Retreatment
Deok-Soo Kim, Yoon-Soo Hahn, Heon-Seok Han
Clin Exp Pediatr. 2002;45(11):1411-1416.   Published online November 15, 2002
Purpose : Although the use of intravenous gamma-globulin(IVGG) in Kawasaki disease(KD) is effective in reducing clinical symptoms and coronary artery complications, 20-30% of patients have persistent or recrudescent fever and ongoing clinical symptoms. In these patients, the additional infusion of IVGG is considered. The authors studied the characteristics of patients who received IVGG retreatment, and compared them with the patients...
Recurrence Rate of Febrile Seizures by Combining Risk Factors
Su Jung Moon, Gu Ken Sun, Eun Young Kim, Kyong Hee Na, Sun Young Park, Kyoung Sim Kim, Yong Wook Kim
Clin Exp Pediatr. 2002;45(11):1403-1410.   Published online November 15, 2002
Purpose : In previous studies, various risk factors for recurrent febrile seizures have been identified. But none of these risk factors alone could sufficiently discriminate children at high or low risk for recurrent seizures. Therefore, we tried to identify patients at high risk of recurrent febrile seizures by combining risk factors. Methods : Two hundred and four children who had...
Intraarterial Catheter-directed Urokinase Infusion for Femoral Artery Thrombosis after Cardiac Catheterization in Infants and Children
Hyoung Doo Lee
Clin Exp Pediatr. 2002;45(11):1397-1402.   Published online November 15, 2002
Purpose : One of the major complication of arterial catheterization is the thrombosis of the iliac or femoral arteries. Tissue loss following femoral artery catheterization is rare. However long- term sequelae such as impaired limb growth and future impairment of vascular access, are also important in pediatric cardiac patients. But standard methods to treat thrombotic complication of arterial catheterization in...
A Clinical Study of Hypertrophic Pyloric Stenosis
Yoon Hee Kim, Myung Sup Jung, Soon Ok Byun
Clin Exp Pediatr. 2002;45(11):1389-1396.   Published online November 15, 2002
Purpose : This study was done to analyze the changes in the clinical conditions and the diagnosis of hypertrophic pyloric stenosis. Methods : We report a retrospective clinical analysis of 39 patients with hypertrophic pyloric stenosis from Jan. 1992 to Aug. 2001. The age and sex distribution, family and birth history, clinical symptoms, the ultrasonographic and the operative sizes of pyloric canals were compared. Results...
The Usefulness of MRCP in the Evaluation of Pancreaticobiliary Diseases in Children
Ji Hyun Uhm, Seung Yeon Lee, Ki Sup Chung
Clin Exp Pediatr. 2002;45(11):1381-1388.   Published online November 15, 2002
Purpose : Magnetic resonance cholangiopancreatography(MRCP) is a noninvasive method for imaging the pancreaticobiliary tree. The aim of this study was to evalute the usefulness of MRCP for the diagnosis of pancreaticobiliary diseases in children. Methods : From October 1996 to May 2001, 67 patients with obstructive jaundice and three patients with chronic recurrent pancreatitis were evaluated with abdominal ultrasonography and...
The Findings and Significances of Brain SPECT in Acute Mealses Encephalitis
Jung Chul Kim, Ju Mi Choung, So Hee Eun, Dae-Yeol Lee, Jung Soo Kim
Clin Exp Pediatr. 2002;45(11):1373-1380.   Published online November 15, 2002
Purpose : Acute measles encephalitis(ME) is characterized by an abrupt onset of fever and obtundation, frequently accompanied by seizures and multifocal neurological signs. The aim of this study was to clarify the clinical manifestation, progression and the brain SPECT patterns in patients with acute ME. Methods : This study included 11 children with acute ME admitted to Chonbuk National University Hospital. Ten patients received a...
Serological Analysis and Epidemiologic Characteristics of Group A Streptococci in Seoul(1998-2000)
Sun-Hee Choi, Yun-Ho Kim, Sung-Ho Cha, Ki-Sang Kim, Young-Hee Lee
Clin Exp Pediatr. 2002;45(11):1368-1372.   Published online November 15, 2002
Purpose : Group A streptococci have a cell wall which consists of M protein and T protein. T protein is known to be helpful in the understanding of the epidemiology of group A streptococci. To study the epidemiologic characteristics, we serotyped T protein of group A streptococci obtained from patients admitted to hospitals, or who visited OPD in five districts...
Organic Acidemias in Korea - Three Years Experience of Organic Acid Analysis -
You Kyoung Choi, Eung Seok Kim, Eun Joo Bae, Won Il Park, Kyung Ja Lee, Hong Jin Lee
Clin Exp Pediatr. 2002;45(11):1346-1358.   Published online November 15, 2002
Purpose : We have done this retrospective study to know the relative incidences and clinical manifestations of organic acidopathies in Korea. Methods : The results of quantitative organic acid analysis of 1,125 samples of 712 patients, referred from Jul. 1997 to Jun. 2000, were analyzed retrospectively according to four age groups (-2 mon, 3 mon-2 year, 3 years-12 years, over...
Prevalence and Associated Factors of Snoring in School-Aged Children
Sung Jong Cho, Eun Young Kim, Young Il Rho, Eun Suk Yang, Young Bong Park, Kyung-Rye Moon, Chul-Gab Lee
Clin Exp Pediatr. 2002;45(11):1340-1345.   Published online November 15, 2002
Purpose : We studied the prevalence of snoring and its association with diseases, obesity and environmental factors, as well as sleep disturbance arising from snoring, in school-aged children. Methods : The survey was performed by a special questionnaire on 1,707 children at elementary schools from 1 to 30 July 2001 in Gwangju City. The prevalence of snoring, associated factors, and sleep...
Survey on Counseling about Infant Nutrition Among Doctors on Practicing Pediatric Patients in Primary Medical Facilities
Eun Jung Doe, Eun Sil Lee, Son Moon Shin
Clin Exp Pediatr. 2002;45(11):1332-1339.   Published online November 15, 2002
Purpose : Through a survey undertaken among doctors practicing pediatric patients in primary medical facilities on nutrition during infancy, the present study was done to determine whether these doctors were giving appropriate advice on infant nutrition. Methods : We visited pediatric specialists(group one) and non-pediatric specialists or general practitioners(group two) who were practicing in Daegu to ask them...
Accuracy of References in Journal of the Korean Pediatric Society and Journals of the Korean Pediatric Subspecialty Societies and Citation Pattern Analysis
Gil Ho Cho, Mi Kyung Lee, Man Yong Han, Young Rae Kim, Seo Jung Kim, Kyu Hyung Lee
Clin Exp Pediatr. 2002;45(11):1325-1331.   Published online November 15, 2002
Purpose : We tried to check the accuracy of references in the Journal of the Korean Pediatric Society and Journals of the Korean Pediatric Subspecialty Societies. We also wanted to know the citation patterns of authors by analyzing the frequency of cited materials. Methods : Three journals were randomly selected from the 2000 issues of Journal of the Korean Pediatric Society...
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