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A Comparative Study of Measles According to Age

Journal of the Korean Pediatric Society 2003;46(1):33-36.
Published online January 15, 2003.
A Comparative Study of Measles According to Age
Eun-Sung Eun, Sang-Lim Choi, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Jin-Han Kang, Kyung-Tai Whang
Department of Pediatrics, College of Medicine, The Catholic University of Korea, Seoul, Korea
홍역에서 연령별 임상상 비교
은성은, 최상림, 이경일, 이형신, 홍자현, 강진한, 황경태
가톨릭대학교 의과대학 소아과학교실
Correspondence: 
Kyung-Yil Lee, Email: leekyungyil@yahoo.com
Abstract
Purpose
: We evaluated clinical manifestations and laboratory findings in patients with measles according to age distribution.
Methods
: Retrospective analyses were performed using medical records of patients with measles admitted to The Catholic University of Korea, Daejon St. Mary's Hospital from October 2000 to May 2001. We divided the patients with measles into three age groups, i.e., those who were under two years of age(159 patients), those between 9-11 years of age(39 patients), and those older than 16 years of age who were hospitalized in the department of internal medicine(young adult group; 23 patients). We compared clinical and laboratory characteristics among these three groups.
Results
: Almost all patients with measles were presented with fever, skin rash and cough. No statistical differences were present between the three groups in total fever duration, number of hospitalization days, complications determined with longer hospitalization for more than eight days, and positive values of anti-measles IgM. Patients under 2 years of age showed statistically higher levels of white bood cell and lymphocyte counts. However, neutropenia and lymphopenia were observed in all age groups compared with age-matched standard values. Campared with the other two age groups, the young adult group showed a higher mean level of liver enzymes(AST/ALT) and more patients with a level twice as high as the normal values.
Conclusion
: Clinical manifestations including complications according to age groups showed no significant differences in patients with measles. Hepatic involvement was more prevalent in the young adult group.
Key Words: Measles, Ages, Clinical manifestation


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