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Original Article
The Efficacy of Speech and Language Therapy for Children with Speech and Language Delays according to the Eiologies
June-Bum Kim, Jin-Soon Suh, Young-Hoon Kim, Seung-Yun Chung, In-Goo Lee, Kyung-Tai Whang, Byung-Churl Lee
Clin Exp Pediatr. 2005;48(9):924-928.   Published online September 15, 2005
Purpose : Treatment efficacy for children with speech and language delay has been the subject of considerable debate in recent years. We evaluated the clinical features of children with delayed speech and language and their prognoses according to their etiologies after 6 months of speech and language therapy. Methods : From January, 2000 to March, 2004, we retrospectively reviewed 56...
Causative Organisms in Children with Bacterial Meningitis(1992-2002)
Hyun-Jung Kim, JI-Won Lee, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Seung-Hoon Hahn, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(11):1085-1088.   Published online November 15, 2003
Purpose : This study was performed to assess the difference of organisms causing bacterial meningitis according to time. Methods : We analyzed retrospectively 40 medical records of bacteriologically proven meningitis from 1992 to 2002. We divided them into two groups; neonate's group(14 cases), and children's group(26 cases). The results of the neonate's group were compared with those of previously reported articles...
Clinical Significance of C-reactive Protein in Measles
Sang-Lim Choi, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(5):480-483.   Published online May 15, 2003
Purpose : We evaluated clinical manifestations and laboratory findings in patients with measles according to C-reactive protein(CRP) concentration. Methods : A retrospective analysis was performed using the medical records of patients with measles at The Catholic University of Korea, Daejeon St. Mary's Hospital from October 1999 to May 2000. We divided the patients with measles into four groups according to CRP...
Laboratory Values in Patients with Kawasaki Disease after Intravenous Immunoglobulin : Comparison of Patients with Coronary Artery Lesions to those without Coronary Artery Lesions
Min-Young Park, Kyung-Yil Lee, Ji-Whan Han, Hyung-Shin Lee, Ja-Hyun Hong, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(2):162-166.   Published online February 15, 2003
Purpose : We evaluated the effects of intravenous immunoglobulin(IVIG) on level of laboratory parameters examined serially according to the existence of coronary artery lesions in children with Kawasaki disease. Methods : Children with Kawasaki disease(n=63), treated with IVIG at a dose of 2.0 g/kg, were classified as a group with coronary artery lesions(CALs＋ group, n=9) or a group without coronary...
A Comparative Study of Measles According to Age
Eun-Sung Eun, Sang-Lim Choi, Kyung-Yil Lee, Hyung-Shin Lee, Ja-Hyun Hong, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2003;46(1):33-36.   Published online January 15, 2003
Purpose : We evaluated clinical manifestations and laboratory findings in patients with measles according to age distribution. Methods : Retrospective analyses were performed using medical records of patients with measles admitted to The Catholic University of Korea, Daejon St. Mary's Hospital from October 2000 to May 2001. We divided the patients with measles into three age groups, i.e., those who were...
The Morphologic Changes of Parvalbumin- Immunoreactive Interneurons of the Dentate Gyrus in Kainate-Treated Mouse Hippocampal Slice Culture Epilepsy Model
Hee Sun Chung, Mi-Young Shin, Young-Hoon Kim, In-Goo Lee, Kyung-Tai Whang, Myung-Suk Kim
Clin Exp Pediatr. 2002;45(12):1551-1558.   Published online December 15, 2002
Purpose : Loss of hippocampal interneurons in dentate gyrus has been reported in patients with severe temporal lobe epilepsy and in animals treated with kainic acid(KA). Interneurons contain Ca2＋- binding protein parvalbumin(PV). The effects of kainic acid on parvalbumin-immunoreactive (PV-IR) interneurons in dentate gyrus were investigated in organotypic hippocampal slice cultures. Methods : Cultured hippocampal slices from postnatal day nine...
Erratum
A Case of Duplication 9p Syndrome(Partial Trisomy 9p)
Me Gyoung Lee, Young-Nae Roh, Young-Hoon Kim, Chung Sun Baek, Me Gyoung Sin, Jin Lee, Pil-Sang Jang, Jin-Tack Kim, Kweon-Haeng Lee, Kyung-Tai Whang
Accepted January 1, 1970  
Trisomy 9p syndrome was first described by Rethore, et al in 1970 and about 150 cases have been reported. Trisomy 9p has been reported as either partial or complete. The term "duplication 9p syndrome" instead of "trisomy 9p syndrome" is used since most of the reported patients had only partial duplication rather than the whole arm duplication of 9p. Duplication...
Original Article
An Epidemiologic Study of Kawasaki Disease(1987-2000) : Incidence of Coronary Artery Complication in the Acute Stage
Kyung-Yil Lee, Min-Young Park, Ji-Whan Han, Hyung-Shin Lee, Jin Choi, Kyung-Tai Whang
Clin Exp Pediatr. 2002;45(6):783-789.   Published online June 15, 2002
Purpose : We evaluated the epidemiologic characteristics and incidence of coronary artery sequele of children with KD according to treatment. Methods : We retrospectively analyzed 506 medical records of children with KD, who were admitted at Daejeon St. Mary's Hospital from Jan. 1987 to Dec. 2000. Results : The mean annual incidence was 36.1±11.1 cases per year. There was a slightly higher...
Case Report
A Case of Hereditary Motor and Sensory Neuropathy Type III
Su Hyun Cho, Soo-Jin Kim, Young-Hoon Kim, Yun Tae Kim, Yoon-Kyung Lee, Dong-Un Kim, Seung-Hoon Han, Seung-Yun Chung, In-Goo Lee, Kyung-Tai Whang, Je Geun Chi
Clin Exp Pediatr. 2001;44(9):1057-1061.   Published online September 15, 2001
Hereditary motor and sensory neuropathy type III, which is also known as Dejerine-Sottas disease, is a severe demyelinating polyneuropathy which presents from birth or infancy, and is sometimes presented as a hypotonic or floppy infant. The disease is inherited autosomal recessively and includes clinical findings of generalized muscle weakness and atrophy, with the greatest severity in distal limb muscles, areflexia, and sensory loss. The...
A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):720-724.   Published online May 15, 2000
Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG...
Original Article
Clinical Study of Recurrent Parotitis in Children
Sam-Hwa Yim, Kye-Nam Yoon, Kyung-Yil Lee, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(5):619-624.   Published online May 15, 2000
Purpose : Recurrent parotitis is defined as a recurrent parotid inflammation, generally associated with sialectasis of the parotid gland. It can often be misdiagnosed as recurrent mumps. We studied the clinical and laboratory features of recurrent parotitis. Methods : Outpatient clinical records of 23 cases were analyzed retrospectively between April 1993 and March 1999. Follow-up after the last outpatient clinic...
A Clinical Study of Atypical Kawasaki Disease - A Rate of Coronary Artery Involvement -
Jin-Sook Kim, Young-Yoo Kim, Jong-Wan Kim, Won-Bae Lee, Jin-Han Kang, Kyung-Tai Whang
Clin Exp Pediatr. 2000;43(1):70-77.   Published online January 15, 2000
Purpose : Without a specific diagnostic method, the clinical diagnostic criteria for atypical Kawasaki disease is known as the presence of coronary artery changes in a patient who did not meet the already estabilished clinical criteria. With this criteria, we are put into dilemma because atypical Kawasaki disease should exhibit coronary artery disease. So, we demonstrated the rate of coronary artery involvement in atypical...
Case Report
A Case of Persistent Left Superior Vena Cava Detected on Fetal Echocardiography
Jin Lee, Young-Yoo Kim, Youn-Soo Lee, Jong-Chul Shin, Jong-Wan Kim, Chung-Sik Chun, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(11):1604-1609.   Published online November 15, 1999
We experienced a case of persistent left superior vena cava draining into the common atrium in a fetus of 26-year-old primigravida. Persistent left superior vena cava is derived from the left cardinal vein. This anomalous vessel usually drains into the right atrium via the coronary sinus and has no physiologic significance. Much less frequently, the left superior vena cava drains...
A Case of Guillain-Barré Syndrome Coinciding with Bronchial Asthma associated with Mycoplasma Pneumonia
Kyung-Yil Lee, Dong-Joon Lee, Ji-Whan Han, Sang-Won Ch, John-Sung Lee, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(8):1165-1169.   Published online August 15, 1999
Mycoplasma pneumoniae is the most common etiologic agent of pneumonia in school-aged children and young adults. It involves not only the respiratory system but includes extrapulmonary complications such as exanthem, hemolysis, arthritis, hepatic dysfuction, cardiac disease, and central nervous system disease. The pathogenesis of extrapulmonary involvements may be an autoimmune phenomena. Recent studies suggest that bronchial asthma can be initiated...
Original Article
Changes of Left Ventricular Diastolic Function in Normal Children
Jin-Hee Kim, Young-Yoo Kim, Won-Bae Lee, Jong-Wan Kim,, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(8):1063-1070.   Published online August 15, 1999
Purpose : Doppler echocardiography provides a noninvasive technique for the evaluation of left ventricular diastolic function. This study was performed to define the normal pattern of left ventricular diastolic filling by real-time Doppler flow mapping, and to determine how this pattern changes with aging in normal children. Methods : The changes in diastolic function in 89 normal subjects less than 15...
Case Report
A Case of Kawasaki Disease Diagnosed with the Assistance of Ophthalmologic Examination
Soo-Jung Ha, Kyung-Yil Lee, Sang-Won Cha, Dong-Joon Lee, Ji-Whan Han, Kyung-Tai Whang, Ik-Soo Kim
Clin Exp Pediatr. 1999;42(7):1014-1018.   Published online July 15, 1999
Kawasaki disease is a systemic vasculitis in which bilateral nonexudative conjunctivitis and anterior uveitis are common early findings in the course of illness. We report an eleven-year-old boy with atypical Kawasaki disease who was diagnosed with the help of an ophthalmologic examination. The patient presented with fever, epigastric pain with vomiting, erythematous rash, and severe bilateral conjunctival injection, a red...
Original Article
Changes in GFAP Immunoreactivity of Astrocytes in Rats with Reye's Syndrome Induced by Valproic Acid and the Effects of Carnitine Supplementation
Young-Yoo Kim, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(7):966-979.   Published online July 15, 1999
Purpose : This study was designed to investigate whether valproic acid(VPA) induces Reye's syndrome by analyzing blood chemistry, carnitine(CARN) concentration, and the morphologic changes of hepatocytes. The changes of GFAP immunoreactivity of astrocytes were examined in rats with Reye's syndrome induced by VPA. And the effects of CARN supplementation on Reye's syndrome were also investigated. Methods : Ten rats were assigned...
Clinical Analysis and Comparison of Kawasaki Disease between Patients Younger than One Year of Age and Those over One Year of Age
Hee-Sun Chung, Kyung-Yil Lee, Ji-Whan Han, Sang-Won Cha, Dong-Joon Lee, Kyung-Tai Whang
Clin Exp Pediatr. 1999;42(7):936-942.   Published online July 15, 1999
Purpose : To identify the risk factors for coronary sequelae in Kawasaki disease, we analyzed and compared the clinical features and laboratory findings of Kawasaki disease in patients younger than one year of age with those over one year of age. Methods : A retrospective chart review was conducted of all children with Kawasaki disease who were admitted to the...
A Clinical Observation of Kawasaki Meningitis and Viral Meningitis
Jae-Ho Hyun, Young-Hoon Kim, Ji-Whan Han, Jong-Wan Kim, Kyung-Tai Whang
Clin Exp Pediatr. 1995;38(6):794-803.   Published online June 15, 1995
Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis. Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100...