• Search
  • Advanced Search

Original article

  • HOME
  • ARTICLE CATEGORY
  • Original article
Article category
Original Article
Pain reducing effect of vapocoolant spray during injection and heelstick procedure in neonates
Eun Kyong Choi, Ji Mi Jung, Jong Beom Sin
Clin Exp Pediatr. 2008;51(5):481-486.   Published online May 15, 2008
Purpose : The aims of this study were to test the efficacy of vapocoolant spray to decrease the symptoms associated with pain in newborns undergoing heel stick and intramuscular injection and compare the pain relief effect of oral glucose. Methods : Randomized, controlled study including sixty newborns undergoing heel stick and intramuscular injection. Group 1 was heelsticked, Group 2 was intramuscular...
Early stress hyperglycemia as independent predictor of increased mortality in preterm infants
Young Sun Wee, Gae Hyun Ahn, Eun Gyong Yoo, In Sook Lim, Kyu Hyung Lee
Clin Exp Pediatr. 2008;51(5):474-480.   Published online May 15, 2008
Purpose : Stress hyperglycemia is common in critically ill adult patients. It is known as a predictor of increased mortality, and intensive insulin therapy has been shown to improve the prognosis in such patients. We have investigated the relationship between early stress hyperglycemia and clinical outcomes in preterm infants. Methods : In this study, 141 preterm infants with a gestational age...
A study of mothers knowledge of weaning of infants with iron-deficiency anemia
Sung Jin Kim, Dong Hyun Kim, Joo Hee Chang, Yong Hun Jun, Young Jin Hong, Byong Kwan Son, Soon Ki Kim
Clin Exp Pediatr. 2008;51(5):468-473.   Published online May 15, 2008
Purpose : Iron-deficiency anemia (IDA) is still one of the most common nutrient deficiency disorders, despite improvements in general health and nutrition. This study was designed to investigate the diagnostic values of hematological profiles, including the level of ferritin, and to evaluate the knowledge of mothers on weaning practices for infants and young children with IDA. Methods : This study...
Clinical review of acute seizures among children who visited the emergency room in Masan Samsung hospital from 2004 to 2006
Won Deok Lee, Jae Wook Yoo, Ju Suk Lee, Jun Hwa Lee, Kyung Lae Cho
Clin Exp Pediatr. 2008;51(4):420-425.   Published online April 15, 2008
Purpose : The purpose of this study was to evaluate acute childhood seizures, one of the most important causes of emergency room visits, to provide appropriate medical services. Methods : We reviewed the medical records of 433 (4.6%) pediatric patients with acute seizures that visited the emergency room at Masan Samsung hospital from 2004 to 2006. Results : The male to...
Use of herbal medicine in epileptic children
Jee Yeon Lee, Wook Sun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2008;51(4):415-419.   Published online April 15, 2008
Purpose : Herbal medicine is thought to be widely used by children with epilepsy, but there have been few studies. This study aimed to investigate the perceptions and the actual conditions of usage of herbal medicine by children with epilepsy. Methods : From July to August 2007, three hundred seventy eight questionnaires were completed by parents of epileptic children who visited...
The age and dose-related hyponatremia during carbamazepine and oxcarbazepine therapy in epileptic children
Kyu Ha Lee, Jun Hyuk Song, Sung Ho Cha, Sa Jun Chung
Clin Exp Pediatr. 2008;51(4):409-414.   Published online April 15, 2008
Purpose : To assess the prevalence of hyponatremia in epileptic children receiving carbamazepine or oxcarbazpine, we investigate serum sodium changes according to age, serum carbamazepine level, and daily oxcarbazepine dosage, and the prevalence of symptoms of hyponatremia. Methods : We reviewed the clinical data of the 197 children receiving carbamazepine and/or oxcarbazepine with or without antiepileptic therapy. And these were classified...
Complications of transcatheter closure of atrial septal defects using the amplatzer septal occluder
Seo Jin Jea, Hyo Jin Kwon, Gi Young Jang, Jae Young Lee, Soo Jin Kim, Chang Sung Son, Joo Won Lee
Clin Exp Pediatr. 2008;51(4):401-408.   Published online April 15, 2008
Purpose : Transcatheter closure of atrial septal defects (ASD) is currently established therapy as an alternative to surgery. But rarely, complications are reported in some studies. We report early and intermediate term complications associated with transcatheter closure of atrial septal defects using the Amplatzer septal occluder (ASO). Methods : From June 2003 to May 2006, 64 patients underwent transcatheter closure of...
A rise and fall in AST and ALT level in nonspecific reactive hepatitis
Tai Sung Kim, Tae Hyung Hur, Sun Jeong Lim, Joong Hyun Bin, Seung Hoon Hahn, So Young Kim, Hyun Hee Kim, Wonbae Lee
Clin Exp Pediatr. 2008;51(4):396-400.   Published online April 15, 2008
Purpose : The study was performed to assess the distribution of the diseases associated with nonspecific reactive hepatitis (NRH) for the past 10 years and to evaluate the change in the level of AST and ALT, and the difference by several variable factors. Methods : From January 1997 to December 2006, 646 patients had elevated liver enzymes among 22,763 patients admitted...
Efficacy and safety of electrolytes-free polyethylene glycol (PEG) 4000 for disimpaction in children with chronic functional constipation
Jeong Hee Lee, Ran Lee, Sun Hwan Bae
Clin Exp Pediatr. 2008;51(4):391-395.   Published online April 15, 2008
Purpose : This study was performed evaluate optimal dose for disimpaction, efficacy and safety of PEG 4000 in children with chronic functional constipation. Methods : Eighty six children with chronic functional constipation were enrolled in this prospective study at Konkuk university hospital March, 2003 through August, 2006. Success in disimpaction with PEG 4000 was defined as meeting at least two out...
Epidemic acute interstitial pneumonia in children occurred during the early 2006s
Chong Kun Cheon, Hyun-Seung Jin, Eun Kyeong Kang, Hyo Bin Kim, Byoung-Joo Kim, Jinho Yu, Seong Jong Park, Soo-Jong Hong, June Dong Park
Clin Exp Pediatr. 2008;51(4):383-390.   Published online April 15, 2008
Purpose : This study was aimed to analyze the clinical characteristics of patients with acute interstitial pneumonia who had presented similar clinical patterns from March to June, 2006 and to describe our experience of treatment and to identify risk factors associated with prognosis. Methods : The clinical characteristics, radiologic and histopathologic findings and response to steroids of 15 patients (non-survival...
The usefulness of skin test in evaluation of immunity to varicella
Ji-Young Kim, Hye Jeen Lee, Me Jin Kim, Young Ho Kim, Ji A Jung, Seung Yang, Il Tae Hwang, Hae Ran Lee
Clin Exp Pediatr. 2008;51(4):377-382.   Published online April 15, 2008
Purpose : The aim of this study is to assess the usefulness of skin test by an inactivated, 1/50 diluted solution of attenuated varicella vaccine in evaluating the immune status to varicella. Methods : Total 41 subjects (22 males, 19 females, aged 1-32 years) were enrolled from July to August, 2005. Past medical history including varicella infection, varicella vaccination were investigated...
Clinical characteristics of severe respiratory syncytial virus infection requiring mechanical ventilation in neonatal period and early infancy
Seung Han Shin, Jae Ri Kim, Jin-A Lee, Chang Won Choi, Ee-Kyung Kim, Eun Hwa Choi, Han-Suk Kim, Beyong Il Kim, Hoan Jong Lee, Jung-Hwan Choi
Clin Exp Pediatr. 2008;51(4):372-376.   Published online April 15, 2008
Purpose : To identify clinical characteristics of severe respiratory syncytial virus (RSV) in neonatal period and early infancy and provide information in clinical practice. Methods : Twelve neonates and young infants (<6 months) who were infected by respiratory syncytial virus and required mechanical ventilation between March 2005 and July 2007 were enrolled. Diagnosis of RSV infection was made based on the...
Effect of surfactant lavage in severe meconium aspiration syndrome
Soon Min Lee, He Min Kim, Ji Hyun Jeon, Min Soo Park, Kook In Park, Ran Namgung, Chul Lee
Clin Exp Pediatr. 2008;51(4):367-371.   Published online April 15, 2008
Purpose : The surfactant dysfunction may play an important role in meconium aspiration syndrome (MAS). We aim to evaluate the effect of surfactant lavage in the treatment of term infants with MAS. Methods : The medical records of 15 neonates with severe MAS admitted at Yongdong Severance Hospital from 2005 to 2007 were reviewed and analyzed. Seven infants with severe...
Predisposing factors to nipple confusion
Ji Hyun Kim, Og Ryeon Cha, Yu Kyung Seo, Sun Ju Lee, Sung Min Cho, Byung Chan Park
Clin Exp Pediatr. 2008;51(4):362-366.   Published online April 15, 2008
Purpose : The purpose of this study is to investigate the predisposing factors for nipple confusion by using questionnaires. Methods : From October, 2005 to October, 2006, we performed a survey on guardians of neonates who had been admitted to the nursery at Dongguk University Medical Center and were discharged 10 to 14 days before the survey. We reviewed their medical...
Utility of a forced expiratory flow of 25 to 75 percent as a predictor in children with asthma
Jung Wan Kang, Kyung Won Kim, Eun Soo Kim, Jun Young Park, Myung Hyun Sohn, Kyu-Earn Kim
Clin Exp Pediatr. 2008;51(3):323-328.   Published online March 15, 2008
Purpose : Asthma is defined as chronic inflammation of the lower small airways, and bronchial hyperreactivity (BHR) is a pathophysiologic feature of asthma. It has been proposed that although there is no direct variable capable of assessing the small airways, a forced expiratory flow of between 25 and 75 percent (FEF25-75) might be considered a more sensitive early marker of...
Phenotype-genotype correlations and the efficacy of growth hormone treatment in Korean children with Prader-Willi syndrome
Keun Wook Bae, Jung Min Ko, Han-Wook Yoo
Clin Exp Pediatr. 2008;51(3):315-322.   Published online March 15, 2008
Purpose : Prader-Willi syndrome (PWS) is a complex genetic disorder, caused by the deletion of the paternally derived 15q11-13 region or the maternal uniparental disomy of chromosome 15 (mUPD(15)). In this study, we compared phenotypic differences between those patients whose disease was caused by microdeletion and those caused by mUPD(15). In addition, a comparison of the efficacy of growth hormone...
Capsaicin induced apoptosis and the enhanced anticancer effect of anticancer drugs in cancer cells
Sun Young Kim, You Jin Lee, Eun Hye Park, Ho Keun Yi, Dae Sun Jo, Jung Soo Kim, Pyoung Han Hwang
Clin Exp Pediatr. 2008;51(3):307-314.   Published online March 15, 2008
Purpose : Capsaicin, the major pungent ingredient in red pepper, has long been used in spices and food additives. It has been recently shown to induce apoptosis in several cell lines through a not well known mechanism. The aim of this study was to investigate the apoptosis-inducing effect of capsaicin on gastric cancer cells, and to provide valuable information concerning...
Clinical characteristics and prognostic factors for survival in hemophagocytic lymphohistiocytosis
Khi Joo Kim, Ki Hwan Kim, Taek Jin Lee, Jin-Kyong Chun, Chuhl Joo Lyu, Dong Soo Kim
Clin Exp Pediatr. 2008;51(3):299-306.   Published online March 15, 2008
Purpose : Hemophagocytic lymphohistiocytosis (HLH) is a rare but fatal disorder characterized by fever, splenomegaly, pancytopenia, and hemophagocytosis in the bone marrow and other tissues. In this study, we investigated the clinical manifestations and prognostic factors in patients with HLH. Methods : We retrospectively analyzed the data from 29 patients who were diagnosed whit HLH in the Severance Children's Hospital from...
Therapeutic response of cyclosporine and outcome in steroid resistant nephrotic syndrome
Hyung Soon Choi, Joo Hoon Lee, Young Seo Park
Clin Exp Pediatr. 2008;51(3):293-298.   Published online March 15, 2008
Purpose : The aim of our study was to evaluate the therapeutic response to cyclosporine, time to remission and side effects in steroid resistant nephrotic syndrome (SRNS). Methods : This study included 22 children with idiopathic SRNS who were treated with cyclosporine between June 1989 and August 2006. Medical records were reviewed retrospectively. Results : The mean age of patients at diagnosis...
Analysis on the association between EEG and 2-deoxy-2-[18F]-D-glucose (FDG)-PET findings in children with epilepsy
Yun Jung Hur, Joon Soo Lee, Jong Doo Lee, Heung Dong Kim
Clin Exp Pediatr. 2008;51(3):286-292.   Published online March 15, 2008
Purpose : We performed EEG and PET on children with epilepsy concomitantly in order to evaluate the effects of epileptiform and non-epileptiform discharge of EEG on glucose metabolism. Methods : Seventy three children with epilepsy who had PET and EEG simultaneously were included in our study. The subjects were classified in two ways: (1) based on the frequency of epileptiform...
A study on the clinical courses, sigmoidoscopic and histologic findings of allergic proctocolitis
Joo Hee Lee, Sung Shin Kim, Jae Ock Park
Clin Exp Pediatr. 2008;51(3):276-285.   Published online March 15, 2008
Purpose : Allergic proctocolitis is a major cause of bloody stool in early infancy. This study was aimed at ascertaining the clinical courses, sigmoidoscopic and histologic findings of allergic proctocolitis. We also analyzed the relationship between peripheral eosinophilia, the age at symptom onset, and sigmoidoscopic and histologic findings. Methods : We reviewed 25 infants retrospectively who had sigmoidoscopy and biopsy...
Discrimination between obstructive sleep apnea syndrome and primary snoring in children : comparison of clinical parameters and behavioral disturbance
Hyun-Joo Seo, Jae Suk Lee, Hong-Beom Shin, Eui-Joong Kim, Hyun-Joon Shim, Young-Min Ahn
Clin Exp Pediatr. 2008;51(3):267-275.   Published online March 15, 2008
Purpose : To determine whether primary snoring could be distinguished from obstructive sleep apnea syndrome (OSAS) by clinical evaluation and symptom scores. Methods : 56 snoring and 20 asymptomatic subjects were recruited and polysomnography was used to confirm that there were 39 OSAS, 17 primary snoring, and 20 control subjects. We evaluated the size of the childrens adenoids and tonsils....
Glutathione S-transferase polymorphism of neonatal hyperbilirubinemia in Korean neonates
Chang Seok Kang, Seung Su Hong, Ji Sook Kim, Eun Ryoung Kim
Clin Exp Pediatr. 2008;51(3):262-266.   Published online March 15, 2008
Purpose : Glutathione S-transferase (GST) is a polymorphic supergene family of detoxification enzymes that are involved in the metabolism of numerous diseases. Several allelic variants of GSTs show impaired enzyme activity and are suspected to increase the susceptibility to diseases. Bilirubin is bound efficiently by GST members. The most commonly expressed gene in the liver is GSTM1, and GSTT1 is...
The relationship between leptin adiponectin ratio and insulin resistance in healthy children
Gae-Hyun Ahn, Shin-Hye Kim, Eun-Gyong Yoo
Clin Exp Pediatr. 2008;51(3):256-261.   Published online March 15, 2008
Purpose : Leptin and adiponectin are two representative adipocytokines. Leptin increases, but adiponectin decreases, with obesity and insulin resistance. We aimed to study the relationship between the leptin/adiponectin ratio and insulin resistance in healthy children. Methods : Seventy-seven healthy children (36 boys and 41 girls) were enrolled in this study. Anthropometric measurements were performed, and the percentage of weight for...
A study on the attitudes of middle school students concerning height
Won Derk Lee, Jae Wook Lieu, Jun Wha Lee, Joo Seok Lee, Kyung Lae Cho
Clin Exp Pediatr. 2008;51(3):248-255.   Published online March 15, 2008
Purpose : The purpose of this study was to evaluate the attitudes of middle-school students about height and their behaviors related to height gain. Methods : One thousand four hundred twenty two middle-school students were included. We requested that the students complete a battery of questionnaires asking about problems associated with height. Results : There was a clear difference between...
Effects of an intensive asthma education program on asthmatic children and their caregivers
Kang Jin Seo, Gun Ha Kim, Byung Keun Yu, Yun Ku Yeo, Jong Hoon Kim, Eu Ddeum Shim, Mi Ri Yoon, Young Yoo, Ji Tae Choung
Clin Exp Pediatr. 2008;51(2):188-203.   Published online February 15, 2008
Purpose : Asthma is one of the most common chronic childhood disease. Education of asthmatic children and their families about asthma and its management may improve disease control, reduce symptoms, and improve school performance. The aim of the study was to evaluate the effects of an intensive asthma education program in asthmatic children and their families on outcome measure...
Relationship between exhaled nitric oxide and pulmonary function test in children with asthma
Han-Seok Ko, Sung-Hoon Chung, Yong-Sung Choi, Sun-Hee Choi, Yeong-Ho Rha
Clin Exp Pediatr. 2008;51(2):181-187.   Published online February 15, 2008
Purpose : Asthma is characterized by reversible airway obstruction and bronchial hyperresponsiveness result from airway inflammation. Fraction of nitric oxide in expired air (FeNO) has recently been investigated as a noninvasive measure of airway inflammation. FeNO has been reported to correlate with induced sputum eosinophilia and methacholine challenge test that it is represent severity of asthma. The purpose of this...
Neuroprotective effects of geneticin (G418) via apoptosis in perinatal hypoxic-ischemic brain injury
Mi Ju, Hyun Ju Lee, Sun Ju Lee, Eo Su Seo, Hye Jin Park, Kye Yang Lee, Gyeong Hoon Lee, Eun Jin Choi, Jin Kyung Kim, Jong Won Lee, Hai Lee Chung, Woo Taek Kim
Clin Exp Pediatr. 2008;51(2):170-180.   Published online February 15, 2008
Purpose : Some antibiotics were known to exert neuroprotective effects in the animal model of hypoxic-ischemic (H-I) brain injury, but the mechanism is still unclear. A recent study reported that geneticin (G418), an aminoglycoside antibiotic, increased survival of human breast cancer cells by suppressing apoptosis. We investigated the neuroprotective effects of systemically administrated geneticin via anti-apoptosis following the H-I brain...
Efficacy and safety of oxcarbazepine in epileptic children
Hye Kyung Shin, Yoon Lee, Jee-Yeon Lee, Wooksun Choi, So-Hee Eun, Baik-Lin Eun, Young Sook Hong, Joo Won Lee
Clin Exp Pediatr. 2008;51(2):162-169.   Published online February 15, 2008
Purpose : Oxcabarzepine (OXC), newly recommended antiepileptic drug, has been prescribed for patients with partial seizures and generalized tonic clonic seizures in Korea from 1999. There are limited reports about an efficacy of OXC therapy in epileptic children in Korea. This study evaluated the efficacy and safety of OXC in the light of our experience. Methods : The patients, who had...
Outcome of typhlitis in children with cancer
Jae Min Lee, Kwang Hae Choi, Jeong Ok Hah
Clin Exp Pediatr. 2008;51(2):156-161.   Published online February 15, 2008
Purpose : Neutropenic enterocolitis is an acute, life-threatening inflammation of the small and large bowel, often seen in children with malignancies during periods of prolonged or severe neutropenia. The optimal management for typhlitis in pediatric oncology patients has been debateful between operative and nonoperative approaches. The purpose of this study was to review the outcome of medical management of patients...
TOPICS

Browse all articles >

ARTICLE CATEGORY

Browse all articles >

BROWSE ARTICLES
FOR CONTRIBUTORS
ABOUT
Editorial Office
Korean Pediatric Society
#1606 Seocho World Officetel, 19 Seoun-ro, Seocho-ku, Seoul 06732, Korea
Tel: +82-2-3473-7306    Fax: +82-2-3473-7307    E-mail: office@e-cep.org                

Clinical and Experimental Pediatrics is an open access journal. All articles are distributed under the terms of the Creative Commons Attribution NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/)

Copyright © 2026 by Korean Pediatric Society.      Developed in M2PI