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Young Suk Shim

2 Articles

Review Article

Endocrinology

Genetic factors in precocious puberty

Young Suk Shim, Hae Sang Lee, Jin Soon Hwang

Clin Exp Pediatr. 2022;65(4):172-181. Published online October 18, 2021

Web of Science 19 Crossref 25

· Mutations in the kisspeptin (KISS1), kisspeptin receptor (KISS1R), makorin ring finger protein 3 (MKRN3), and delta-like homolog 1 (DLK1) genes are associated with idiopathic central precocious puberty (ICPP).
· A few genes related to pubertal onset have been implicated in ICPP.
· Epigenetic factors such as DNA methylation, histone posttranslational modifications, and noncoding ribonucleic acids may be related to ICPP

DOI: https://doi.org/10.3345/cep.2021.00521

Editorial

Endocrinology

Pediatricians must consider familial environment when diagnosing and managing childhood obesity

Young Suk Shim

Clin Exp Pediatr. 2022;65(1):31-32. Published online April 19, 2021

•The prevalence of childhood obesity is increasing worldwide, including in the Republic of Korea, creating a major public healthissue.
•Accumulated evidence indicates a strong relationship between parentalandchildobesity.
•A family-based approach is indicated to prevent and manage childhoodandadultobesity.

DOI: https://doi.org/10.3345/cep.2021.00318

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