- Original Article
- A Study on the Serum Level of Phenytoin after Intravenous Administration of Loading Dose
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In Joon Seol, Young Iee Yu
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Clin Exp Pediatr. 1997;40(10):1435-1442. Published online October 15, 1997
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Purpose : Phenytoin is effectively and widely used drug for the treatment of status
epilepticus and patient with ongoing seizure by intravenous infusion. It is generally
recommended to maintain serum concentration above 10μg/ml for the sustained effective
anticonvulsant effect. This study was designed to know the optimal time to begin oral
maintenance therapy after initial intravenous infusion.
Methods : Total 17 patients with status epilepticus... |
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