- Original Article
- The Preventive Effect of Dexrazoxane and Pentoxifylline on Adriamycin Induced Cardiomyopathy
-
Ling Zhu, Eun-Jung Bae, Il-Soo Ha, Jung-Wook Seo, Chung-Il Noh, Jung-Yun Choi, Yong-Soo Yun
-
Clin Exp Pediatr. 2005;48(12):1378-1384. Published online December 15, 2005
-
|
|
Purpose : We hypothesized dexrazoxane(DXR) and pentoxifylline(PTX) may prevent myocardial damage in adriamycin(ADR)-induced cardiomyopathic rat model. We also investigated their effects on the myocardial apoptosis and fibrosis in ADR induced cardiomyopathy.
Methods : The six-week old female Spregue-Dawley rats were divided into control group(CNT, n= 4), ADR group(n=6), ADR＋DXR group(DXR, n=5), ADR＋PTX group(PTX, n=6), ADR＋DXR＋PTX group(DXPT, n=5). ADR(5 mg/week, twice) was... |
-
-
- Evaluation of Prognostic Factors in Corrected Transposition of the Great Arteries at Mid-term Follow-up
-
Young-Hwan Song, Hyok-Joo Kwon, Gi-Beom Kim, Soo-Jung Kang, Eun-Jung Bae, Chung-Il Noh, Yong-Soo Yun, Jeong-Ryul Lee, Yong-Jin Kim, Joon-Ryang Rho
-
Clin Exp Pediatr. 2003;46(2):154-161. Published online February 15, 2003
-
|
|
Purpose : The prognosis of patients with corrected transposition of the great arteries(C-TGA) is variably affected by associated intracardiac defects, systemic right ventricular function, tricuspid valve competence, and conduction disturbances. This study aims to evaluate the importance of those factors at mid-term follow-up.
Methods : Medical records of 94 patients(males 58, females 36; mean age at last follow-up, 12? years; mean... |
-
-
- Clinical Trends in Acute Rheumatic Fever in Korean Children : Mailed Questionnaire Survey from 1988 to 1997 (Compared with 1978-1987)
-
Hyeon-Ho Kang, Sung-Ho Cha, Kyong-Su Lee, Sang-Bum Lee, Tae-Chan Kwon, Young-Chang Tockgo, Chang-Sung Son, Jin-A Son, Hee-Ju Park, Yong-Soo Yun, Jung-Yun Choi, Chang-Hwi Kim, Chul-Ho Kim, Tai-Ju Hwang, Jae-Sook Ma, Chan-Uhng Joo, Nam-Su Kim
-
Clin Exp Pediatr. 1999;42(10):1381-1391. Published online October 15, 1999
-
|
|
Purpose : The purpose of this study was to assess the frequency of acute rheumatic fever(ARF) among children in Korea and to describe trends in its clinical characteristics compared to data from a previous study(1978-1987).
Methods : A mailed questionnaire survey sent to the pediatric departments of 13 general hospitals in Korea requested the total number of patients with ARF and... |
-
-
- Developmental Morphology of the Atrial Venous Component in the iv/iv Mouse
-
Young-Hwue Kim, Yong-Soo Yun, Jeong-Wook Seo
-
Clin Exp Pediatr. 1998;41(7):931-940. Published online July 15, 1998
-
|
|
Purpose : Developmental processes of atria in embryos or fetuses of the iv/iv mouse were studied to find the differences between right and left atrial chambers and to identify the characteristics of atrial isomerism in the abnormal laterality syndrome.
Methods : Seventy-three embryos from SI/Col iv/iv mice(Jackson's laboratory, USA) or fetuses at the 10th-13th day were used. They were examined using... |
-
-
- Studies on the diuretic activity of the serum of the patient with diabetes insipidus
-
Kook-Choo Rie, Yong-Soo Yun, Ho-Sung Lee, Jeong-Ki Seo, Dong-Hwan Lee
-
Clin Exp Pediatr. 1976;19(2):99-112. Published online February 28, 1976
-
|
|
Diabetes insipidus is the syndrome which results from abnomality in production or release of ADH. Recently there have been used two nonhormonal forms of therapy in the treatment of DI: 1)Various diuretics, primarily thiazides and 2)The oral hypoglycemic agents, the sulfonlureas. Arduino and other numerous invesgators demnstrated that sulfonylurea chlorpropamide (Diabinase) and tolbutamide(Drinase) had a ADH-Iike effect in a patient... |
-
-
|
