Clinical and Experimental Pediatrics

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Tae Hwa Kim (Kim TH)

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Case Report

Two Cases of Gitelman's Syndrome Diagnosed by Renal Clearance Study

Tae Hwa Kim, Seung Jun Kim, Yu Kyung Seo, Jung-Yeon Shim, Hye Lim Jung, Moon Soo Park, Dong Hyuk Kum

Clin Exp Pediatr. 2002;45(3):413-417. Published online March 15, 2002

Gitelman's syndrome is an autosomal recessive disorder characterized by hypokalemic metabolic alkalosis, hypomagnesemia, and hypocalciuria that has recently been reported to be linked to thiazide-sensitive Na-Cl cotransporter gene mutation. In this study, we performed renal clearance studies to differentiate Gitelman's from Bartter's syndrome and to confirm the diagnosis in two patients clinically diagnosed with Gitelman's syndrome. Each patient was hydrated...

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