- Original Article
- The Effect of Milk on the Bioavailability of 6-mercaptopurine
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Sun Kyu Park, Ran Ju Kim, Pyoung Ha Hwang, Soo Chul Cho, Jung Soo Kim
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Clin Exp Pediatr. 1994;37(12):1732-1737. Published online December 15, 1994
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The purine antimetabolite 6-Mercaptopurine (6-MP) has been in clinical use for over 30 years and is still a widely used agent in the treatment of childhood acute lymphoglastic leukemia. The bioavailibility, clinical effecacy and toxicity of 6-MP administered orally for maintenance therapy of children with acute lymphoblastic leukemia are highly variable in many studies, as well as at different times... |
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- Changes of IgG Subclasses in the Sera of the Children with Kawasaki Disease
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Seog Beom Cho, Sun Kyu Park, Pyoung Han Hwang, Jung Soo Kim, Sa Hyoung Choi
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Clin Exp Pediatr. 1993;36(9):1197-1202. Published online September 15, 1993
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Kawasaki disease is an acute vasculitis of infancy and early childhood characterized by high fever, rash, mucositis, lymphadenopathy and coronary artery damage. The failure to indentify a causative organism using convetional culture and serological techniques, and the lack of response to antibiotics indicate that the disorder is probably not due to any known bacterial or viral pathogens. During... |
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- Case Report
- Changes of Serum IgG4 in Allergic Patients
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Soo Young Cho, Sun Kyu Park, Pyoung Han Hwang, Jung Soo Kim
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Clin Exp Pediatr. 1993;36(3):403-408. Published online March 15, 1993
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This study ws performed to evaluate the changes of serum IgG4 level in children with allergic diseases. Serum IgE, IgG and IgG4 level were measured using enyzme immunoassay(IgE) and radial immunodiffusion method (IgG and IgG4) in 21 children with bronchial asthma, allergic rhinitis or urticaria.
Eosinophil counts in peripheral blood and the values fo serum IgE were significantly increased in allergic... |
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