- Original Article
- Association between polymorphisms in Interleukin-17 receptor A gene and childhood IgA nephropathy
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Seung-Ah Baek, Won-Ho Hahn, Byoung-Soo Cho, Sung-Do Kim
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Clin Exp Pediatr. 2010;53(2):215-221. Published online February 15, 2010
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Purpose : Interleukin-17 (IL-17) is produced by activated CD4+T cells and exhibits pleiotropic biological activity on various cell types. IL-17 was reported to be involved in the immunoregulatory response in IgA nephropathy (IgAN). Our aim was to investigate the association between single-nucleotide polymorphisms (SNPs) in IL-17 receptor A (IL-17RA) gene and childhood IgAN.
Methods : We analyzed the SNPs in the... |
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- Case Report
- Cerebellar cavernous hemangioma that presented with posterior neck myalgia
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Seung-Ah Baek, Kyung-Lim Yoon, Kye-Shik Shim, Jae-Seung Bang
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Clin Exp Pediatr. 2008;51(12):1363-1367. Published online December 15, 2008
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Cavernous hemangioma can occur in the entire brain but rarely in cerebellum, especially in the pediatric age group. Headache, seizure, gait disturbance, recurrent bleeding may be seen. This tumor is a relatively benign condition but if the lesion located in the posterior fossa or the brain stem bleeds, irreversible brain damage may occur because of its restrictive space. Moreover, it... |
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