- Original Article
- Neonatology (Perinatology)
- The protective effect of CXC chemokine receptor 2 antagonist on experimental bronchopulmonary dysplasia induced by postnatal systemic inflammation
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Seung Hyun Lee, Chang Won Choi
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Clin Exp Pediatr. 2021;64(1):37-43. Published online July 15, 2020
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Question: Can CXC chemokine receptor 2 (CXCR2) antagonist preserve alveolarization by attenuating the inflammation induced by systemic lipopolysaccharide (LPS) administration in a rat model of bronchopulmonary dysplasia (BPD)?
Finding: CXCR2 antagonist significantly decreased neutrophil counts in bronchoalveolar lavage fluid and peripheral blood induced by systemic LPS administration and restored alveolarization in newborn rats.
Meaning: CXCR2 antagonist protected the lungs from the inflammation in a rat model of BPD. |
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- Case Report
- Diphyllobothrium latum infection in a child with recurrent abdominal pain
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Seung Hyun Lee, Hyun Park, Seung Taek Yu
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Clin Exp Pediatr. 2015;58(11):451-453. Published online November 22, 2015
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Diphyllobothrium latum infection in humans is not common in Republic of Korea. We report a case of fish tapeworm infection in a 10-year-old boy after ingestion of raw perch about 8 months ago. The patient complained of recurrent abdominal pain and watery diarrhea. A tapeworm, 85 cm in length, without scolex and neck, was spontaneously discharged in the feces of... |
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- Original Article
- Serum procalcitonin as a diagnostic marker of neonatal sepsis
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In Ho Park, Seung Hyun Lee, Seung Taek Yu, Yeon Kyun Oh
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Clin Exp Pediatr. 2014;57(10):451-456. Published online October 31, 2014
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Purpose We evaluated serum procalcitonin (PCT) as a diagnostic marker of neonatal sepsis, and compared PCT levels with C-reactive protein (CRP) levels. MethodsWe retrospectively reviewed the medical records of 269 neonates with a suspected infection, admitted to Wonkwang University School of Medicine & Hospital between January 2011 and December 2012, for whom PCT and CRP values had been obtained. Neonates were categorized... |
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- Case Report
- Hand-Foot syndrome induced by sorafenib, a multitargeted tyrosine kinase inhibitor, in a patient with advanced renal cell carcinoma
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Seung Hyun Lee, Sung Hun Noh, Sun Young Kim, Kyu Yun Jang, Pyoung Han Hwang
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Clin Exp Pediatr. 2009;52(1):119-123. Published online January 15, 2009
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Renal cell carcinoma (RCC) arising from epithelial cells of the renal tubules is a highly aggressive and malignant tumor in all ages; however, it rarely occurs in children. the standard treatment for RCC is radical nephrectomy with lymph node dissection when the tumor is localized and can be completely resected. Adjuvant chemotherapy, radiotherapy, and immunotherapy are used for pediatric patients... |
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- Original Article
- Results of radiofrequency catheter ablation in children and
adolescent with tachyarrhythmia
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Young Beom Chang, Seung Hyun Lee, Eun Young Kang, Kyoung-Suk Rhee, Chan Uhng Joo
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Clin Exp Pediatr. 2007;50(11):1085-1090. Published online November 15, 2007
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Purpose : Radiofrequency catheter ablation (RFCA) has become an effective therapeutic modality for treating pediatric tachyarrhythmias. Using conventional RFCA catheters, ablation of parahisian accessory pathways may be difficult and have high risk for heart block. We reviewed the efficacy and complications of the RFCA in children and adolescent with arrhythmias including parahisian accessory pathways.
Methods : We studied 48 patients... |
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- Predictive value of cobalt chloride solution for hypohidrosis with topiramate
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Hyuk Lee, Seung Hyun Lee, Sun Jun Kim
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Clin Exp Pediatr. 2006;49(11):1180-1185. Published online November 15, 2006
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Purpose : The aims of this study were to verify the incidence of hypohidrosis and to determine the predictive value of noninvasive indicator test (NeurocheckTM) for sweating after administration of topiramate in newly diagnosed pediatric epileptic patients.
Methods : A total of 46 epileptic patients (22 boys; 24 girls) on topiramate treatment were evaluated in this study at the Department... |
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- A Domestic Outbreak of Bacterial Dysentery Caused by Extended-Spectrum β-Lactamase(ESBL)-producing Shigella sonnei
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Hyun Taek Lim, So Hee Lee, Jung Hwa Lee, Jeong Eun Kim, Kyo Sun Kim, Eun Ju Jeong, Seung Hyun Lee, Chang Gyu Kang, Seong Jin Hong
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Clin Exp Pediatr. 2005;48(10):1107-1115. Published online October 15, 2005
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Purpose : An outbreak of ESBL-producing Shigella sonnei enteritis was unprecedented not only in Korea but throughout the world in the past. We intended to devise a management guideline for ESBL-producing shigellosis based on analysis of clinical manifestations and response to therapy.
Methods : We analyzed 103 patients who were admitted to the hospital with acute GI symptoms and were... |
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