Clinical and Experimental Pediatrics

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Original Article

Cytokine profile of Post–cardiopulmonary bypass in children

Kantara Saelim, Kanokpan Ruangnapa, Jirayut Jarutach, Pongsanae Duangpakdee, Smonrapat Surassombatpattana, Pharsai prasertsan

Background: Open cardiac surgery involving cardiopulmonary bypass (CPB) triggers a systemic inflammatory response that significantly affects clinical outcomes. However, the dynamics and specific roles of cytokine release after CPB in the pediatric population remain unclear.
Purpose: To evaluate the dynamics of cytokine levels and their association with low cardiac output syndrome (LCOS)-related outcomes. Methods: A prospective observational cohort study was conducted of 32 children who underwent elective open cardiac surgery...

DOI: https://doi.org/10.3345/cep.2025.00836 [Accepted]

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