Clinical and Experimental Pediatrics

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Myung Hoon Lee (Lee MH)

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Case Report

Familial Adenomatous Polyposis Improved by COX-2 Inhibitor in a Child

Ki Won Oh, Se Young Kim, Hwan Suk Lee, Myung Hoon Lee, Byung Ho Choe

Clin Exp Pediatr. 2002;45(12):1591-1595. Published online December 15, 2002

Familial adenomatous polyposis(FAP) is an autosomal dominant disease characterized by numerous adenomas in the colorectum. Patients with FAP are always at risk of malignant transformation, so that colectomy is unavoidable. NSAID, such as sulindac, and selective COX-2 inhibitor, such as celecoxib, have shown a positive effect on FAP by causing polyp regression in some patients. We report a case of...

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