Clinical and Experimental Pediatrics

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Original Article

The Changes of Apoptosis and Viability in Stem Cells after Thawing with Lapse of the Time

Seun Joo Park, Sang Young Bae, Kyung Ha Ryu, Il Tae Whang, Kyung Hyo Kim, Young Mi Hong, Kyung Hee Kim, Keun Lee, Joo Young Seoh

Clin Exp Pediatr. 2000;43(12):1576-1582. Published online December 15, 2000

Purpose : Thawed stem cells should be infused as early as possible because delay of infusion leads to decrease of cell viability and formation of DNA clumping. The procedure of 10% Dimethyl sulfoxide(DMSO) removal and a long distance from the thawing location to the patient are the main causes of delay of infusion that results in the loss of cell...

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