- Review Article
- Allergy
- Practical issues of oral immunotherapy for egg or milk allergy
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Sukyung Kim, Kangmo Ahn, Jihyun Kim
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Clin Exp Pediatr. 2024;67(3):140-148. Published online June 19, 2023
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· Oral immunotherapy should be supervised by pediatricians with experience administering oral food challenge tests and managing allergic reactions.
· Food allergen intake is gradually increased and maintained for years.
· Patients may experience allergic reactions and psychological problems.
· Adjunctive therapies (biologics, antihistamines, and leukotriene receptor antagonists) may improve efficacy and safety.
· Contraindications include uncontrolled asthma, malignancy, active autoimmune disorders, and beta-blocker usage. |
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- Editorial
- Allergy
- Advancements in food allergen immunotherapy: improving quality of life and reducing risks
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Jihyun Kim
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Clin Exp Pediatr. 2024;67(12):672-674. Published online July 31, 2024
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· Pediatric food allergies considerably impair patient and family quality of life, particularly those with persistent allergies to common food allergens.
· Recent research has focused on developing diverse approaches to food allergen immunotherapy, showing promising outcomes of oral, sublingual, and epicutaneous immuno therapies.
· Critical considerations in immunotherapy candidate selection underscore the need for personalized approaches and reliable biomarkers in future studies to improve treatment outcomes. |
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- Case Report
- Identification of a novel mutation in the CHD7 gene in a patient with CHARGE syndrome
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Yeonkyung Kim, Ho-Seok Lee, Jung-Seok Yu, Kangmo Ahn, Chang-Seok Ki, Jihyun Kim
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Clin Exp Pediatr. 2014;57(1):46-49. Published online January 31, 2014
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CHARGE syndrome has been estimated to occur in 1:10,000 births worldwide and shows various clinical manifestations. It is a genetic disorder characterized by a specific and a recognizable pattern of anomalies. The major clinical features are ocular coloboma, heart malformations, atresia of the choanae, growth retardation, genital hypoplasia, and ear abnormalities. The chromodomain helicase DNA-binding protein 7 (CHD7) gene, located... |
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- Review Article
- Food allergy
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Youngshin Han, Jihyun Kim, Kangmo Ahn
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Clin Exp Pediatr. 2012;55(5):153-158. Published online May 21, 2012
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Food allergy is an important public health problem affecting 5% of infants and children in Korea. Food allergy is defined as an immune response triggered by food proteins. Food allergy is highly associated with atopic dermatitis and is one of the most common triggers of potentially fatal anaphylaxis in the community. Sensitization to food allergens can occur in the gastrointestinal... |
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- Case Report
- A case of Hyper-IgE syndrome with a mutation of the STAT3 gene
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Ji-man Kang, Jungmun Suh, Jihyun Kim, Hee-Jin Kim, Yae-jean Kim, Hun Seok Lee, Young Kee Shin, Kangmo Ahn, Sang-Il Lee
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Clin Exp Pediatr. 2010;53(4):592-597. Published online April 15, 2010
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Hyperimmunoglobulin E syndrome (HIES) is a rare immunodeficiency disease which is characterized by high serum IgE levels, eczema, and recurrent infections. Herein we present the case of a patient with HIES associated with STAT3 gene (stat3) mutation. A 16 year-old girl was admitted to our hospital due to hemoptysis caused by pneumonia with bronchiectasis. She had a history of recurrent... |
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