- Original Article
- Cardiology
- Clinical implications in laboratory parameter values in acute Kawasaki disease for early diagnosis and proper treatment
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Yu-Mi Seo, Hyun-Mi Kang, Sung-Churl Lee, Jae-Won Yu, Hong-Ryang Kil, Jung-Woo Rhim, Ji-Whan Han, Kyung-Yil Lee
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Clin Exp Pediatr. 2018;61(5):160-166. Published online May 28, 2018
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Purpose This study aimed to analyse laboratory values according to fever duration, and evaluate the relationship across these values during the acute phase of Kawasaki disease (KD) to aid in the early diagnosis for early-presenting KD and incomplete KD patients. MethodsClinical and laboratory data of patients with KD (n=615) were evaluated according to duration of fever at presentation, and were compared between... |
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- Case Report
- Giant Coronary and Axillary Aneurysms in an Infant with Kawasaki Disease Associated with Thrombocytopenia
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Sei Young Seo, Jin Hee Oh, Jong-Hyun Kim, Ji-Whan Han, Kyung-Yil Lee, Dae Kyun Koh
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Clin Exp Pediatr. 2005;48(8):901-906. Published online August 15, 2005
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Kawasaki disease (KD) is a leading cause of acquired heart disease in children. Yet the etiology of KD is still unknown and diagnosis depends on the exclusion of other diseases and the clinical manifestations meeting the defined criteria. Young infants frequently show atypical clinical courses and are frequently complicated with coronary aneurysms. Some cases show thrombocytopenia, which is known as... |
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- An Epidemiologic Study of Kawasaki Disease(1987-2000) :
Incidence of Coronary Artery Complication in the Acute Stage
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Kyung-Yil Lee, Min-Young Park, Ji-Whan Han, Hyung-Shin Lee, Jin Choi, Kyung-Tai Whang
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Clin Exp Pediatr. 2002;45(6):783-789. Published online June 15, 2002
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Purpose : We evaluated the epidemiologic characteristics and incidence of coronary artery sequele of children with KD according to treatment.
Methods : We retrospectively analyzed 506 medical records of children with KD, who were admitted at Daejeon St. Mary's Hospital from Jan. 1987 to Dec. 2000.
Results : The mean annual incidence was 36.1±11.1 cases per year. There was a slightly higher... |
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- Case Report
- A Case of Acute Renal Failure Following Intravenous Immunoglobulin Therapy in a Child
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Sung-Wook Park, Kyung-Yil Lee, Kyung-Yil Lee, Kye-Nam Yoon, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Kyung-Tai Whang
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Clin Exp Pediatr. 2000;43(5):720-724. Published online May 15, 2000
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Intravenous immunoglobulin(IVIG) therapy is associated with a number of complications, including rare acute renal failure(ARF). Although the cause of IVIG-associated ARF is unknown, it may be related to the stabilizing agent used in IVIG preparations. ARF following IVIG infusion has not been previously described in children. We report a 4-year-old girl with Kawasaki disease who suffered from ARF following IVIG... |
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- Original Article
- Clinical Study of Recurrent Parotitis in Children
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Sam-Hwa Yim, Kye-Nam Yoon, Kyung-Yil Lee, Sang-Won Cha, Dong-Jun Lee, Ji-Whan Han, Jin-Han Kang, Kyung-Tai Whang
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Clin Exp Pediatr. 2000;43(5):619-624. Published online May 15, 2000
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Purpose : Recurrent parotitis is defined as a recurrent parotid inflammation, generally associated with sialectasis of the parotid gland. It can often be misdiagnosed as recurrent mumps. We studied the clinical and laboratory features of recurrent parotitis.
Methods : Outpatient clinical records of 23 cases were analyzed retrospectively between April 1993 and March 1999. Follow-up after the last outpatient clinic... |
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- Case Report
- A Case of Common Variable Immunodeficiency with Autoimmune Hemolytic Anemia
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Kyung-Yil Lee, Yon-Joo Lee, Sang-Won Cha, Dong Joon Lee, Ji-Whan Han, Kyung-Tae Whang, Joong-Gon Kim
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Clin Exp Pediatr. 2000;43(1):117-122. Published online January 15, 2000
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Common variable immunodeficiency(CVID) is a heterogeneous collection of disorders with hypogammaglobulinemia
with recurrent bacterial infections and high incidence of autoimmune disorders
as its hallmark. We report a 7-year-old girl suffering from CVID with Coombs' test positive
hemolytic anemia. She had been relatively well until 23-months old when she was admitted to
Taejon St. Mary' s Hospital with pneumonia 5 years ago. Afterwards, she had... |
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- A Case of Guillain-Barré Syndrome Coinciding with Bronchial Asthma associated with Mycoplasma Pneumonia
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Kyung-Yil Lee, Dong-Joon Lee, Ji-Whan Han, Sang-Won Ch, John-Sung Lee, Kyung-Tai Whang
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Clin Exp Pediatr. 1999;42(8):1165-1169. Published online August 15, 1999
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Mycoplasma pneumoniae is the most common etiologic agent of pneumonia in school-aged children and young adults. It involves not only the respiratory system but includes extrapulmonary complications such as exanthem, hemolysis, arthritis, hepatic dysfuction, cardiac disease, and central nervous system disease. The pathogenesis of extrapulmonary involvements may be an autoimmune phenomena. Recent studies suggest that bronchial asthma can be initiated... |
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- Original Article
- Clinical Analysis and Comparison of Kawasaki Disease between Patients Younger than One Year of Age and Those over One Year of Age
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Hee-Sun Chung, Kyung-Yil Lee, Ji-Whan Han, Sang-Won Cha, Dong-Joon Lee, Kyung-Tai Whang
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Clin Exp Pediatr. 1999;42(7):936-942. Published online July 15, 1999
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Purpose : To identify the risk factors for coronary sequelae in Kawasaki disease, we analyzed and compared the clinical features and laboratory findings of Kawasaki disease in patients younger than one year of age with those over one year of age.
Methods : A retrospective chart review was conducted of all children with Kawasaki disease who were admitted to the... |
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- Case Report
- A Case of Kawasaki Disease Diagnosed with the Assistance of Ophthalmologic Examination
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Soo-Jung Ha, Kyung-Yil Lee, Sang-Won Cha, Dong-Joon Lee, Ji-Whan Han, Kyung-Tai Whang, Ik-Soo Kim
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Clin Exp Pediatr. 1999;42(7):1014-1018. Published online July 15, 1999
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Kawasaki disease is a systemic vasculitis in which bilateral nonexudative conjunctivitis and anterior uveitis are common early findings in the course of illness. We report an eleven-year-old boy with atypical Kawasaki disease who was diagnosed with the help of an ophthalmologic examination. The patient presented with fever, epigastric pain with vomiting, erythematous rash, and severe bilateral conjunctival injection, a red... |
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- Original Article
- Immunologic Alterations of Peripheral Mononuclear Cells by Intravenous Immunoglobulin in the Acute Stage of Kawasaki disease
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Ji-Whan Han, Kyung-Yil Lee, Kyong-Su Lee
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Clin Exp Pediatr. 1998;41(6):813-824. Published online June 15, 1998
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Purpose : High dose intravenous immunoglobulin(IVIG) therapy is effective in reducing the
incidence of coronary artery aneurysm in Kawasaki disease(KD) patients, however, the precise
mechanisms by which IVIG reverses the immune activation is unknown.
Methods : The sera and peripheral mononuclear cells(PBMCs) were obtained from 10 KD patients
in the acute stage(24 hrs before) and 24 hrs after one dose of IVIG(2g/kg) treatment. We
measured... |
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- Case Report
- Reccurent Unilateral Lung Collapse in an Asthmatic Child
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Yul-Yi Yeon, Kyung-Yil Lee, Dong-Jun Lee, Ji-Whan Han, Sung-Soo Hwang, Kyong-Su Lee
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Clin Exp Pediatr. 1998;41(6):850-854. Published online June 15, 1998
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Abnomalities in the production and transport of airway secretions play an important role in the
pathophysiology of asthma. Segmental atelectasis as a complication of asthma, is relatively common
in children. On the other hand, massive atelectasis such as the collapse of one lung is a very
rare occurence. We report a seven-year-old male asthmatic patient with right lung collapse caused
by mucoid impaction. Fourteen... |
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- Original Article
- Treatment of Intravenous Immune-Globulin Resistant Kawasaki Disease with Corticosteroids
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Dae-Eui Hong, Kyung-Yil Lee, Ji-Whan Han, Sung-Soo Hwang, Kyong-Su Lee
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Clin Exp Pediatr. 1997;40(10):1453-1457. Published online October 15, 1997
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Purpose : To evaluate the efficacy of steroid therapy on prevention of development and progression
of coronary artery aneurysm in intravenous immune globulin(IVIG)-resistant Kawasaki disease, we
treated three children with high dose of intravenous methylprednisolone followed by low dose oral
prednisolone.
Methods : We selected three children with Kawasaki disease who did not repond or who initially
responded but soon developed recrudescent fever after retreatment... |
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- Case Report
- A Case of Acute Viral Myositis
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Jong-Hoon Kwak, Kyung-Yil Lee, Ji-Whan Han, Sung-Soo Hwang, Jae-Kyun Huh, Kyong-Su Lee
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Clin Exp Pediatr. 1996;39(4):572-576. Published online April 15, 1996
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Diffuse myalgia is common in transient systemic viral infections but overt myositis, with weakness and signs of muscle inflammation, rarely accompanies viral infection in chidren. We describe a 8-year-old boy with severe myalgia and tenderness in both lower extremities, whose unusual skeletal muscle uptake on Technetium-methylene diphosphate bone scan helped to diagnosis of myositis. Clinical course, muscle-derived enzyme studies(AST, ALT,... |
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- Original Article
- A Clinical Observation of Kawasaki Meningitis and Viral Meningitis
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Jae-Ho Hyun, Young-Hoon Kim, Ji-Whan Han, Jong-Wan Kim, Kyung-Tai Whang
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Clin Exp Pediatr. 1995;38(6):794-803. Published online June 15, 1995
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Purpose : This study was performed to investigate the clinical characteristics in Kawasaki meningitis and viral meningitis.
Methods : A clinical observation and comparison were carried out on 37 patients of Kawasaki disease with meningitis(group A) and 28 patients of Kawasaki disease without meningitis (group B) who were admitted to Catholic Medical Center from July, 1991 to June, 1993 and 100... |
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