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Il-Young Jo (Jo IY)

1 Article

Original Article

Effect of Granulocyte-macrophage Colony-stimulating Factor in Neonatal Infection

Il-Young Jo, Sang-Hyun Byun

Clin Exp Pediatr. 2000;43(12):1552-1557. Published online December 15, 2000

Purpose : Neutrophils are central to the defences against bacterial infection, and in neonates the number of neutrophils are decreased due to inhibited production and phagocytic function. This induces high mortality rates in infants suffering from neonatal sepsis. Exogenous GM-CSF can increase the number of neutrophils and improve the phagocytic function. To establish the most cost effective dose of exogenous...

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